A study of commercial vehicle brake judder transmission using multi-body dynamic analysis

YesBraking-induced forced vibration, known as brake judder in road vehicles, causes dissatisfaction to drivers and passengers and also damage and possible early failure in components and systems. In this paper, the transmission of judder vibration from the point of generation (the brake friction pair) through the vehicle structure to the driver is investigated for the particular case of a heavy commercial vehicle. The investigation uses a computer simulation multi-body dynamic model based on the automatic dynamic analysis of mechanical systems software to identify any characteristics of the vehicle suspension design that might influence the vibration transmission from the wheel to the driver. The model uses a simplified rigid chassis and cab to lump the chassis parameters, so that the investigation can focus on the front axle/suspension design, which is a beam axle leaf spring arrangement, and the rear axle/suspension assembly, which is a tandem axle bogie design. Results from the modelling indicate that brake judder vibration is transmitted to the chassis of the vehicle through a leaf spring `wind-up¿ mode and a `walking¿ mode associated with the rear tandem axle. Of particular interest is the longitudinal vibration transmitted through the chassis, since this creates a direct vibration transmission path to the cab and driver. The simulation results were compared with the previously published experimental work on the same design of commercial vehicle, and agreement between the predicted and the measured vibration characteristics and frequencies was found. It is concluded that the rear suspension design parameters could affect the transmission of brake judder vibration to the cab and driver and that a tandem rear axle offers some design opportunity to control the transmission of brake judder vibrations from the wheel to the cab and driver. Given that brake judder has so far defied all attempts to eliminate completely from vehicle brake systems, this is potentially an important opportunity

Analysis of radiation-induced bystander effects using high content screening

When cells are exposed to (ionising) radiation there is a rapid phosphorylation of a minor nucleosomal histone protein, H2AX, at the sites where double stranded breaks (DSB) occur. This phosphorylation is one of the earliest events in the repair cascade and extends over several mega base pairs surrounding the break. Nowadays it is generally accepted that the formation of γH2AX functions as a signal enhancer. Using immuno histochemistry we can visualise this phosphorylation as foci in the nucleus, where each foci represents a DSB [1]. For our research we use normal human primary fibroblasts (NHDF’s) to study the so called radiation-induced bystander effects which refer to the responses induced in non-irradiated cells, when neighbouring cells are irradiated. Although the exact pathways of transmission are yet to be determined, studies have shown that gap junction-mediated transport and secretion of soluble extracellular factors play an important role [2]. To exclude variation we first tried synchronisation of the fibroblasts using nocodazole or aphidicolin. Our attempts did not produce the desired synchronisation level. In addition, recent reports doubt the effectiveness of these products in cell synchronisation [3]. To resolve this problem, we used high content screening of cells together with specific cell cycle markers. One of these markers is 5-bromo-2-deoxyuridine (BrdU). BrdU, a synthetic nucleoside, is an analogue of thymidine that can be incorporated in replicating cells and specifically label S-phases [4]. Cells are cultured on membrane inserts, with a pore size of 0,4µm allowing soluble factors to pass but preventing the cells to interchange. These cells are irradiated with different doses and subsequently placed together with NHDF that are grown on cover glasses (see figure 1). Depending on the objectives BrdU is added 20-40 minutes before fixation. We found a differential pattern for γH2AX that we could specifically link to the cell cycle. During the S phase γH2AX is significantly more induced than during other phases of the cell cycle (see figure 2). This is probably due to the increased vulnerability caused by the unwinding of DNA during replication. 1. ¬¬S.H.Macphail, J.P.Banath, T.Y.Yu, E.H.Chu, H.Lambur, P.L.Olive, Int.J.Radiat.Biol. 79 (2003) P. 351-358. 2. H.Yang, N.Asaad, K.D.Held, Oncogene 24 (2005) p. 2096-2103. 3. S.Cooper, G.Iyer, M.Tarquini, P.Bissett, Cell Tissue Res. 324 (2006) p.237-242. 4. R.T.O'Keefe, S.C.Henderson, D.L.Spector, J.Cell Biol. 116 (1992) p.1095-1110

How the Internet of Things Technology Enhances Emergency Response Operations

The Internet of Things (IoT) is a novel paradigmthat connects the pervasive presence around us of a variety of things or objects to the Internet by using wireless/wired technologies to reach desired goals. Since the concept of the IoT was introduced in 2005, we see the deployment of a new generation of networked smart objects with communication, sensory and action capabilities for numerous applications, mainly in global supply chain management, environment monitoring and other non-stress environments. This paper introduces the IoT technology for use in the emergency management community. Considering the information required for supporting three sequential and distinct rhythms in emergency response operations: mobilization rhythm, preliminary situation assessment rhythm, and intervention rhythm, the paper proposes a modified task-technology fit approach that is used to investigate how the IoT technology can be incorporated into the three rhythms and enhance emergency response operations. The findings from our research support our two hypotheses: H1: IoT technology fits the identified information requirements; and H2: IoT technology provides added value to emergency response operations in terms of obtaining efficient cooperation, accurate situational awareness, and complete visibility of resources

