6,810 research outputs found
Controlling the neuronal balancing act: optical coactivation of excitation and inhibition in neuronal subdomains
Resource acquisition, distribution and end-use efficiencies and the growth of industrial society
A key feature of the growth of industrial society is the acquisition of increasing quantities of resources from the environment and their distribution for end use. With respect to energy, growth has been near exponential for the last 160 years. We attempt to show that the global distribution of resources that underpins this growth may be facilitated by the continual development and expansion of near optimal directed networks. If so, the distribution efficiencies of these networks must decline as they expand due to path lengths becoming longer and more tortuous. To maintain long-term exponential growth the physical limits placed on the distribution networks appear to be counteracted by innovations deployed elsewhere in the system: namely at the points of acquisition and end use. We postulate that the maintenance of growth at the specific rate of ~2.4% yr−1 stems from an implicit desire to optimise patterns of energy use over human working lifetimes
Differences between European birthweight standards: impact on classification of ‘small for gestational age’
We describe a quantitative and comparative review of a selection of European birthweight standards for gestational age for singletons, to enable appropriate choices to be made for clinical and research use. Differences between median values at term across standards in 10 regions and misclassification of ‘small for gestational age’ (SGA), were studied. Sex and parity differences, exclusion criteria, and methods of construction were considered. There was wide variation between countries in exclusion criteria, methods of calculating standards, and median birthweight at term. The lightest standards (e.g. France's medians are 255g lower than Norway's medians) were associated with fewer exclusion criteria. Up to 20% of the population used in the construction of the Scottish standard would be classified as SGA using the Norwegian standard. Substantial misclassification of SGA is possible. Assumptions about variation used in the construction of some standards were not justified. It is not possible to conclude that there are real differences in birthweight standards between European countries. Country-based standards control for some population features but add misclassification due to the differing ways in which standards are derived. Standards should be chosen to reflect clinical or research need. If standards stratified by sex or parity are not available, adjustments should be made. In multinational studies, comparisons should be made between results using both a common standard and country-based standards
A note on monopole moduli spaces
We discuss the structure of the framed moduli space of Bogomolny monopoles
for arbitrary symmetry breaking and extend the definition of its stratification
to the case of arbitrary compact Lie groups. We show that each stratum is a
union of submanifolds for which we conjecture that the natural metric is
hyperKahler. The dimensions of the strata and of these submanifolds are
calculated, and it is found that for the latter, the dimension is always a
multiple of four.Comment: 17 pages, LaTe
Facilitators and barriers to undertaking a constraint induced movement therapy (CIMT) protocol in sub-acute stroke: a synthesis of the literature
Therapists' perceptions of implementing constraint induced movement therapy: the enablers and barriers
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