81,793 research outputs found
Anti-Poverty Strategies for the UK: Poverty and Crime Review
This review of the literature about how and why poverty and crime influence one another, and the benefits to crime reduction of reducing poverty, looks at the implications for practical policies and strategies
Myxoid Neurothekeoma of the Nipple
Neurothekeomas are rare benign cutaneous neoplasms of nerve sheath origin. They are primarily found in the superficial soft tissue and are also known as dermal nerve sheath myxomas. They are commonly found on the upper extremities, head and neck followed by trunk. Here is an unusual presentation of neurothekeoma occurring as a polypoidal lesion of the nipple in a young female patient
Primary Cutaneous Low Grade Mucinous Adenocarcinoma of Eyelid
Primary cutaneous mucinous adenocarcinoma is a rare adnexal neoplasm, eyelid being the most common site of presentation. Clinically it is mistaken for a benign / cystic lesion. Its morphologic similarity to metastatic deposits from breast, gastrointestinal tract (GIT) or any visceral sites adds to the diagnostic difficulty mandating the role of ancillary techniques in precise diagnosis and hence planning the management. We report a case of primary cutaneous mucinous adenocarcinoma of eyelid with emphasis on pathology along with a brief review of literature
Study addiction - a new area of psychological study: conceptualization, assessment, and preliminary empirical findings
Aims: Recent research has suggested that for some individuals, educational studying may become compulsive and excessive and lead to ‘study addiction’. The present study conceptualized and assessed study addiction within the framework of workaholism, defining it as compulsive over-involvement in studying that interferes with functioning in other domains and that is detrimental for individuals and/or their environment. Methods: The Bergen Study Addiction Scale (BStAS) was tested - reflecting seven core addiction symptoms (salience, mood modification, tolerance, withdrawal, conflict, relapse, and problems) - related to studying. The scale was administered via a cross-sectional survey distributed to Norwegian (n = 218) and Polish (n = 993) students with additional questions concerning demographic variables, study-related variables, health, and personality. Results: A one-factor solution had acceptable fit with the data in both samples and the scale demonstrated good reliability. Scores on BStAS converged with scores on learning engagement. Study addiction (BStAS) was significantly related to specific aspects of studying (longer learning time, lower academic performance), personality traits (higher neuroticism and conscientiousness, lower extroversion), and negative health-related factors (impaired general health, decreased quality of life and sleep quality, higher perceived stress). Conclusions: It is concluded that BStAS has good psychometric properties, making it a promising tool in the assessment of study addiction. Study addiction is related in predictable ways to personality and health variables, as predicted from contemporary workaholism theory and research
Symbolic Quantitative Information Flow
acmid: 2382791 issue_date: November 2012 keywords: algorithms, security, verification numpages: 5acmid: 2382791 issue_date: November 2012 keywords: algorithms, security, verification numpages: 5acmid: 2382791 issue_date: November 2012 keywords: algorithms, security, verification numpages: 5acmid: 2382791 issue_date: November 2012 keywords: algorithms, security, verification numpages: 5acmid: 2382791 issue_date: November 2012 keywords: algorithms, security, verification numpages:
The Evolution of Altruism in Spatially Structured Populations
The evolution of altruism in humans is still an unresolved puzzle. Helping other individuals is often kinship-based or reciprocal. Several examples show, however, that altruism goes beyond kinship and reciprocity and people are willing to support unrelated others even when this is at a cost and they receive nothing in exchange. Here we examine the evolution of this "pure" altruism with a focus on altruistic teaching. Teaching is modeled as a knowledge transfer which enhances the survival chances of the recipient, but reduces the reproductive efficiency of the provider. In an agent-based simulation we compare evolutionary success of genotypes that have willingness to teach with those who do not in two different scenarios: random matching of individuals and spatially structured populations. We show that if teaching ability is combined with an ability to learn and individuals encounter each other on a spatial proximity basis, altruistic teaching will attain evolutionary success in the population. Settlement of the population and accumulation of knowledge are emerging side-products of the evolution of altruism. In addition, in large populations our simple model also produces a counterintuitive result that increasing the value of knowledge keeps fewer altruists alive.Altruism, Teaching, Knowledge Transfer, Spatially Structured Social Dilemmas
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The thermodynamics of metabolism, cardiovascular performance and exercise, in health and diabetes: The objective of clinical markers
Extensive experience in UK National Health Service metabolic syndrome/type 2 diabetes clinics highlights the need for convenient clinical marker(s) which can be readily used to indicate the success or otherwise of alternative therapies. In this paper we study the metabolic context of the healthy and diseased states, which points to the haemodynamics being a possible key in identifying candidate markers. Human metabolism relates to two elemental thermodynamic systems, the individual cell and the human body in its entirety. The fundamental laws of thermodynamics apply to humans, animals, and their individual cells for both healthy and diseased conditions. as they are to classic heat engines. In compliance with the second law enhanced levels of heat are generated under exercise, heat itself being another factor modulating the cardiovascular response to physical exercise. Nutrients and oxygen uptake occurs via the digestive system and lungs, respectively, leading to ATP production by the established metabolic pathways: this is controlled by insulin. These are then delivered to the cells via the haemodynamic system to satisfy local metabolic need. The supply and demand of oxygen are finely regulated, in part, via oxygen-dependent release of ATP from the circulating erythrocytes. Energy supply and demand are regulated to sustain muscle activity resulting in the body’s output of measurable thermodynamic work—i.e. exercise. Recently a dynamic pathway model allowing quantification of ATP release from the erythrocytes and its contribution to oxygen supply regulation has been published. However, metabolic uptake is well known to be greatly affected by disease such as the highly prevalent diabetes type 2 with insulin resistance and beta cell dysfunction having mechanistic roles. In 2010, over 25% of residents above 65 in the USA had diabetes 2. The complexity of the metabolic pathways means that monitoring of patient-specific treatment would be beneficial from a diabetic marker which may be haemodynamic-related and traceable via the local fluid dynamics
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