Stock assessment of Queensland east coast dusky flathead (Platycephalus fuscus), Australia, with data to December 2020

In Queensland, dusky flathead (Platycephalus fuscus) are found in inshore waters of east coastal regions from south of Cairns to the New South Wales (NSW) border and targeted by commercial, charter and recreational fishers. Dusky flathead are a gonochore (born male or female and does not change sex) and spawn primarily in the summer months. Female dusky flathead grow much larger and live longer than males. For Queensland’s east coast, they generally attain maximum average length of 85 cm (total length) and live for 11 years. Dusky flathead are believed to be a single population on the east coast of Queensland. Eighteen scenarios were run to cover a range of modelling assumptions and sensitivity tests for the stock model. Base case (most plausible) results suggested that the dusky flathead biomass experienced a decline in the period of 1901–2000 to reach 30% unfished spawning biomass (Figure 3). At the beginning of 2021, the stock level was estimated to be 46% unfished biomass with the 95% confidence interval between 31% and 62%. The East coast inshore fishery harvest strategy: 2021–2026 identifies a target reference point (Btarg) of between 50 and 60 % for tier 2 species within the fishery which applies to dusky flathead (Fisheries Queensland (2021b)). This variation in biomass targets for tier 2 species recognises different biological and economic characteristics among target species in the fishery. The equilibrium yield curve produced as part of this assessment suggests that a 50 % target reference point would maintain the stock in a more productive state than a 60 % target, and is therefore likely to be the most reflective of MEY. The harvest consistent with maintaining a spawning biomass of 50% was estimated at 138 t and for rebuilding the stock back to 50% target, the assessment recommends a biological catch of 106 t for 2021. The harvest consistent with maintaining a spawning biomass of 60% was estimated at 112 t. For a 60% target, the assessment recommends a biological catch of 60 t for 2021(Table 1)

Impact of E-business Technology on Operational Competence and Firm Profitability over Time

This study examines the evolution of the impact of e-business technology on operational competence and profitability using a panel dataset of 154 Spanish firms. We find that: (1) E-business technology has a positive effect on operational competence that decreases over time; and (2) the firm\u27s proficiency in exploiting a portfolio of operational capabilities has a positive impact on profitability that becomes more significant over time. The findings provide some insights on how the initial and subsequent IT investments affect operational competence and profitability over time. This study illustrates methodologically how to perform a partial least squares estimation using panel data

Use of Physiologically Based Pharmacokinetic (PBPK) Models in Marine Mammal Toxicology

peer reviewedPhysiologically based pharmacokinetic (PBPK) models are mathematical models that are largely based upon the physiological characteristics of the species and the biochemical properties of the chemical of interest. They quantitatively describe and predict the kinetics of pollutants inside the body and can be of major importance for risk assessment of chemicals in marine mammals. PBPK models which consist of five compartments (liver, blubber, kidney, brain, and the rest of the body) were made for selected polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in order to address the bioaccumulation of these compounds in tissues of harbour porpoises (Phocoena phocoena). Harbour porpoises have relatively long life spans, are common cetaceans in the North Sea, a heavily polluted area, and are known to be very sensitive to pollution. Models developed for all compounds (some PCBs and PBDEs) were evaluated using existing datasets from the literature and from analyses performed by GC-MS, the latter being obtained from stranded porpoises in the Black Sea and the North Sea over a period of 18 years (1990–2008) to assess spatial and temporal trends in bioaccumulation of the respective PCBs and PBDEs. We demonstrate that PBPK models are a feasible computational approach that can be used as a non-destructive tool for predicting the chemical pollution status of the marine mammals

A smart cushion for real-time heart rate monitoring

10.1109/BioCAS.2012.64185122012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications53-5

The Isotope Effect in Superconductors

We review some aspects of the isotope effect (IE) in superconductors. Our focus is on the influence of factors not related to the pairing mechanism. After summarizing the main results obtained for conventional superconductors, we review the effect of magnetic impurities, the proximity effect and non-adiabaticity on the value of the isotope coefficient (IC). We discuss the isotope effect of $T_c$ and of the penetration depth $\delta$. The theory is applied to conventional and high-$T_c$ superconductors. Experimental results obtained for YBa$_2$Cu$_3$O$_{7-\delta}$ related materials (Zn and Pr-substituted as well as oxygen-depleted systems) and for La$_{2-x}$Sr$_x$CuO$_4$ are discussed.Comment: 31 pages, 10 figures. Review article to appear in "Pair Correlation in Many Fermions Systems", Plenum Press 199