Efficient and direct iodination of alkyl benzenes using polymer/HIO4 and I2 under mild condition

An efficient and rapid method has been found for the iodination of aromatic compounds using iodine and polymer-supported periodic acid (PSPIA) as an oxidant under mild aprotic conditions. The reagent after the completion of the reaction was easily removed by filtration and was regenerated for further use. This method has some advantages such as: mild reaction conditions, straight forward procedure, inexpensive method, high yields and one-pot conversion. KEY WORDS: Iodine, Polymer-supported periodic acid, Oxidant, Iodination Bull. Chem. Soc. Ethiop. 2014, 28(2), 305-308.   DOI: http://dx.doi.org/10.4314/bcse.v28i2.1

Reference Values of Oxidative Stress Parameters in Adult Iranian Fat-Tailed Sheep

The present study was performed on 111 adult clinically healthy Iranian fat-tailed sheep from both sexes (28 male and 83 female). Blood concentrations of oxidative stress parameters viz. malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) were determined. The reference values for oxidative stress parameters of adult clinically healthy Iranian fat-tailed sheep were as followed: MDA 0.53-0.60 mmol/l, SOD 948.65-1011.50 U/gHb, CAT 1834.29-1915.63 U/gHb and GPX 191.67-196.52 U/gHb. There were no significant differences in oxidative stress parameters among animal of the two sexes

A Study of Correlation of Serum Leptin with Trace Elements in Water Buffalo (Bubalus bubalis)

The present study was designed to evaluate the correlations of the serum leptin with trace elements in water buffalo (Bubalus bubalis). The serum concentration of leptin and its correlations with serum concentrations of copper, zinc, selenium, iron and manganese were measured in 80 clinically healthy water buffaloes. The serum concentration of leptin had no significant correlation with the measured trace elements (P>0.05). Separate evaluation of the age groups also showed no significant difference between age groups and no significant correlation between serum leptin and the measured trace elements. In male buffaloes, the serum concentration of leptin had a significant correlation with the zinc/copper ratio (r= 0.53, P=0.014). These relationships were not measured in water buffalo previously and were partially different from those of other species

Kokcidioza koza: učinci pokusne infekcije na određene krvne pokazatelje.

The objective of this experiment was to elucidate the aspects of differential circulatory cell responses during experimental coccidiosis in goat. A total of twenty newborn kids were selected; ten of them were infected with sporulated oocysts of the most pathogenic species of Eimeria and the remainder served as control. Blood samples were taken at 0 (before inoculation), 3, 7, 14, 17, 21, 24, 28 and 35 days post infection (dpi) and some hematological and fecal related parameters were measured. According to our data, except for a significant decrease at 24 dpi, packed cell volume (PCV) and hemoglobin (Hb) concentrations evidenced no substantial changes in the infected kids compared to controls. The percentage of the circulatory neutrophils showed remarkable increases from 7 to 24 dpi. Unlike neutrophils, the level of lymphocytes represented marked decreases from 7 to 24 dpi. In addition, circulatory eosinophils evidenced no statistical changes during the infection; however monocytes revealed a significant elevation only at 17 and 24 dpi. Substantial activations of neutrophils and lymphocytes indicate that these cells have key roles in either preventing or establishing primary infections with Eimeria in goats.Cilj pokusa bio je rasvijetliti različite odgovore stanica u krvnom optjecaju tijekom pokusno uzrokovane kokcidioze u koza. U pokus je bilo uključeno 20 novoojarene jaradi od čega je 10 bilo zaraženo sporuliranim oocistama najpatogenije vrste roda Eimeria, a ostalih 10 su poslužili za kontrolu. Uzorci njihove krvi bili su uzeti 0. (prije zaražavanja), 3., 7., 14., 17., 21., 24., 28. i 35. dana nakon zaražavanja te su bili pretraženi na neke hematološke pokazatelje. Parazitološki su bili pretraženi i uzorci izmeta. Vrijednosti hematokrita i koncentracije hemoglobina nisu pokazivale bitne promjene u zaraženih u odnosu na kontrolne životinje, osim značajnog smanjenja 24. dana nakon infekcije. Postotak optjecajnih neutrofila bio je značajno povećan od 7. do 24. dana nakon infekcije. Za razliku od neutrofila, razina limfocita bila je znantno smanjena od 7. do 24. dana poslije infekcije. Povrh toga, statistički značajne promjene ustanovljene su u broju optjecajnih eozinofila dok je broj monocita bio značajno povišen 17. i 24. dana nakon infekcije. Znatna aktivacija neutrofila i limfocita upućuju na zaključak da te stanice imaju ključnu ulogu u sprječavanju primarne infekcije kokcidijama roda Eimeria u koza

Relationships Between Thyroid Hormones, Serum Trace Elements and Erythrocyte Antioxidant Enzymes in Goats

Thyroid hormones might be able to regulate the activities of superoxide dismutase (SOD), catalase and glutathione peroxidase (GPX) enzymes. The role of thyroid hormones in metabolic pathways and antioxidant enzyme activities are well known in many species. Nevertheless, there is no report describing probable relationship between thyroid hormones status, erythrocyte antioxidant enzymes and serum profiles of trace elements. This study was undertaken to investigate the relationship between these parameters in Iranian native goats. Blood samples were taken from the jugular vein of 50 clinically healthy Iranian native goats under aseptic conditions during 6 consecutive days of summer. The serum was analyzed for serum profile of thyroid hormones, trace elements, SOD and GPX activity. There were no significant differences in serum thyroid hormones, serum levels of zinc (Zn), copper (Cu), manganese (Mn), iron (Fe), selenium (Se) and antioxidant enzymes on different days (P>0.05). There were significant correlations between triiodothyronine (T3) and GPX (P<0.05; r=0.203) and thyroxine (T4) and GPX (P<0.05; r=0.312). There was no significant correlation between other parameters

