Positron-annihilation study of compensation defects in InP

Positron-annihilation lifetime and positron-annihilation Doppler-broadening (PADB) spectroscopies have been employed to investigate the formation of vacancy-type compensation defects in n-type undoped liquid encapsulated Czochrolski grown InP, which undergoes conduction-type conversions under high temperature annealing. N-type InP becomes p-type semiconducting by short time annealing at 700°C, and then turns into n-type again after further annealing but with a much higher resistivity. Long time annealing at 950°C makes the material semi-insulating. Positron lifetime measurements show that the positron average lifetime τ av increases from 245 ps to a higher value of 247 ps for the first n-type to p-type conversion and decreases to 240 ps for the ensuing p-type to n-type conversion. The value of τ av increases slightly to 242 ps upon further annealing and attains a value of 250 ps under 90 h annealing at 950°C. These results together with those of PADB measurements are explained by the model proposed in our previous study. The correlation between the characteristics of positron annihilation and the conversions of conduction type indicates that the formation of vacancy-type defects and the progressive variation of their concentrations during annealing are related to the electrical properties of the bulk InP material. © 2002 American Institute of Physics.published_or_final_versio

Shape complexity and fractality of fracture surfaces of swelled isotactic polypropylene with supercritical carbon dioxide

We have investigated the fractal characteristics and shape complexity of the fracture surfaces of swelled isotactic polypropylene Y1600 in supercritical carbon dioxide fluid through the consideration of the statistics of the islands in binary SEM images. The distributions of area $A$, perimeter $L$, and shape complexity $C$ follow power laws $p(A)\sim A^{-(\mu_A+1)}$, $p(L)\sim L^{-(\mu_L+1)}$, and $p(C)\sim C^{-(\nu+1)}$, with the scaling ranges spanning over two decades. The perimeter and shape complexity scale respectively as $L\sim A^{D/2}$ and $C\sim A^q$ in two scaling regions delimited by $A\approx 10^3$. The fractal dimension and shape complexity increase when the temperature decreases. In addition, the relationships among different power-law scaling exponents $\mu_A$, $\mu_B$, $\nu$, $D$, and $q$ have been derived analytically, assuming that $A$, $L$, and $C$ follow power-law distributions.Comment: RevTex, 6 pages including 7 eps figure

Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer.

BACKGROUND:Although canonical Wnt signaling is known to promote tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), a cancer driven principally by mutant K-Ras, the detailed molecular mechanisms by which the Wnt effector β-catenin regulates such tumorigenesis are largely unknown. We have previously demonstrated that β-catenin's differential usage of the Kat3 transcriptional coactivator cyclic AMP-response element binding protein-binding protein (CBP) over its highly homologous coactivator p300 increases self-renewal and suppresses differentiation in other types of cancer. AIM/METHODS:To investigate Wnt-mediated carcinogenesis in PDAC, we have used the specific small molecule CBP/β-catenin antagonist, ICG-001, which our lab identified and has extensively characterized, to examine its effects in human pancreatic cancer cells and in both an orthotopic mouse model and a human patient-derived xenograft (PDX) model of PDAC. RESULTS/CONCLUSION:We report for the first time that K-Ras activation increases the CBP/β-catenin interaction in pancreatic cancer; and that ICG-001 specific antagonism of the CBP/β-catenin interaction sensitizes pancreatic cancer cells and tumors to gemcitabine treatment. These effects were associated with increases in the expression of let-7a microRNA; suppression of K-Ras and survivin; and the elimination of drug-resistant cancer stem/tumor-initiating cells

Scale-invariance of human EEG signals in sleep

We investigate the dynamical properties of electroencephalogram (EEG) signals of human in sleep. By using a modified random walk method, We demonstrate that the scale-invariance is embedded in EEG signals after a detrending procedure. Further more, we study the dynamical evolution of probability density function (PDF) of the detrended EEG signals by nonextensive statistical modeling. It displays scale-independent property, which is markedly different from the turbulent-like scale-dependent PDF evolution.Comment: 4 pages and 6 figure

Einstein Probe - a small mission to monitor and explore the dynamic X-ray Universe

