318 research outputs found
Parity-violating asymmetry in with a pionless effective theory
Nuclear parity violation is studied with polarized neutrons in the
photodisintegration of the deuteron at low energies. A pionless effective field
theory with di-baryon fields is used for the investigation. Hadronic weak
interactions are treated by parity-violating di-baryon-nucleon-nucleon
vertices, which have undetermined coupling contants. A parity-violating
asymmetry in the process is calculated for the incident photon energy up to 30
MeV. If experimental data for the parity-violating asymmetry become available
in the future, we will be able to determine the unknown coupling contants in
the parity-violating vertices.Comment: 4 pages. A contribution to APFB2011, August 22-26, 2011, Seoul, Kore
Finite temperature scaling theory for the collapse of Bose-Einstein condensate
We show how to apply the scaling theory in an inhomogeneous system like
harmonically trapped Bose condensate at finite temperatures. We calculate the
temperature dependence of the critical number of particles by a scaling theory
within the Hartree-Fock approximation and find that there is a dramatic
increase in the critical number of particles as the condensation point is
approached.Comment: Published online [6 pages, 3 figures
IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in jak2v617f-positive myeloproliferative neoplasms
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)The recurrent V617F mutation in JAK2 (JAK2(V617F)) has emerged as the primary contributor to the pathogenesis of myeloproliferative neoplasms (MPN). However, the lack of complete response in most patients treated with the JAK1/2 inhibitor, ruxolitinib, indicates the need for identifying pathways that cooperate with JAK2. Activated JAK2 was found to be associated with the insulin receptor substrate 2 (IRS2) in non-hematological cells. We identified JAK2/IRS2 binding in JAK2(V617F) HEL cells, but not in the JAK2(WT) U937 cell line. In HEL cells, IRS2 silencing decreased STAT5 phosphorylation, reduced cell viability and increased apoptosis; these effects were enhanced when IRS2 silencing was combined with ruxolitinib. In U937 cells, IRS2 silencing neither reduced cell viability nor induced apoptosis. IRS1/2 pharmacological inhibition in primary MPN samples reduced cell viability in JAK2(V617F)-positive but not JAK2(WT) specimens; combination with ruxolitinib had additive effects. IRS2 expression was significantly higher in CD34(+) cells from essential thrombocythemia patients compared to healthy donors, and in JAK2(V617F) MPN patients when compared to JAK2(WT). Our data indicate that IRS2 is a binding partner of JAK2(V617F) in MPN. IRS2 contributes to increased cell viability and reduced apoptosis in JAK2-mutated cells. Combined pharmacological inhibition of IRS2 and JAK2 may have a potential clinical application in MPN.The recurrent V617F mutation in JAK2 (JAK2V617F) has emerged as the primary contributor to the pathogenesis of myeloproliferative neoplasms (MPN). However, the lack of complete response in most patients treated with the JAK1/2 inhibitor, ruxolitinib, indi7669486959sem informaçãoConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)sem informaçã
On Parity-Violating Three-Nucleon Interactions and the Predictive Power of Few-Nucleon EFT at Very Low Energies
We address the typical strengths of hadronic parity-violating three-nucleon
interactions in "pion-less" Effective Field Theory in the nucleon-deuteron
(iso-doublet) system. By analysing the superficial degree of divergence of loop
diagrams, we conclude that no such interactions are needed at leading order.
The only two linearly independent parity-violating three-nucleon structures
with one derivative mix two-S and two-P-half waves with iso-spin transitions
Delta I = 0 or 1. Due to their structure, they cannot absorb any divergence
ostensibly appearing at next-to-leading order. This observation is based on the
approximate realisation of Wigner's combined SU(4) spin-isospin symmetry in the
two-nucleon system, even when effective-range corrections are included.
Parity-violating three-nucleon interactions thus only appear beyond
next-to-leading order. This guarantees renormalisability of the theory to that
order without introducing new, unknown coupling constants and allows the direct
extraction of parity-violating two-nucleon interactions from three-nucleon
experiments.Comment: 20 pages LaTeX2e, including 9 figures as .eps file embedded with
includegraphicx. Minor modifications and stylistic corrections. Version
accepted for publication in Eur. Phys. J.
The First Detection of Cobalt in a Damped Lyman Alpha System
We present the first ever detection of Cobalt in a Damped Lyman Alpha system
(DLA) at z = 1.92. In addition to providing important clues to the star
formation history of these high redshift galaxies, we discuss how studying the
Co abundance in DLAs may also help to constrain models of stellar
nucleosynthesis in a regime not probed by Galactic stars.Comment: 4 pages, to appear in the proceedings of `New Quests in Stellar
Astrophysics: The Link Between Stars and Cosmology', eds. M. Chavez, A.
