19 research outputs found
Associations between serum 25-hydroxyvitamin D and sleep, as estimated by actigraphy and the Pittsburgh Sleep Quality Index (PSQI)
An association between seasonal fluctuation ‘cycling’ of 25(OH)D and increased bone resorption but not BMD or BMC in UK South Asian and Caucasian women living at 51on
Daily variation in the content of indoleamines, catecholamines and related compounds in the pineal gland of Syrian hamsters kept under long and short photoperiods
Nocturnal urinary 6-sulphatoxymelatonin excretion is decreased in primary breast cancer patients compared to age-matched controls and shows negative correlation with tumor-size
Do you see what I see? School perspectives of deaf children, hearing children and their parents☆
Environmental Impacts on Congenital Anomalies - Information for the Non-Expert Professional
Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility.
The rhesus macaque (Macaca mulatta) is the most widely studied nonhuman primate (NHP) in biomedical research. We present an updated reference genome assembly (Mmul_10, contig N50 = 46 Mbp) that increases the sequence contiguity 120-fold and annotate it using 6.5 million full-length transcripts, thus improving our understanding of gene content, isoform diversity, and repeat organization. With the improved assembly of segmental duplications, we discovered new lineage-specific genes and expanded gene families that are potentially informative in studies of evolution and disease susceptibility. Whole-genome sequencing (WGS) data from 853 rhesus macaques identified 85.7 million single-nucleotide variants (SNVs) and 10.5 million indel variants, including potentially damaging variants in genes associated with human autism and developmental delay, providing a framework for developing noninvasive NHP models of human disease