Waste management methods and sustainablity

© Springer International Publishing Switzerland 2015. Waste in its different forms is a significant environmental issue that receives a great deal of attention worldwide. Waste is generated as a result of production and consumption (domestic and industrial) activities and tends to increase with the level of prosperity and economic development of the country. Cost efficient, technology-based and sustainable management of both solid and liquid waste is crucial to economic growth and development of a healthy society in any given region. This chapter reviews traditional as well as modern approaches to solid waste management (SWM) and wastewater treatment. Sustainable methods of waste reduction, waste reuse and recycling are the preferred options when managing waste. There are many environmental benefits that can be derived from the use of these methods. They reduce or prevent greenhouse gas emissions, lessen the release of pollutants, conserve resources, save energy and minimise the demand for waste treatment technology and space. Establishment of sanitary landfills that meet standard hygienic requirements is the most widely adopted method of disposing of solid waste in developed countries. Vermicomposting and biogas technology produce reusable manure and combustible gas respectively from organic solid waste while waste-to-energy (incineration of waste) has quickly emerged as one of the most attractive renewable energy options. Wastewater if not properly disposed of, could be hazardous to human health and environment. Natural aquatic and terrestrial treatment systems with the environment-friendly designs and low-cost sanitation provide benefits for the reuse of water. Wise uses of aquatic and terrestrial plants are a means of several natural wastewater treatment methods. A decentralized wastewater treatment is being considered for most communities because of its economic and environmental advantages. Apart from natural treatment methods, membrane technology, nanotechnology, microbial fuel cells and electrocoagulation offer newer approaches to handling wastewater in a sustainable manner. The overall sustainable development ensures the path of reconciliation for society, environment, and economy in the long-term. People who generate waste, institutions who handle it and the local governance are key partners in an efficient waste management system. Need for education to create awareness on the importance of waste treatment and the sustainability aspects of the emerging technologies remains critical at all societal and governmental levels. Applications of information and communication technologies offer ingenious solutions to the problem of waste management

Monitoring bacterial diversity in a full-scale municipal wastewater treatment plant in dubai by fluorescence in situ hybridization technique

In this study, the bacterial diversity in the activated sludge system of a full-scale municipal wastewater treatment plant in Dubai was monitored over a period of one year using ribosomal RNA (rRNA) targeted oligonucleotide probes for a defined phylogenetic group of bacteria by the Fluorescence in situ hybridization (FISH) technique. The largest fraction of the bacterial community in the sludge samples belonged to the gamma-subgroup of proteobacteria (25%) followed by gram positive bacteria of high G+C content(16%), gram positive bacteria with low G+C content (9 %), beta-proteobacteria (8%) and alpha-proteobacteria (5 %) with respect to the population percentages stained by DAPI (4,6-diamino-2-phenylindole). A specific nocardioform actinomycete, simultaneously targeted by both HGC69a and MNP1 probes, was predominantly found throughout the study period in all activated sludge mixed liquor samples. The nocardioform actinomycetes group members were detected in both branched and single cell morphotypes. Most of the previously published genus and species specific probes failed to hybridize to the sludge samples. In conclusion, the overall bacterial community populations detected by the sub-group specific 16S rRNA targeted oligonucleotide probes in FISH technique remained almost constant throughout the period of study irrespective of treatment plant conditions

Quantum Dots: Application for the Detection of Salmonella typhimurium

Quantum dots (QDs) or nanocrystals 5 to 50 nm in size have recently emerged as a novel and promising class of fluorophores for cellular imaging. Unlike conventional organic dyes, QDs can be excited by a wide spectrum of wavelengths to give enhanced photostability, and their emission spectra, which differ according to size and material composition, are narrow, symmetrical, and tunable. This novel detection strategy can significantly improve the efficiency of molecular techniques used in the identification of important microbes related to human diseases. The aim of this study was to apply QDs linked antibodies to detect pathogenic Salmonella typhimurium cells. The signal, photostabilty and efficiency of QDs linked antibodies was compared with the organic fluorophore linked antibody for the detection of Salmonella cells. The use of QDs as fluorophores has shown greater enhancement in photostability and brighter signal than conven-tional organic dyes in detecting S. typhimurium cells. This approach might also be extended for the simultaneous detection of more than one pathogenic microorganism in the clinical, food or environmental samples by using specific antibodies linked with the QDs of different sizes and colors

