90 research outputs found
Hydroacoustics for the discovery and quantification of Nassau grouper (Epinephelus striatus) spawning aggregations
Oceanographic patterns associated with Nassau Grouper aggregation spawn timing: shifts in surface currents on the nights of peak spawning
Tracking potential larval dispersal patterns from Nassau grouper aggregation sites: evidence for local retention and the “importance of place”
Asymptotics of block Toeplitz determinants and the classical dimer model
We compute the asymptotics of a block Toeplitz determinant which arises in
the classical dimer model for the triangular lattice when considering the
monomer-monomer correlation function. The model depends on a parameter
interpolating between the square lattice () and the triangular lattice
(), and we obtain the asymptotics for . For we apply the
Szeg\"o Limit Theorem for block Toeplitz determinants. The main difficulty is
to evaluate the constant term in the asymptotics, which is generally given only
in a rather abstract form
Critical behavior of weakly-disordered anisotropic systems in two dimensions
The critical behavior of two-dimensional (2D) anisotropic systems with weak
quenched disorder described by the so-called generalized Ashkin-Teller model
(GATM) is studied. In the critical region this model is shown to be described
by a multifermion field theory similar to the Gross-Neveu model with a few
independent quartic coupling constants. Renormalization group calculations are
used to obtain the temperature dependence near the critical point of some
thermodynamic quantities and the large distance behavior of the two-spin
correlation function. The equation of state at criticality is also obtained in
this framework. We find that random models described by the GATM belong to the
same universality class as that of the two-dimensional Ising model. The
critical exponent of the correlation length for the 3- and 4-state
random-bond Potts models is also calculated in a 3-loop approximation. We show
that this exponent is given by an apparently convergent series in
(with the central charge of the Potts model) and
that the numerical values of are very close to that of the 2D Ising
model. This work therefore supports the conjecture (valid only approximately
for the 3- and 4-state Potts models) of a superuniversality for the 2D
disordered models with discrete symmetries.Comment: REVTeX, 24 pages, to appear in Phys.Rev.
Crystallography of surface nucleation and epitaxial growth of lithium triniobate on congruent lithium niobate
An investigation into the structure and bioavailability of α-tocopherol dispersions in Gelucire 44/14
In this investigation we describe the preparation, physical characterisation and in vivo behaviour of solid dispersions of a liquid nutraceutical, α-tocopherol, in Gelucire 44/14 with a view to establishing whether dispersion in this matrix may provide a means of formulating a liquid drug in a solid dosage form while also improving the oral bioavailability. Using Vitamin E Preparation USP as the source of α-tocopherol, dispersions were prepared using a melt-fusion method with active loadings up to 50% (w/w) and characterised using differential scanning calorimetry and optical microscopy. Capsules containing 300 IU α-tocopherol were manufactured and the absorption profiles compared to a commercial soft gelatin capsule preparation in healthy human volunteers. Confocal laser scanning microscopy (CLSM) studies were performed in order to elucidate the mechanism by which drug release may be occurring. Differential scanning calorimetry studies indicated that the presence of the active had a negligible effect on the melting profile of the carrier, indicating limited miscibility between the two components, a conclusion supported by the microscopy studies. Similarly, the dispersions were shown to exhibit a glass transition corresponding to the incorporated drug, indicating molecular cooperativity and hence phase separation from the lipid base. Despite the phase separation, it was noted that capsules stored for 18 months under ambient conditions showed no evidence of leakage. Bioavailability studies in six healthy male volunteers indicated that the Gelucire 44/14 formulation showed an approximately two-fold increase in total α-tocopherol absorption compared to the commercial preparation. Confocal laser scanning microscopy studies indicated that, on contact with water, the dispersions formed two interfacial layers, from which the Gelucire 44/14 disperses in the liquid medium as small particles. Furthermore, evidence was obtained for the dispersed material becoming incorporated into the hydrated lipid. In conclusion, the dispersion of the liquid drug in Gelucire 44/14 appears to allow the dual advantages of the preparation of a solid formulation and improved bioavailability of this material
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