Bressan, A. Buzzoni, D. Mayy
Revising the Local Bubble Model due to Solar Wind Charge Exchange X-ray Emission
The hot Local Bubble surrounding the solar neighborhood has been primarily
studied through observations of its soft X-ray emission. The measurements were
obtained by attributing all of the observed local soft X-rays to the bubble.
However, mounting evidence shows that the heliosphere also produces diffuse
X-rays. The source is solar wind ions that have received an electron from
another atom. The presence of this alternate explanation for locally produced
diffuse X-rays calls into question the existence and character of the Local
Bubble. This article addresses these questions. It reviews the literature on
solar wind charge exchange (SWCX) X-ray production, finding that SWCX accounts
for roughly half of the observed local 1/4 keV X-rays found at low latitudes.
This article also makes predictions for the heliospheric O VI column density
and intensity, finding them to be smaller than the observational error bars.
Evidence for the continued belief that the Local Bubble contains hot gas
includes the remaining local 1/4 keV intensity, the observed local O VI column
density, and the need to fill the local region with some sort of plasma. If the
true Local Bubble is half as bright as previously thought, then its electron
density and thermal pressure are 1/square-root(2) as great as previously
thought, and its energy requirements and emission measure are 1/2 as great as
previously thought. These adjustments can be accommodated easily, and, in fact,
bring the Local Bubble's pressure more in line with that of the adjacent
material. Suggestions for future work are made.Comment: 9 pages, refereed, accepted for publication in the proceedings of the
"From the Outer Heliosphere to the Local Bubble: Comparisons of New
Observations with Theory" conference and in Space Science Review
Homodyne Bell's inequalities for entangled mesoscopic superpositions
We present a scheme for demonstrating violation of Bell's inequalities using
a spin-1/2 system entangled with a pair of classically distinguishable wave
packets in a harmonic potential. In the optical domain, such wave packets can
be represented by coherent states of a single light mode. The proposed scheme
involves standard spin-1/2 projections and measurements of the position and the
momentum of the harmonic oscillator system, which for a light mode can be
realized by means of homodyne detection. We discuss effects of imperfections,
including non-unit efficiency of the homodyne detector, and point out a close
link between the visibility of interference and violation of Bell's
inequalities in the described scheme.Comment: 6 pages, 3 figures. Extended version, journal reference adde
A study of orientational ordering in a fluid of dipolar Gay-Berne molecules using density-functional theory
Published versio
What Physical Processes Drive the Interstellar Medium in the Local Bubble?
Recent 3D high-resolution simulations of the interstellar medium in a star form-
ing galaxy like the Milky Way show that supernova explosions are the main driver of the
structure and evolution of the gas. Its physical state is largely controlled by turbulence due
to the high Reynolds numbers of the average flows. For a constant supernova rate a dynam-
ical equilibrium is established within 200 Myr of simulation as a consequence of the setup
of a galactic fountain. The resulting interstellar medium reveals a typical density/pressure
pattern, i.e. distribution of so-called gas phases, on scales of 500–700 pc, with interstellar
bubbles being a common phenomenon just like the Local Bubble and the Loop I superbub-
ble, which are assumed to be interacting. However, modeling the Local Bubble is special,
because it is driven by a moving group, passing through its volume, as it is inferred from
the analysis of Hipparcos data. A detailed analysis reveals that between 14 and 19 super-
novae have exploded during the last 15 Myr. The age of the Local Bubble is derived from
comparison with HI and UV absorption line data to be 14.5±0.7
Myr. We further predict the
0.4merging of the two bubbles in about 3 Myr from now, when the interaction shell starts to
fragment. The Local Cloud and its companion HI clouds are the consequence of a dynamical
instability in the interaction shell between the Local and the Loop I bubble
Raditive decay of single charmed baryons
The electromagnetic transitions between () and
() baryons are important decay modes to observe new hadronic
states experimentally. For the estimation of these transitions widths, we
employ a non-relativistic quark potential model description with color coulomb
plus linear confinement potential. Such a description has been employed to
compute the ground state masses and magnetic moments of the single heavy flavor
baryons. The magnetic moments of the baryons are obtained using the spin-flavor
structure of the constituting quark composition of the baryon. Here, we also
define an effective constituent mass of the quarks (ecqm) by taking into
account the binding effects of the quarks within the baryon. The radiative
transition widths are computed in terms of the magnetic moments of the baryon
and the photon energy. Our results are compared with other theoretical models.Comment: 06 Pages, Presented at XVIII DAE-BRNS symposium on High energy
Physics, Banaras Hindu University, Varansi, INDI
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