1,334 research outputs found
Proton Irradiation of Radiation-Sensitive Mutants of Coprinus Cinereus
This research was sponsored by the National Science Foundation Grant NSF PHY-931478
Preliminary Analysis of Proton Radiation Damage Response in Defective Gamma-Radiation-Sensitive Cells
This research was sponsored by the National Science Foundation Grant NSF PHY-931478
The Effect of Proton Radiation Damage to the RNA Enzyme RNASE-P
This research was sponsored by the National Science Foundation Grant NSF PHY-931478
FISH mapping and molecular organization of the major repetitive sequences of tomato
This paper presents a bird's-eye view of the major repeats and chromatin types of tomato. Using fluorescence in-situ hybridization (FISH) with Cot-1, Cot-10 and Cot-100 DNA as probes we mapped repetitive sequences of different complexity on pachytene complements. Cot-100 was found to cover all heterochromatin regions, and could be used to identify repeat-rich clones in BAC filter hybridization. Next we established the chromosomal locations of the tandem and dispersed repeats with respect to euchromatin, nucleolar organizer regions (NORs), heterochromatin, and centromeres. The tomato genomic repeats TGRII and TGRIII appeared to be major components of the pericentromeres, whereas the newly discovered TGRIV repeat was found mainly in the structural centromeres. The highly methylated NOR of chromosome 2 is rich in [GACA](4), a microsatellite that also forms part of the pericentromeres, together with [GA](8), [GATA](4) and Ty1-copia. Based on the morphology of pachytene chromosomes and the distribution of repeats studied so far, we now propose six different chromatin classes for tomato: (1) euchromatin, (2) chromomeres, (3) distal heterochromatin and interstitial heterochromatic knobs, (4) pericentromere heterochromatin, (5) functional centromere heterochromatin and (6) nucleolar organizer regio
Transition Spectra for a BCS Superconductor with Multiple Gaps: Model Calculations for MgB_2
We analyze the qualitative features in the transition spectra of a model
superconductor with multiple energy gaps, using a simple extension of the
Mattis-Bardeen expression for probes with case I and case II coherence factors.
At temperature T = 0, the far infrared absorption edge is, as expected,
determined by the smallest gap. However, the large thermal background may mask
this edge at finite temperatures and instead the secondary absorption edges
found at Delta_i+Delta_j may become most prominent. At finite T, if certain
interband matrix elements are large, there may also be absorption peaks at the
gap difference frequencies | Delta_i-Delta_j | . We discuss the effect of
sample quality on the measured spectra and the possible relation of these
predictions to the recent infrared absorption measurement on MgB_2
Three-dimensional flux states as a model for the pseudogap phase of transition metal oxides
We propose that the pseudogap state observed in the transition metal oxides
can be explained by a three-dimensional flux state, which exhibits
spontaneously generated currents in its ground state due to electron-electron
correlations. We compare the energy of the flux state to other classes of mean
field states, and find that it is stabilized over a wide range of and
. The signature of the state will be peaks in the neutron diffraction
spectra, the location and intensity of which are presented. The dependence of
the pseudogap in the optical conductivity is calculated based on the parameters
in the model.Comment: submitted to Phys. Rev. B on January 8, 200
String Loop Corrections to Kahler Potentials in Orientifolds
We determine one-loop string corrections to Kahler potentials in type IIB
orientifold compactifications with either N=1 or N=2 supersymmetry, including
D-brane moduli, by evaluating string scattering amplitudes.Comment: 80 pages, 4 figure
Short-Term Radio-X-ray Correlations of Cygnus X-1
We analyze simultaneous radio-X-ray data of Cygnus X-1 from the Ryle
telescope (RT) and RXTE over more than 4 a. We show that apparent correlations
on short time scales in the lightcurves of Cyg X-1 are probably the
coincidental outcome of white noise statistics.Comment: 1 page, 1 figure. Proceedings of the IAU Colloquium 194 "Compact
Binaries in the Galaxy and Beyond", to be published in: Revista Mexicana de
Astronomia y Astrofisica, Conference Serie
Atenolol versus losartan in children and young adults with Marfan's syndrome
BACKGROUND : Aortic-root dissection is the leading cause of death in Marfan's syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers.
METHODS : We conducted a randomized trial comparing losartan with atenolol in children and young adults with Marfan's syndrome. The primary outcome was the rate of aortic-root enlargement, expressed as the change in the maximum aortic-root-diameter z score indexed to body-surface area (hereafter, aortic-root z score) over a 3-year period. Secondary outcomes included the rate of change in the absolute diameter of the aortic root; the rate of change in aortic regurgitation; the time to aortic dissection, aortic-root surgery, or death; somatic growth; and the incidence of adverse events.
RESULTS : From January 2007 through February 2011, a total of 21 clinical centers enrolled 608 participants, 6 months to 25 years of age (mean [+/- SD] age, 11.5 +/- 6.5 years in the atenolol group and 11.0 +/- 6.2 years in the losartan group), who had an aorticroot z score greater than 3.0. The baseline-adjusted rate of change (+/- SE) in the aortic-root z score did not differ significantly between the atenolol group and the losartan group (-0.139 +/- 0.013 and -0.107 +/- 0.013 standard-deviation units per year, respectively; P = 0.08). Both slopes were significantly less than zero, indicating a decrease in the degree of aortic-root dilatation relative to body-surface area with either treatment. The 3-year rates of aortic-root surgery, aortic dissection, death, and a composite of these events did not differ significantly between the two treatment groups.
CONCLUSIONS : Among children and young adults with Marfan's syndrome who were randomly assigned to losartan or atenolol, we found no significant difference in the rate of aorticroot dilatation between the two treatment groups over a 3-year period
Black Holes from Cosmic Rays: Probes of Extra Dimensions and New Limits on TeV-Scale Gravity
If extra spacetime dimensions and low-scale gravity exist, black holes will
be produced in observable collisions of elementary particles. For the next
several years, ultra-high energy cosmic rays provide the most promising window
on this phenomenon. In particular, cosmic neutrinos can produce black holes
deep in the Earth's atmosphere, leading to quasi-horizontal giant air showers.
We determine the sensitivity of cosmic ray detectors to black hole production
and compare the results to other probes of extra dimensions. With n \ge 4 extra
dimensions, current bounds on deeply penetrating showers from AGASA already
provide the most stringent bound on low-scale gravity, requiring a fundamental
Planck scale M_D > 1.3 - 1.8 TeV. The Auger Observatory will probe M_D as large
as 4 TeV and may observe on the order of a hundred black holes in 5 years. We
also consider the implications of angular momentum and possible exponentially
suppressed parton cross sections; including these effects, large black hole
rates are still possible. Finally, we demonstrate that even if only a few black
hole events are observed, a standard model interpretation may be excluded by
comparison with Earth-skimming neutrino rates.Comment: 30 pages, 18 figures; v2: discussion of gravitational infall, AGASA
and Fly's Eye comparison added; v3: Earth-skimming results modified and
strengthened, published versio
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