The Effect of Intrauterine Cephapirin on Treatment of Endometritis in Commercial Dairy Cattle

Summary To evaluate the effect of intrauterine cephapirin on treatment of endometritis 39 Holstein dairy cows that affected with postpartum endometritis were selected and randomly assigned to two experimental designs. In experiment 1, 6 out of 14 cows were 25 to 30 days after parturition were treated by intrauterine oxytetracycline. Another 8 cows were treated by intrauterine cephapirin (Metri-Care). In experiment 2, 25 cows that were 55-60 days after parturition received three types of treatment. 6 cows were received only PGF2α, 9 cows were received PGF2α and procaine penicillin G, and 10 cows were treated by intrauterine Metri-Care. Cervical mucosa was collected before and after each treatment. There was no significant difference between mean (±SD) of neutrophils before and 14 days after treatment with them. Conception rates of cows received oxytetracycline and Metri-Care were 66.66% (4/6) and 37.5% (3/8), respectively. There was significant difference between mean of neutrophils before and 14 days after treatment at all groups. Conception rate of cows received only PGF2α was 33.33 % (2/6) and in cows received penicillin and PGF2α was 55.55% (5/9) but in cows received MetriCare was 90.0% (9/10). Therefore, Metri-care may be good choice for treatment of postpartum uterine infection in cow

Serum profiles of calcium, phosphorus, magnesium, vitamin D and parathyroid hormone in Caspian horses during different seasons

Minerals play an essential role in the normal vital process. Calcium, phosphorus and magnesium are the most abundant minerals. Vitamin D and parathyroid hormone play a key role in regulation of their homeostasis as well. The aim of this study was to evaluate calcium, phosphorus, magnesium, vitamin D and parathyroid hormone on 30 Caspian horses of Guilan Province (south of the Caspian Sea) in two different seasons. So that, 15 stallions and 15 mares were sampled at the age groups ≤ 3 years and > 3 years, respectively. Fasting blood samples were collected twice, in August and January 2015 from jugular vein of horses. Serum calcium, phosphorus and magnesium were measured by colorimetric methods, while 25(OH)D3 and parathyroid hormone were measured by ELISA. The calcium (11.50 vs. 14.25 mg dL-1 ), magnesium (2.13 vs. 3.72 mg dL-1 ) and vitamin D (1.66 vs. 2.48 ng mL-1 ) levels were lower in winter than in summer (P < 0.05). The Caspian horses had higher phosphorus (4.52 vs. 3.26 mg dL-1 ) in winter than in summer (P < 0.05). Effect of sex on the measured parameters was not significant. Effects of age on the calcium, magnesium, vitamin D and parathyroid hormone levels were not significant, but ≤ 3 year - old horses had higher phosphorus (4.63 vs. 3.15 mg dL-1 ) than > 3 year - old ones (P < 0.05). The vitamin D level of mares was higher (3.10 vs. 1.43 ng mL-1 ) in summer than in winter (P < 0.05). Effects of sex, season, age and their interactions on parathyroid hormone were not significant. In conclusion, calcium, phosphorus, magnesium and parathyroid hormone levels in Caspian horses were within their physiological range, but vitamin D was low without any signs of deficiency. The Caspian horses had lower calcium, magnesium and vitamin D levels in winter than in summer

Cyanobacterial metabolites as a source of sunscreens and moisturizers: a comparison with current synthetic compounds

The recognition of the harmful effects of ultraviolet radiation on the skin has led to the commercial development of inorganic and synthetic organic UV filters that can attenuate the negative effects of sunlight exposure. In addition, chemical moisturizers are extensively used in cosmetic products to improve the ability of skin to retain water. Whilst these chemicals have clear beneficial qualities, they may also have adverse effects such as contact sensitivity, oestrogenicity and even tumorigenic effects on human skin. Furthermore, the accumulation of such chemicals in the aquatic environment could be potentially harmful. Consequently, there is interest in exploiting safer alternatives derived from biological sources, especially from photosynthetic organisms such as cyanobacteria that have developed mechanisms for coping with high UV irradiation and desiccation. In order to overcome the detrimental effects of UV radiation, these microorganisms produce UV screening compounds such as mycosporine-like amino acids and scytonemin, which are good candidates as alternatives to current synthetic UV filters. In addition, extracellular substances produced by some extremophilic species living in hyper-arid habitats have a high water retention capacity and could be used in cosmetic products as moisturizers. In this review, we present an overview of the literature describing the potential of cyanobacterial metabolites as an alternative source for sunscreens and moisturizers

Serum acute phase proteins in cows with SARA (Subacute Ruminal Acidosis) suspect

The aim of this study was to evaluate the variations of Acute Phase Proteins (APPs) and other blood constituents during the onset of the sub-acute ruminal acidosis (SARA) pathological status. A total of 108 cows from 12 dairy herds were randomly selected and divided into three Groups of 36 animals each. All animals were subjected to a rumenocentesis. Group A was composed by subjects with a rumen pH>5.8, Group B was composed by subjects with a rumen pH ≤5.5≤5.8 and Group C was composed by subjects with a rumen pH<5.5. Blood samples were collected by jugular venipuncture and Haptoglobin (Hp), Serum Amyloid A (SAA), Total Proteins, Albumin and White Blood Cells (WBC) were determined. One-way ANOVA showed a statistical significance on Rumen pH, Hp, SAA. SARA seems not stimulate the APPs production from liver