Concomitant use of statins and s-(2-boron-ethyl)-l-cysteine arginase inhibitor to correct endotoxin-induced endothelial dysfunction

The concomitant use of non-selective S-(2-boron-ethyl)-L-cysteine (BEC) arginase inhibitor with simvastatin, atorvastatin, rosuvastatin and nanoparticulated rosuvastatin on the background of endotoxin-induced disorder modeling by Staphylococcus aureus (strain 13407) injection under the skin – 60 billions of microbial bodies – exhibits an endothelium- and cardioprotective action which is evident as endothelial dysfunction factor (EDF) increase prevention, adrenoreactivity, maintenance of myocardial reserve, and normalization of biochemical markers (total NO, expression of eNOS, C-reactive protein, IL-6, tumor necrosis factor

ОПТИЧЕСКИЕ СВОЙСТВА ТОНКИХ ПЛЕНОК ZnO+10 % ITO НА ПОДЛОЖКАХ АНОДНОГО ОКСИДА АЛЮМИНИЯ

ZnO thin films of zinc oxide doped with 10 % ITO (indium tin oxide) on anodic aluminum oxide substrates are formed in vacuum during high-frequency repetitively pulsed laser deposition. The morphology of films on porous and non-porous surfaces of substrates was studied by atomic force microscopy. The optical properties of the films in the visible, near, and middle IR regions of the electromagnetic radiation spectrum, the Raman spectra, and also the features of the photoluminescence characteristics have been experimentally investigated. Zinc oxide films can be used in optoelectronic transducers, as luminescent material, in the form of transparent electrodes, sensitive layers of gas and biological sensors, catalysts, X-ray and gamma-radiation detectors.Тонкие пленки оксида цинка ZnO, легированные 10 % ITO (оксидом индия-олова), на подложках из анодного оксида алюминия сформированы в вакууме при высокочастотном импульснопериодическом лазерном осаждении. Методом атомно-силовой микроскопии изучены морфологии пленок на пористой и беспористой поверхностях подложек. Экспериментально исследованы оптические свойства пленок в видимой, ближней и средней инфракрасных областях спектра электромагнитного излучения, спектры комбинационного рассеяния, а также особенности фотолюминесцентных характеристик. Пленки оксида цинка могут быть использованы в оптоэлектронных преобразователях как люминесцентный материал, в виде прозрачных электродов, чувствительных слоев газовых и биологических сенсоров, катализаторов, детекторов рентгеновского и гамма-излучений

Concomitant use of statins and s-(2-boron-ethyl)-l-cysteine arginase inhibitor to correct endotoxin-induced endothelial dysfunction

The concomitant use of non-selective S-(2-boron-ethyl)-L-cysteine (BEC) arginase inhibitor with simvastatin, atorvastatin, rosuvastatin and nanoparticulated rosuvastatin on the background of endotoxin-induced disorder modeling by Staphylococcus aureus (strain 13407) injection under the skin – 60 billions of microbial bodies – exhibits an endothelium- and cardioprotective action which is evident as endothelial dysfunction factor (EDF) increase prevention, adrenoreactivity, maintenance of myocardial reserve, and normalization of biochemical markers (total NO, expression of eNOS, C-reactive protein, IL-6, tumor necrosis factor

Definition of adequate model for knowledge representation in modern information systems

The article summarizes limitations of relational database approach in modern informational systems. Analysis is made based on main distinctive features of knowledge that is processed by modern informational systems. Non-relational data models such as frames, object model and ontology are considered as alternatives to relational approach in regard to defined particularities. As result, rules are defined for choosing the adequate data model to be used in modern informational systems.Обоснована ограниченность реляционной модели данных для использования современными информационными системами. Определены основные особенности знаний, которые присущи современным информационным системам. Проанализированы нереляционные модели данных, такие как фреймы, объектные модели, онтологические модели с точки зрения отображения особенностей знаний. Определена адекватная модель данных для задач, решаемых информационными системами

Optical properties of thin films ZNO+10 % ITO on the substrate of anodic aluminum oxide

ZnO thin films of zinc oxide doped with 10 % ITO (indium tin oxide) on anodic aluminum oxide substrates are formed in vacuum during high-frequency repetitively pulsed laser deposition. The morphology of films on porous and non-porous surfaces of substrates was studied by atomic force microscopy. The optical properties of the films in the visible, near, and middle IR regions of the electromagnetic radiation spectrum, the Raman spectra, and also the features of the photoluminescence characteristics have been experimentally investigated. Zinc oxide films can be used in optoelectronic transducers, as luminescent material, in the form of transparent electrodes, sensitive layers of gas and biological sensors, catalysts, X-ray and gamma-radiation detectors

Open access for operational research publications from low- and middle-income countries:who pays?

Open-access journal publications aim to ensure that new knowledge is widely disseminated and made freely accessible in a timely manner so that it can be used to improve people's health, particularly those in low- and middle-income countries. In this paper, we briefly explain the differences between closed- and open-access journals, including the evolving idea of the ‘open-access spectrum’. We highlight the potential benefits of supporting open access for operational research, and discuss the conundrum and ways forward as regards who pays for open access

Optical properties of thin films ZNO+10 % ITO on the substrate of anodic aluminum oxide

Тонкие пленки оксида цинка ZnO, легированные 10 % ITO (оксидом индия-олова), на подложках из анодного оксида алюминия сформированы в вакууме при высокочастотном импульсно- периодическом лазерном осаждении. Методом атомно-силовой микроскопии изучены морфологии пленок на пористой и беспористой поверхностях подложек. Экспериментально исследованы оптические свойства пленок в видимой, ближней и средней инфракрасных областях спектра электромагнитного излучения, спектры комбинационного рассеяния, а также особенности фотолюминесцентных характеристик. Пленки оксида цинка могут быть использованы в оптоэлектронных преобразователях как люминесцентный материал, в виде прозрачных электродов, чувствительных слоев газовых и биологических сенсоров, катализаторов, детекторов рентгеновского и гамма-излучений. ZnO thin films of zinc oxide doped with 10 % ITO (indium tin oxide) on anodic aluminum oxide substrates are formed in vacuum during high-frequency repetitively pulsed laser deposition. The morphology of films on porous and non-porous surfaces of substrates was studied by atomic force microscopy. The optical properties of the films in the visible, near, and middle IR regions of the electromagnetic radiation spectrum, the Raman spectra, and also the features of the photoluminescence characteristics have been experimentally investigated. Zinc oxide films can be used in optoelectronic transducers, as luminescent material, in the form of transparent electrodes, sensitive layers of gas and biological sensors, catalysts, X-ray and gamma-radiation detectors