HPC Cloud for Scientific and Business Applications: Taxonomy, Vision, and Research Challenges

High Performance Computing (HPC) clouds are becoming an alternative to on-premise clusters for executing scientific applications and business analytics services. Most research efforts in HPC cloud aim to understand the cost-benefit of moving resource-intensive applications from on-premise environments to public cloud platforms. Industry trends show hybrid environments are the natural path to get the best of the on-premise and cloud resources---steady (and sensitive) workloads can run on on-premise resources and peak demand can leverage remote resources in a pay-as-you-go manner. Nevertheless, there are plenty of questions to be answered in HPC cloud, which range from how to extract the best performance of an unknown underlying platform to what services are essential to make its usage easier. Moreover, the discussion on the right pricing and contractual models to fit small and large users is relevant for the sustainability of HPC clouds. This paper brings a survey and taxonomy of efforts in HPC cloud and a vision on what we believe is ahead of us, including a set of research challenges that, once tackled, can help advance businesses and scientific discoveries. This becomes particularly relevant due to the fast increasing wave of new HPC applications coming from big data and artificial intelligence.Comment: 29 pages, 5 figures, Published in ACM Computing Surveys (CSUR

BlockGov: Blockchain-Based Data Governance in the Internet of Things using Smart Contracts

The rapid growth and integration of the Internet of Things (IoT) emphasizes the crucial need for effective data governance. This research unveils a novel framework, capitalizing on blockchain and smart contracts, aimed at decentralizing data governance in the IoT sphere. Our approach allows stakeholders to formulate and enforce data governance collaboratively, ensuring a balance between transparency, adaptability, and flexibility. Using the Ethereum platform and Solidity as our smart contract language, we constructed a demonstrative proof-of-concept. Our comparative evaluations highlighted our system's superiority, outpacing previous works with a scalability score of 95%, flexibility at 90%, and an unmatched transparency score of 100%. This framework presents a transformative paradigm for organizations and individuals working with IoT data, offering an efficient, transparent, and robust data governance mechanism

Secure Digital Information Forward Using Highly Developed AES Techniques in Cloud Computing

Nowadays, in communications, the main criteria are ensuring the digital information and communication in the network. The normal two users' communication exchanges confidential data and files via the web. Secure data communication is the most crucial problem for message transmission networks. To resolve this problem, cryptography uses mathematical encryption and decryption data on adaptation by converting data from a key into an unreadable format. Cryptography provides a method for performing the transmission of confidential or secure communication. The proposed AES (Advanced Encryption Standard)-based Padding Key Encryption (PKE) algorithm encrypts the Data; it generates the secret key in an unreadable format. The receiver decrypts the data using the private key in a readable format. In the proposed PKE algorithm, the sender sends data into plain Text to cypher-text using a secret key to the authorized person; the unauthorized person cannot access the data through the Internet; only an authorized person can view the data through the private key. A method for identifying user groups was developed. Support vector machines (SVM) were used in user behaviour analysis to estimate probability densities so that each user could be predicted to launch applications and sessions independently. The results of the proposed simulation offer a high level of security for transmitting sensitive data or files to recipients compared to other previous methods and user behaviour analysis

காலநிலை மாற்றத்தைக் கட்டுப்படுத்துவதில் சமூகத்தின் பங்கு (ClimEd Series:3D)

காலநிலை மாற்றத்தைக் கட்டுப்படுத்துவதில் சமூகத்தின் பங்கு (ClimEd Series:3D

Exposure to Household Air Pollution from Biomass-Burning Cookstoves and HbA1c and Diabetic Status Among Honduran Women

Household air pollution from biomass cookstoves is estimated to be responsible for more than two and a half million premature deaths annually, primarily in low and middle‐income countries where cardiometabolic disorders, such as Type II Diabetes, are increasing. Growing evidence supports a link between ambient air pollution and diabetes, but evidence for household air pollution is limited. This cross‐sectional study of 142 women (72 with traditional stoves and 70 with cleaner‐burning Justa stoves) in rural Honduras evaluated the association of exposure to household air pollution (stove type, 24‐hour average kitchen and personal fine particulate matter [PM2.5] mass and black carbon) with glycated hemoglobin (HbA1c) levels and diabetic status based on HbA1c levels. The prevalence ratio (PR) per interquartile range increase in pollution concentration indicated higher prevalence of prediabetes/diabetes (vs normal HbA1c) for all pollutant measures (eg, PR per 84 μg/m3 increase in personal PM2.5, 1.49; 95% confidence interval [CI], 1.11‐2.01). Results for HbA1c as a continuous variable were generally in the hypothesized direction. These results provide some evidence linking household air pollution with the prevalence of prediabetes/diabetes, and, if confirmed, suggest that the global public health impact of household air pollution may be broader than currently estimated

Organization and Running of the First Comprehensive Hereditary Cancer Clinic in India

Hereditary cancers are thought to account for around 5% of cancers, particularly breast/ovarian and colorectal cancers. In India there is a paucity of data on hereditary cancers and the mutations in some of the common genes linked to hereditary cancers, such as BRCA1, BRCA2, hMSH2 and hMLH1. The country's first comprehensive hereditary cancer clinic was established in February 2002. The article describes the organization and running of the Clinic. It also discusses some of the social issues relevant to the given population in running the Hereditary Cancer Clinic

Outcome with lenalidomide plus dexamethasone followed by early autologous stem cell transplantation in patients with newly diagnosed multiple myeloma on the ECOG-ACRIN E4A03 randomized clinical trial: long-term follow-up

In Eastern Cooperative Oncology Group-ACRIN E4A03, on completion of four cycles of therapy, newly diagnosed multiple myeloma patients had the option of proceeding to autologous peripheral blood stem cell transplant (ASCT) or continuing on their assigned therapy lenalidomide plus low-dose dexamethasone (Ld) or lenalidomide plus high-dose dexamethasone (LD). This landmark analysis compared the outcome of 431 patients surviving their first four cycles of therapy pursuing early ASCT to those continuing on their assigned therapy. Survival distributions were estimated using the Kaplan–Meier method and compared with log-rank test. Ninety patients (21%) opted for early ASCT. The 1-, 2-, 3-, 4- an

Tests & Calibration on Ultra Violet Imaging Telescope (UVIT)

Ultra Violet Imaging Telescope on ASTROSAT Satellite mission is a suite of Far Ultra Violet (FUV; 130 to 180 nm), Near Ultra Violet (NUV; 200 to 300 nm) and Visible band (VIS; 320 to 550nm) imagers. ASTROSAT is a first multi wavelength mission of INDIA. UVIT will image the selected regions of the sky simultaneously in three channels & observe young stars, galaxies, bright UV Sources. FOV in each of the 3 channels is about 28 arc-minute. Targeted angular resolution in the resulting UV images is better than 1.8 arc-second (better than 2.0 arc-second for the visible channel). Two identical co-aligned telescopes (T1, T2) of Ritchey-Chretien configuration (Primary mirror of 375 mm diameter) collect the celestial radiation and feed to the detector system via a selectable filter on a filter wheel mechanism; gratings are available in the filter wheels of FUV and NUV channels for slit-less low resolution spectroscopy. The detector system for each of the 3 channels is generically identical. One telescope images in the FUV channel, and other images in NUV and VIS channels. One time open-able mechanical cover on each telescope also works as Sun-shield after deployment.We will present the optical tests and calibrations done on the two telescopes. Results on vibrations test and thermo-vacuum tests on the engineering model will also be presented.Comment: 9 pages, 7 figures, to be published in Proc. SPIE 8443, "Space Telescopes and Instrumentation 2012: Ultraviolet to Gamma Ray