An Ethanol-Based Proliposome Technology for Enhanced Delivery and Improved Respirability of Antiasthma Aerosols Generated Using a Micropump Vibrating-Mesh Nebulizer

Salbutamol sulphate liposomes were generated using ethanolbased proliposomes followed by nebulization using an Aeroneb Pro vibrating-mesh nebulizer. The droplet size, output and fine particle fraction (FPF) of the drug incorporated in liposome formulation were compared to those of a conventional drug solution. Aerosol output was determined gravimetrically and drug output was analyzed by using high performance liquid chromatography. The potential of aerosol deposition in deep lung was evaluated using inertial impaction and laser diffraction. The effect of formulation surface tension on the aerosol performance was studied. Output and FPF were improved using liposomes compared to the conventional solution, for instance, FPF values were 57.85% and 45.81% respectively. The volume median diameter as measured by laser diffraction was respectively 3.44 μm and 3.22 μm; however, the higher FPF of the liposome formulation is justified by the lower polydispersity of its aerosol. The improved aerosol performance using liposomes was attributed to the reduction of surface tension caused by the presence of phospholipid. This is the first study that demons trates the ability of liposomes to improve the nebulized drug output and FPF

Effect of poly(ethylene glycol) on insulin stability and cutaneous cell proliferation in vitro following cytoplasmic delivery of insulin-loaded nanoparticulate carriers – A potential topical wound management approach

We describe the development of a nanoparticulate system, with variation of poly(ethylene glycol) (PEG) content, capable of releasing therapeutic levels of bioactive insulin for extended periods of time. Recombinant human insulin was encapsulated in poly(d,l-lactide-co-glycolide) nanoparticles, manufactured with variation in poly(ethylene glycol) content, and shown to be stable for 6days using SDS-PAGE, western blot and MALDI MS. To determine if insulin released from this sustained release matrix could stimulate migration of cell types normally active in dermal repair, a model wound was simulated by scratching confluent cultures of human keratinocytes (HaCaT) and fibroblasts (Hs27). Although free insulin was shown to have proliferative effect, closure of in vitro scratch fissures was significantly faster following administration of nano-encapsulated insulin. This effect was more pronounced in HaCaT cells when compared to Hs27 cells. Variation in PEG content had the greatest effect on NP size, with a lesser influence on scratch closure times. Our work supports a particulate uptake mechanism that provides for intracellular insulin delivery, leading to enhanced cell proliferation. When placed into an appropriate topical delivery vehicle, such as a hydrogel, the extended and sustained topical administration of active insulin delivered from a nanoparticulate vehicle shows promise in promoting tissue healing

A systematic review and meta-analysis on the effect of neoadjuvant chemotherapy on complications following immediate breast reconstruction

Background The impact of neoadjuvant chemotherapy (NACT) on surgical outcomes following immediate breast reconstruction (IBR) remains unclear. While it is generally considered safe practice to perform an IBR post NACT, reported complication rates in published data are highly variable with the majority of studies including fewer than 50 patients in the NACT and IBR arm. To evaluate this further, we conducted a systematic review and meta-analysis on the effect of NACT on autologous and implant based immediate breast reconstructions. We aimed to assess for differences in the post-operative course following IBR between patients who received NACT with those who did not. Methods PubMed, EMBASE, and Cochrane Library were searched from 1995 to Sept 2, 2020 to identify articles that assessed the impact of NACT on IBR. All included studies assessed outcomes following IBR. Only studies comparing reconstructed patients receiving NACT to a control group of women who did not receive NACT were included. Unadjusted relative risk of outcomes between patients who received or did not receive NACT were synthesized using a fixed-effect meta-analysis. The evidence was assessed using the Newcastle Ottawa Scale scores and GRADE. Primary effect measures were risk ratios (RRs) with 95% confidence intervals. Results A total 17 studies comprising 3249 patients were included in the meta-analyses. Overall, NACT did not increase the risk of complications after immediate breast reconstructions (risk ratio [RR]: 0.91, 95% CI 0.74 to 1.11, p = 0.34). There was a moderate, but not significant, increase in flap loss following NACT compared with controls (RR: 1.23, 95% CI 0.70 to 2.18, p = 0.47; I2 = 0%). Most notably, there was a statistically significant increase in implant/expander loss after NACT (RR: 1.54, 95% CI 1.04 to 2.29, p = 0.03; I2 = 34%). NACT was not shown to significantly increase the incidence of hematomas, seromas or wound complications, or result in a significant delay to commencing adjuvant therapy (RR: 1.59, 95% CI 0.66 to 3.87, p = 0.30). Conclusion Immediate breast reconstruction after NACT is a safe procedure with an acceptable post-operative complication profile. It may result in a slight increase in implant loss rates, but it does not delay commencing adjuvant therapy

