Minimally Allowed Neutrinoless Double Beta Decay Rates From Approximate Flavor Symmetries

Neutrinoless double beta decay ($\beta\beta0\nu$) is among the only realistic probes of Majorana neutrinos. In the standard scenario, dominated by light neutrino exchange, the process amplitude is proportional to $m_{ee}$, the $e-e$ element of the Majorana mass matrix. Naively, current data allows for vanishing $m_{ee}$, but this should be protected by an appropriate flavor symmetry. All such symmetries lead to mass matrices inconsistent with oscillation phenomenology. I perform a spurion analysis to break all possible Abelian symmetries that guarantee vanishing $\beta\beta0\nu$ rates and search for minimally allowed values. I survey 230 broken structures to yield $m_{ee}$ values and current phenomenological constraints under a variety of scenarios. This analysis also extracts predictions for both neutrino oscillation parameters and kinematic quantities. Assuming reasonable tuning levels, I find that $m_{ee}>4\times 10^{-6}$ eV at 99% confidence. Bounds below this value might indicate the Dirac neutrino nature or the existence of new light (eV-MeV scale) degrees of freedom that can potentially be probed elsewhere.Comment: 19 Pages, 4 .eps Figures, 3 Table

A new approach to the inverse problem for current mapping in thin-film superconductors

A novel mathematical approach has been developed to complete the inversion of the Biot-Savart law in one- and two-dimensional cases from measurements of the perpendicular component of the magnetic field using the well-developed Magneto-Optical Imaging technique. Our approach, especially in the 2D case, is provided in great detail to allow a straightforward implementation as opposed to those found in the literature. Our new approach also refines our previous results for the 1D case [Johansen et al., Phys. Rev. B 54, 16264 (1996)], and streamlines the method developed by Jooss et al. [Physica C 299, 215 (1998)] deemed as the most accurate if compared to that of Roth et al. [J. Appl. Phys. 65, 361 (1989)]. We also verify and streamline the iterative technique, which was developed following Laviano et al. [Supercond. Sci. Technol. 16, 71 (2002)] to account for in-plane magnetic fields caused by the bending of the applied magnetic field due to the demagnetising effect. After testing on magneto-optical images of a high quality YBa2Cu3O7 superconducting thin film, we show that the procedure employed is effective

A 40th deg and order gravitational field model for Mars

Understanding the origin and evolution of major photographic features on Mars, such as the hemispheric dichotomy and Tharsis rise, will require improved resolution of that planet's gravitational and topographic fields. The highest resolution gravity model for Mars published to date was derived from Doppler tracking data from the Mariner 9 and Viking 1 and 2 spacecraft, and is of 18th degree and order. That field has a maximum spatial resolution of approx. 600 km, which is comparable to that of the best topographic model. The resolution of previous gravity models was limited not by data density, but rather by the computational resources available at the time. Because this restriction is no longer a limitation, the Viking and Mariner data sets were reanalyzed and a gravitational field was derived complete to the 40th degree and order with a corresponding maximum spatial resolution of 300 km where the data permit

The boundary states and correlation functions of the tricritical Ising model from the Coulomb-gas formalism

We consider the minimal conformal model describing the tricritical Ising model on the disk and on the upper half plane. Using the coulomb-gas formalism we determine its consistents boundary states as well as its 1-point and 2-point correlation functions.Comment: 20 pages, no figure. Version 2:A paragraph for the calculation of the 2-point correlators was added. Some typos and garammatical errors were corrected.Version 3: Equations 24 are modified. Version 4 : new introduction and minor correction

The Boundary Conformal Field Theories of the 2D Ising critical points

We present a new method to identify the Boundary Conformal Field Theories (BCFTs) describing the critical points of the Ising model on the strip. It consists in measuring the low-lying excitation energies spectra of its quantum spin chain for different boundary conditions and then to compare them with those of the different boundary conformal field theories of the $(A_2,A_3)$ minimal model.Comment: 7 pages, no figures. Talk given at the XXth International Conference on Integrable Systems and Quantum Symmetries (ISQS-20). Prague, June 201

The effects of buoyancy on the critical heat flux in forced convection

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76972/1/AIAA-1993-575-151.pd

SWI/SNF regulates a transcriptional programme that induces senescence to prevent liver cancer

Oncogene-induced senescence (OIS) is a potent tumour suppressor mechanism. To identify senescence regulators relevant to cancer, we screened an shRNA library targeting genes deleted in hepatocellular carcinoma (HCC). Here, we describe how knockdown of the SWI/SNF component ARID1B prevents OIS and cooperates with RAS to induce liver tumours. ARID1B controls p16INK4a and p21CIP1a transcription but also regulates DNA damage, oxidative stress and p53 induction, suggesting that SWI/SNF uses additional mechanisms to regulate senescence. To systematically identify SWI/SNF targets regulating senescence, we carried out a focused shRNA screen. We discovered several new senescence regulators including ENTPD7, an enzyme that hydrolyses nucleotides. ENTPD7 affects oxidative stress, DNA damage and senescence. Importantly, expression of ENTPD7 or inhibition of nucleotide synthesis in ARID1B-depleted cells results in re-establishment of senescence. Our results identify novel mechanisms by which epigenetic regulators can affect tumor progression and suggest that pro-senescence therapies could be employed against SWI/SNF-mutated cancers

Promoter Recognition by a Complex of Spx and the C-Terminal Domain of the RNA Polymerase α Subunit

Spx, an ArsC (arsenate reductase) family member, is a global transcriptional regulator of the microbial stress response and is highly conserved amongst Gram-positive bacteria. Bacillus subtilis Spx protein exerts positive and negative control of transcription through its interaction with the C-terminal domain of the RNA polymerase (RNAP) alpha subunit (alphaCTD). Spx activates trxA (thioredoxin) and trxB (thioredoxin reductase) in response to thiol stress, and bears an N-terminal C10XXC13 redox disulfide center that is oxidized in active Spx.The structure of mutant Spx(C10S) showed a change in the conformation of helix alpha4. Amino acid substitutions R60E and K62E within and adjacent to helix alpha4 conferred defects in Spx-activated transcription but not Spx-dependent repression. Electrophoretic mobility-shift assays showed alphaCTD interaction with trxB promoter DNA, but addition of Spx generated a supershifted complex that was disrupted in the presence of reductant (DTT). Interaction of alphaCTD/Spx complex with promoter DNA required the cis-acting elements -45AGCA-42 and -34AGCG-31 of the trxB promoter. The Spx(G52R) mutant, defective in alphaCTD binding, did not interact with the alphaCTD-trxB complex. Spx(R60E) not only failed to complex with alphaCTD-trxB, but also disrupted alphaCTD-trxB DNA interaction.The results show that Spx and alphaCTD form a complex that recognizes the promoter DNA of an Spx-controlled gene. A conformational change during oxidation of Spx to the disulfide form likely alters the structure of Spx alpha helix alpha4, which contains residues that function in transcriptional activation and alphaCTD/Spx-promoter interaction. The results suggest that one of these residues, R60 of the alpha4 region of oxidized Spx, functions in alphaCTD/Spx-promoter contact but not in alphaCTD interaction