Einstein Probe is a small mission dedicated to time-domain high-energy astrophysics. Its primary goals are to discover high-energy transients and to monitor variable objects in the $0.5-4~$keV X-rays, at higher sensitivity by one order of magnitude than those of the ones currently in orbit. Its wide-field imaging capability, featuring a large instantaneous field-of-view ($60^\circ \times60^\circ$, $\sim1.1$sr), is achieved by using established technology of micro-pore (MPO) lobster-eye optics, thereby offering unprecedentedly high sensitivity and large Grasp. To complement this powerful monitoring ability, it also carries a narrow-field, sensitive follow-up X-ray telescope based on the same MPO technology to perform follow-up observations of newly-discovered transients. Public transient alerts will be downlinked rapidly, so as to trigger multi-wavelength follow-up observations from the world-wide community. Over three of its 97-minute orbits almost the entire night sky will be sampled, with cadences ranging from 5 to 25 times per day. The scientific objectives of the mission are: to discover otherwise quiescent black holes over all astrophysical mass scales by detecting their rare X-ray transient flares, particularly tidal disruption of stars by massive black holes at galactic centers; to detect and precisely locate the electromagnetic sources of gravitational-wave transients; to carry out systematic surveys of X-ray transients and characterize the variability of X-ray sources. Einstein Probe has been selected as a candidate mission of priority (no further selection needed) in the Space Science Programme of the Chinese Academy of Sciences, aiming for launch around 2020.Comment: accepted to publish in PoS, Proceedings of "Swift: 10 Years of Discovery" (Proceedings of Science; ed. by P. Caraveo, P. D'Avanzo, N. Gehrels and G. Tagliaferri). Minor changes in text, references update

The Online Data Quality Monitoring System at BESIII

The online Data Quality Monitoring (DQM) plays an important role in the data taking process of HEP experiments. BESIII DQM samples data from online data flow, reconstructs them with offline reconstruction software, and automatically analyzes the reconstructed data with user-defined algorithms. The DQM software is a scalable distributed system. The monitored results are gathered and displayed in various formats, which provides the shifter with current run information that can be used to find problems early. This paper gives an overview of DQM system at BESIII.Comment: Already submit to Chinese Physics

Non-uniform Black Strings with Schwarzschild-(Anti-)de Sitter Foliation

We present some exact non-uniform black string solutions of 5-dimensional pure Einstein gravity as well as Einstein-Maxwell-dilaton theory at arbitrary dilaton coupling. The solutions share the common property that their 4-dimensional slices are Schwarzchild-(anti-)de Sitter spacetimes. The pure gravity solution is also generalized to spacetimes of dimensions higher than 5 to get non-uniform black branes.Comment: LaTeX 14 pages, 3 eps figures. V2: version appeared in CQ

Quantum Entanglement and Teleportation in Higher Dimensional Black Hole Spacetimes

We study the properties of quantum entanglement and teleportation in the background of stationary and rotating curved space-times with extra dimensions. We show that a maximally entangled Bell state in an inertial frame becomes less entangled in curved space due to the well-known Hawking-Unruh effect. The degree of entanglement is found to be degraded with increasing the extra dimensions. For a finite black hole surface gravity, the observer may choose higher frequency mode to keep high level entanglement. The fidelity of quantum teleporation is also reduced because of the Hawking-Unruh effect. We discuss the fidelity as a function of extra dimensions, mode frequency, black hole mass and black hole angular momentum parameter for both bosonic and fermionic resources.Comment: 15 pages, 10 figures,contents expande

Full-field implementation of a perfect eavesdropper on a quantum cryptography system

Quantum key distribution (QKD) allows two remote parties to grow a shared secret key. Its security is founded on the principles of quantum mechanics, but in reality it significantly relies on the physical implementation. Technological imperfections of QKD systems have been previously explored, but no attack on an established QKD connection has been realized so far. Here we show the first full-field implementation of a complete attack on a running QKD connection. An installed eavesdropper obtains the entire 'secret' key, while none of the parameters monitored by the legitimate parties indicate a security breach. This confirms that non-idealities in physical implementations of QKD can be fully practically exploitable, and must be given increased scrutiny if quantum cryptography is to become highly secure.Comment: Revised after editorial and peer-review feedback. This version is published in Nat. Commun. 8 pages, 6 figures, 1 tabl