1,360 research outputs found
Значение и сущность знаний в экономике Украины
Проанализированы взгляды различных авторов на значение и сущность знаний в экономике Украины. Проведены исследования систем классифицирования современной отрасли экономической науки «экономика знаний». Результатом исследований является уточнение термина, а также введение новых типов классификации знаний.Проаналізовані погляди різних авторів на значення і сутність знань в економіці України. Проведені дослідження систем класифікації сучасної галузі економічної науки «економіка знань». Результатом дослідження є уточнення терміну, а також введення нових типів класифікації знань.The paper analyzes the views of different authors on the
importance and essence of knowledge in the economy of
Ukraine. The system of classification of such branch of the economic science as “knowledge economy” has been investigated.
The result of investigation is the term specification, as wel as the
introduction of new types of knowledge classification
Conserved Quasilocal Quantities and General Covariant Theories in Two Dimensions
General matterless--theories in 1+1 dimensions include dilaton gravity,
Yang--Mills theory as well as non--Einsteinian gravity with dynamical torsion
and higher power gravity, and even models of spherically symmetric d = 4
General Relativity. Their recent identification as special cases of
'Poisson--sigma--models' with simple general solution in an arbitrary gauge,
allows a comprehensive discussion of the relation between the known absolutely
conserved quantities in all those cases and Noether charges, resp. notions of
quasilocal 'energy--momentum'. In contrast to Noether like quantities,
quasilocal energy definitions require some sort of 'asymptotics' to allow an
interpretation as a (gauge--independent) observable. Dilaton gravitation,
although a little different in detail, shares this property with the other
cases. We also present a simple generalization of the absolute conservation law
for the case of interactions with matter of any type.Comment: 21 pages, LaTeX-fil
Thermal Giant Graviton with Non-commutative Dipole Field
Using the type II near-extremal 3D-branes solution we apply the T-duality and
smeared twist to construct the supergravity backgrounds which dual to the 4D
finite temperature non-commutative dipole field theories. We first consider the
zero-temperature system in which, depending on the property of dipole vectors
it may be N=2, N=1 or N=0 theory. We investigate the rotating D3-brane
configurations moving on the spactimes and show that, for the cases of N=2 and
N =1 the rotating D3-brane could be blowed up to the stable spherical
configuration which is called as giant graviton and has a less energy than the
point-like graviton. The giant graviton configuration is stable only if its
angular momentum was less than a critical value of which is an increasing
function of the dipole strength. For the case of non-supersymmetric theory,
however, the spherical configuration has a larger energy than the point-like
graviton. We also find that the dipole field always render the dual giant
graviton to be more stable than the point-like graviton. The relation of dual
giant graviton energy with its angular momentum, which in the AdS/CFT
correspondence being the operator anomalous dimension is obtained. We
furthermore show that the temperature does not change the property of the giant
graviton, while it will render the dual giant graviton to be unstable.Comment: Latex 20 pages, add comments about BPS bound below (3.8
Space-time inhomogeneity, anisotropy and gravitational collapse
We investigate the evolution of non-adiabatic collapse of a shear-free
spherically symmetric stellar configuration with anisotropic stresses
accompanied with radial heat flux. The collapse begins from a curvature
singularity with infinite mass and size on an inhomogeneous space-time
background. The collapse is found to proceed without formation of an even
horizon to singularity when the collapsing configuration radiates all its mass
energy. The impact of inhomogeneity on various parameters of the collapsing
stellar configuration is examined in some specific space-time backgrounds.Comment: To appear in Gen. Relativ. Gra
A New Approach to Searching for Dark Matter Signals in Fermi-LAT Gamma Rays
Several cosmic ray experiments have measured excesses in electrons and
positrons, relative to standard backgrounds, for energies from ~ 10 GeV - 1
TeV. These excesses could be due to new astrophysical sources, but an
explanation in which the electrons and positrons are dark matter annihilation
or decay products is also consistent. Fortunately, the Fermi-LAT diffuse gamma
ray measurements can further test these models, since the electrons and
positrons produce gamma rays in their interactions in the interstellar medium.
