Dynamic Considerations for Control of Closed Life Support Systems

Reliability of closed life support systems depend on their ability to continue supplying the crew's needs during perturbations and equipment failures. The dynamic considerations interact with the basic static design through the sizing of storages, the specification of excess capacities in processors, and the choice of system initial state. A very simple system flow model was used to examine the possibilities for system failures even when there is sufficient storage to buffer the immediate effects of the perturbation. Two control schemes are shown which have different dynamic consequences in response to component failures

Control and modeling of a CELSS (Controlled Ecological Life Support System)

Research topics that arise from the conceptualization of control for closed life support systems which are life support systems in which all or most of the mass is recycled are discussed. Modeling and control of uncertain and poorly defined systems, resource allocation in closed life support systems, and control structures or systems with delay and closure are emphasized

Globular Clusters and Dwarf Spheroidal Galaxies

Traditionally globular clusters and dwarf spheroidal galaxies have been distinguished by using one or more of the following criteria: (1) mass, (2) luminosity, (3) size, (4) mass-to-light ratio and (5) spread in metallicity. However, a few recently discovered objects show some overlap between the domains in parameter space that are occupied by galaxies and clusters. In the present note it is shown that ellipticity can, in some cases, be used to help distinguish between globular clusters and dwarf spheroidal galaxies.Comment: MNRAS (Letters), in pres

Association of mid-infrared solar plages with Calcium K line emissions and magnetic structures

Solar mid-IR observations in the 8-15 micrometer band continuum with moderate angular resolution (18 arcseconds) reveal the presence of bright structures surrounding sunspots. These plage-like features present good association with calcium CaII K1v plages and active region magnetograms. We describe a new optical setup with reflecting mirrors to produce solar images on the focal plane array of uncooled bolometers of a commercial camera preceded by germanium optics. First observations of a sunspot on September 11, 2006 show a mid-IR continuum plage exhibiting spatial distribution closely associated with CaII K1v line plage and magnetogram structures. The mid-IR continuum bright plage is about 140 K hotter than the neighboring photospheric regions, consistent with hot plasma confined by the magnetic spatial structures in and above the active regionComment: 5 pages, 4 figures. Accepted by PAS

Robotic control of the seven-degree-of-freedom NASA laboratory telerobotic manipulator

A computationally efficient robotic control scheme for the NASA Laboratory Telerobotic Manipulator (LTM) is presented. This scheme utilizes the redundancy of the seven-degree-of-freedom LTM to avoid joint limits and singularities. An analysis to determine singular configurations is presented. Performance criteria are determined based on the joint limits and singularity analysis. The control scheme is developed in the framework of resolved rate control using the gradient projection method, and it does not require the generalized inverse of the Jacobian. An efficient formulation for determining the joint velocities of the LTM is obtained. This control scheme is well suited for real-time implementation, which is essential if the end-effector trajectory is continuously modified based on sensory feedback. Implementation of this scheme on a Motorola 68020 VME bus-based controller of the LTM is in progress. Simulation results demonstrating the redundancy utilization in the robotic mode are presented

Noise sensitivity of sub- and supercritically bifurcating patterns with group velocities close to the convective-absolute instability

The influence of small additive noise on structure formation near a forwards and near an inverted bifurcation as described by a cubic and quintic Ginzburg Landau amplitude equation, respectively, is studied numerically for group velocities in the vicinity of the convective-absolute instability where the deterministic front dynamics would empty the system.Comment: 16 pages, 7 Postscript figure

Relation between Exercise Central Hemodynamic Load and Resting Cardiac Structure and Function in Young Men

Please view abstract in the attached PDF file

Charon's radius and density from the combined data sets of the 2005 July 11 occultation

The 2005 July 11 C313.2 stellar occultation by Charon was observed by three separate research groups, including our own, at observatories throughout South America. Here, the published timings from the three data sets have been combined to more accurately determine the mean radius of Charon: 606.0 +/- 1.5 km. Our analysis indicates that a slight oblateness in the body (0.006 +/- 0.003) best matches the data, with a confidence level of 86%. The oblateness has a pole position angle of 71.4 deg +/- 10.4 deg and is consistent with Charon's pole position angle of 67 deg. Charon's mean radius corresponds to a bulk density of 1.63 +/- 0.07 g/cm3, which is significantly less than Pluto's (1.92 +/- 0.12 g/cm3). This density differential favors an impact formation scenario for the system in which at least one of the impactors was differentiated. Finally, unexplained differences between chord timings measured at Cerro Pachon and the rest of the data set could be indicative of a depression as deep as 7 km on Charon's limb.Comment: 25 pages including 4 tables and 2 figures. Submitted to the Astronomical Journal on 2006 Feb 0

Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: Prospective observational study

OBJECTIVES: To characterize the clinical severity of covid-19 associated with the alpha, delta, and omicron SARS-CoV-2 variants among adults admitted to hospital and to compare the effectiveness of mRNA vaccines to prevent hospital admissions related to each variant. DESIGN: Case-control study. SETTING: 21 hospitals across the United States. PARTICIPANTS: 11 690 adults (≥18 years) admitted to hospital: 5728 with covid-19 (cases) and 5962 without covid-19 (controls). Patients were classified into SARS-CoV-2 variant groups based on viral whole genome sequencing, and, if sequencing did not reveal a lineage, by the predominant circulating variant at the time of hospital admission: alpha (11 March to 3 July 2021), delta (4 July to 25 December 2021), and omicron (26 December 2021 to 14 January 2022). MAIN OUTCOME MEASURES: Vaccine effectiveness calculated using a test negative design for mRNA vaccines to prevent covid-19 related hospital admissions by each variant (alpha, delta, omicron). Among patients admitted to hospital with covid-19, disease severity on the World Health Organization\u27s clinical progression scale was compared among variants using proportional odds regression. RESULTS: Effectiveness of the mRNA vaccines to prevent covid-19 associated hospital admissions was 85% (95% confidence interval 82% to 88%) for two vaccine doses against the alpha variant, 85% (83% to 87%) for two doses against the delta variant, 94% (92% to 95%) for three doses against the delta variant, 65% (51% to 75%) for two doses against the omicron variant; and 86% (77% to 91%) for three doses against the omicron variant. In-hospital mortality was 7.6% (81/1060) for alpha, 12.2% (461/3788) for delta, and 7.1% (40/565) for omicron. Among unvaccinated patients with covid-19 admitted to hospital, severity on the WHO clinical progression scale was higher for the delta versus alpha variant (adjusted proportional odds ratio 1.28, 95% confidence interval 1.11 to 1.46), and lower for the omicron versus delta variant (0.61, 0.49 to 0.77). Compared with unvaccinated patients, severity was lower for vaccinated patients for each variant, including alpha (adjusted proportional odds ratio 0.33, 0.23 to 0.49), delta (0.44, 0.37 to 0.51), and omicron (0.61, 0.44 to 0.85). CONCLUSIONS: mRNA vaccines were found to be highly effective in preventing covid-19 associated hospital admissions related to the alpha, delta, and omicron variants, but three vaccine doses were required to achieve protection against omicron similar to the protection that two doses provided against the delta and alpha variants. Among adults admitted to hospital with covid-19, the omicron variant was associated with less severe disease than the delta variant but still resulted in substantial morbidity and mortality. Vaccinated patients admitted to hospital with covid-19 had significantly lower disease severity than unvaccinated patients for all the variants