35 research outputs found

    Promoting Value Practice in Museums Creates Impact

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    This article examines how museological value discussion can offer a tool for museum professionals to engage themselves in the current discourse regarding building sustainable futures. The focus of the article is on collection care and collection development. It describes the latest interview and workshop results regarding museum values in the field of collection development among Finnish museum professionals and students. In addition, it emphasizes the integration of theoretical knowledge and its practical application. Promoting and creating opportunities for value discussion among museum professionals increases the ability of these professionals to further engage in such value-related discourse with various stakeholders. Eventually, the benefits of this kind of value-based discussions are to be seen in the more coherent and focused ones regarding museological values between and among various parties, be they museum professionals, politicians, students or museum visitors. The initial idea for the interviews, and subsequently the workshops as well, emerged from a collection development survey conducted in 2012 among Finnish art museums, which was published in 2016 by the author. Based on the material analyzed at that time, it became clear that the issue of active values in Finnish museums would need further study.Peer reviewe

    Exposure to dietary ochratoxin in Egypt and Hong Kong

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    Conference Theme: Nutrition Security for AllPoster Presentation: no. P152-04Ochratoxin A (OTA) is a mycotoxin with worldwide occurrence in a variet of foods and feeds. This carcinogenic and teratogenic mycotoxin has been linked to human endemic nephro…link_to_OA_fulltex

    Occurrence of teratogenic ochratoxin A in blood sample of Egyptian women at child bearing age

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    The Conference program's website is located at https://www.grc.org/programs.aspx?year=2009&program=mycotoxin

    Lactobacillus rhamnosus strain GG restores alkaline phosphatase activity in differentiating Caco-2 cells dosed with the potent mycotoxin deoxynivalenol

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    Deoxynivalenol (DON) contamination of cereal crops occurs frequently, and may cause acute exposure at high levels or chronic more moderate exposure. DON has proven toxicity including restriction of enterocyte differentiation, which may play a part in DON induced gastroenteritis. The probiotic bacteria Lactobacillus rhamnosus strain GG (GG) can bind DON, and therefore potentially restrict bioavailability of this toxin. Binding efficacy is not significantly altered by heat treatment, and therefore this in vitro study evaluated whether heat inactivated GG could restore the differentiation process in Caco-2 cells, using alkaline phosphatase (ALP) activity as a marker of differentiation. DON (200 ng/mL) caused a significant (p 0.9), 1 × 107 (p < 0.001), and 1 × 1010 CFU/mL (p < 0.001), respectively). Co-incubation of the non-binding strain, LC-705 (1 × 1010 CFU/mL), with DON did not significantly restore the ALP (1841 ± 97 U/mg, p < 0.077) compared to DON only treated cells. When viable GG were co-incubated with DON a similar restoration of ALP activity was observed as seen for heat inactivated GG. These combined data suggest that the major effect of GG on restoring ALP activity, and therefore Caco-2 cell differentiation, was due to specific binding of DON, with possibly a more minor role of non-specific bacterial interference. © 2008 Elsevier Ltd. All rights reserved.link_to_subscribed_fulltex

    Characterisation of aflatoxin and deoxynivalenol exposure among pregnant Egyptian women

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    Mycotoxins such as the aflatoxins and deoxynivalenol (DON) are frequent contaminants of food. Aflatoxin B1 (AFB1) and DON affect the immune system and restrict growth; additionally AFB1 is carcinogenic. To date there are limited descriptive biomarker data concerning maternal exposures during pregnancy, and none on co-exposures to these mycotoxins. This survey was a cross-sectional assessment providing descriptive data on the concentrations of serum aflatoxin-albumin (AF-alb), urinary aflatoxin M1 (AFM1), and urinary DON for 98 pregnant women from Egypt, in relation to diet and socioeconomic status, during the third trimester. AF-alb was detected in 34 of 98 (35%) samples, geometric mean (GM) of positives = 4.9 pg AF-lys mg -1 albumin (95% confidence interval (CI) = 4.1-5.8 pg mg -1), and AFM1 in 44 of 93 (48%) samples, GM of positives = 19.7 pg mg -1 creatinine (95%CI = 14.8-26.3 pg mg -1). AF-alb and AFM1 levels were positively correlated (R = 0.276, p = 0.007). DON was detected in 63 of 93 (68%), GM of positives = 2.8 ng mg -1 (95%CI = 2.1-3.6 ng mg -1). Aflatoxin and DON biomarkers were observed in 41% of the subjects concurrently. The frequency and level of these biomarkers in Egyptian women were modest compared with known high-risk countries. However, this study represents the first biomarker survey to report on the occurrence of DON biomarkers in an African population, in addition to the co-occurrence of these two potent mycotoxins. This combined exposure may be of particular concern during pregnancy given the potential of toxin transfer to the foetus. © 2012 Copyright Taylor and Francis Group, LLC.link_to_subscribed_fulltex
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