Although the dark matter gamma ray signal consistent with the local electron
and positron measurements should be quite large, as we review, there are
substantial uncertainties in the modeling of diffuse backgrounds and,
additionally, experimental uncertainties that make it difficult to claim a dark
matter discovery. In this paper, we introduce an alternative method for
understanding the diffuse gamma ray spectrum in which we take the intensity
ratio in each energy bin of two different regions of the sky, thereby canceling
common systematic uncertainties. For many spectra, this ratio fits well to a
power law with a single break in energy. The two measured exponent indices are
a robust discriminant between candidate models, and we demonstrate that dark
matter annihilation scenarios can predict index values that require "extreme"
parameters for background-only explanations.Comment: v1: 11 pages, 7 figures, 1 table, revtex4; v2: 13 pages, 8 figures, 1
table, revtex4, Figure 4 added, minor additions made to text, references
added, conclusions unchanged, published versio
Revival of the spin-Peierls transition in Cu_xZn_(1-x)GeO_3 under pressure
Pressure and temperature dependent susceptibility and Raman scattering
experiments on single crystalline Cu_xZn_(1-x)GeO_3 have shown an unusually
strong increase of the spin-Peierls phase transition temperature upon applying
hydrostatic pressure. The large positive pressure coefficient (7.5 K/GPa) -
almost twice as large as for the pure compound (4.5 K/GPa) - is interpreted as
arising due to an increasing magnetic frustration which decreases the spin-spin
correlation length, and thereby weakens the influence of the non-magnetic
Zn-substitution.Comment: LaTeX, 15 pages, 5 eps figures, Phys. Rev. B, to appea
Indirect Dark Matter Detection from Dwarf Satellites: Joint Expectations from Astrophysics and Supersymmetry
We present a general methodology for determining the gamma-ray flux from
annihilation of dark matter particles in Milky Way satellite galaxies, focusing
on two promising satellites as examples: Segue 1 and Draco. We use the
SuperBayeS code to explore the best-fitting regions of the Constrained Minimal
Supersymmetric Standard Model (CMSSM) parameter space, and an independent MCMC
analysis of the dark matter halo properties of the satellites using published
radial velocities. We present a formalism for determining the boost from halo
substructure in these galaxies and show that its value depends strongly on the
extrapolation of the concentration-mass (c(M)) relation for CDM subhalos down
to the minimum possible mass. We show that the preferred region for this
minimum halo mass within the CMSSM with neutralino dark matter is ~10^-9-10^-6
solar masses. For the boost model where the observed power-law c(M) relation is
extrapolated down to the minimum halo mass we find average boosts of about 20,
while the Bullock et al (2001) c(M) model results in boosts of order unity. We
estimate that for the power-law c(M) boost model and photon energies greater
than a GeV, the Fermi space-telescope has about 20% chance of detecting a dark
matter annihilation signal from Draco with signal-to-noise greater than 3 after
about 5 years of observation
Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy
BACKGROUND: Myocardial fibrosis is a hallmark of hypertrophic cardiomyopathy and a proposed substrate for arrhythmias and heart failure. In animal models, profibrotic genetic pathways are activated early, before hypertrophic remodeling. Data showing early profibrotic responses to sarcomere-gene mutations in patients with hypertrophic cardiomyopathy are lacking.
METHODS: We used echocardiography, cardiac magnetic resonance imaging (MRI), and serum biomarkers of collagen metabolism, hemodynamic stress, and myocardial injury to evaluate subjects with hypertrophic cardiomyopathy and a confirmed genotype.
RESULTS: The study involved 38 subjects with pathogenic sarcomere mutations and overt hypertrophic cardiomyopathy, 39 subjects with mutations but no left ventricular hypertrophy, and 30 controls who did not have mutations. Levels of serum C-terminal propeptide of type I procollagen (PICP) were significantly higher in mutation carriers without left ventricular hypertrophy and in subjects with overt hypertrophic cardiomyopathy than in controls (31% and 69% higher, respectively; P<0.001). The ratio of PICP to C-terminal telopeptide of type I collagen was increased only in subjects with overt hypertrophic cardiomyopathy, suggesting that collagen synthesis exceeds degradation. Cardiac MRI studies showed late gadolinium enhancement, indicating myocardial fibrosis, in 71% of subjects with overt hypertrophic cardiomyopathy but in none of the mutation carriers without left ventricular hypertrophy.
CONCLUSIONS: Elevated levels of serum PICP indicated increased myocardial collagen synthesis in sarcomere-mutation carriers without overt disease. This profibrotic state preceded the development of left ventricular hypertrophy or fibrosis visible on MRI. (Funded by the National Institutes of Health and others.
De novo erythroleukemia chromosome features include multiple rearrangements, with special involvement of chromosomes 11 and 19
Erythroid leukemia (ERL or AML-M6) is an uncommon subtype of acute myeloid leukemia, the clinical, morphological, and genetic behavior of which needs further characterization. We analyzed a homogeneous group of 23 de novo AML-M6 patients whose bone marrow cells showed complex karyotypes. We also analyzed eight leukemia cell lines with erythroid phenotype, performing detailed molecular cytogenetic analyses, including spectral karyotyping (SKY) in all samples. The main features are: (1) A majority of patients (56%) had hypodiploidy. Loss of genetic material was the most common genetic change, especially monosomies of chromosome 7 or 18, and deletions of chromosome arm 5q. Taken together, 87% of the cases displayed aberrations involving chromosome 5 or 8. (2) We describe a novel, cryptic, and recurrent translocation, t(11;19)(p11.2;q13.1). Another translocation, t(12;21)(p11.2;q11.2), was found to be recurrent in a patient with ERL and in the K562 cell line. (3) MLL gene rearrangements were detected in 20% of cases (three translocations and three amplifications) and, overall, we defined 52 rearrangements (excluding deletions) with a mean of 2.3 translocations per patient. (4) Of the structural aberrations, 21% involved chromosomes 11 and 19. Most of the rearrangements were unbalanced; only 13 reciprocal translocations were observed. The general picture of chromosomal aberrations in cell lines did not reflect what occurred in patient samples. However, both primary samples and cell lines shared three common breakpoints at 19q13.1, 20q11.2, and 21q11.2. This is the first molecular cytogenetic description of the karyotype abnormalities present in patients with ERL. It should assist in the identification of genes involved in erythroleukemogenesis
Horizons, Constraints, and Black Hole Entropy
Black hole entropy appears to be ``universal''--many independent
calculations, involving models with very different microscopic degrees of
freedom, all yield the same density of states. I discuss the proposal that this
universality comes from the behavior of the underlying symmetries of the
classical theory. To impose the condition that a black hole be present, we must
partially break the classical symmetries of general relativity, and the
resulting Goldstone boson-like degrees of freedom may account for the
Bekenstein-Hawking entropy. In particular, I demonstrate that the imposition of
a ``stretched horizon'' constraint modifies the algebra of symmetries at the
horizon, allowing the use of standard conformal field theory techniques to
determine the asymptotic density of states. The results reproduce the
Bekenstein-Hawking entropy without any need for detailed assumptions about the
microscopic theory.Comment: 16 pages, talk given at the "Peyresq Physics 10 Meeting on Micro and
Macro structures of spacetime
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