Neuro-Fuzzy Based High-Voltage DC Model to Optimize Frequency Stability of an Offshore Wind Farm

Lack of synchronization between high voltage DC systems linking offshore wind farms and the onshore grid is a natural consequence owing to the stochastic nature of wind energy. The poor synchronization results in increased system disturbances, grid contingencies, power loss, and frequency instability. Emphasizing frequency stability analysis, this research investigates a dynamic coordination control technique for a Double Fed Induction Generator (DFIG) consisting of OWFs integrated with a hybrid multi-terminal HVDC (MTDC) system. Line commutated converters (LCC) and voltage source converters (VSC) are used in the suggested control method in order to ensure frequency stability. The adaptive neuro-fuzzy inference approach is used to accurately predict wind speed in order to further improve frequency stability. The proposed HVDC system can integrate multiple distributed OWFs with the onshore grid system, and the control strategy is designed based on this concept. In order to ensure the transient stability of the HVDC system, the DFIG-based OWF is regulated by a rotor side controller (RSC) and a grid side controller (GSC) at the grid side using a STATCOM. The devised HVDC (MTDC) is simulated in MATLAB/SIMULINK, and the performance is evaluated in terms of different parameters, such as frequency, wind power, rotor and stator side current, torque, speed, and power. Experimental results are compared to a conventional optimal power flow (OPF) model to validate the performance.© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).fi=vertaisarvioitu|en=peerReviewed

Vulnerability analysis of satellite-based synchronized smart grids monitoring systems

The large-scale deployment of wide-area monitoring systems could play a strategic role in supporting the evolution of traditional power systems toward smarter and self-healing grids. The correct operation of these synchronized monitoring systems requires a common and accurate timing reference usually provided by a satellite-based global positioning system. Although these satellites signals provide timing accuracy that easily exceeds the needs of the power industry, they are extremely vulnerable to radio frequency interference. Consequently, a comprehensive analysis aimed at identifying their potential vulnerabilities is of paramount importance for correct and safe wide-area monitoring system operation. Armed with such a vision, this article presents and discusses the results of an experimental analysis aimed at characterizing the vulnerability of global positioning system based wide-area monitoring systems to external interferences. The article outlines the potential strategies that could be adopted to protect global positioning system receivers from external cyber-attacks and proposes decentralized defense strategies based on self-organizing sensor networks aimed at assuring correct time synchronization in the presence of external attacks

Latent tuberculosis among pregnant mothers in a resource poor setting in Northern Tanzania: a cross-sectional study

Untreated latent TB infection (LTBI) is a significant risk factor for active pulmonary tuberculosis, hence predisposing to adverse pregnancy outcomes and mother to child transmission. The prevalence of latent tuberculosis in pregnancy and its association, if any, with various socio-demographic, obstetric and clinical characteristics was evaluated. Northern Tanzania was chosen as the study site. In a cross-sectional study, a total of 286 pregnant women from 12 weeks gestational age to term were assessed. Screening was undertaken using an algorithm involving tuberculin skin testing, symptom screening in the form of a questionnaire, sputum testing for acid fast bacilli followed by shielded chest X-rays if indicated. HIV serology was also performed on consenting participants.\ud Prevalence of latent infection ranged between 26.2% and 37.4% while HIV sero prevalence was 4.5%. After multivariate logistic analysis it was found that age, parity, body mass index, gestational age, and HIV sero status did not have any significant association with tuberculin skin test results. However certain ethnic groups were found to be less vulnerable to LTBI as compared to others (Chi square = 10.55, p = 0.03). All sputum smears for acid fast bacilli were negative. The prevalence of latent tuberculosis in pregnant women was found to be relatively high compared to that of the general population. In endemic areas, socio-demographic parameters alone are rarely adequate in identifying women susceptible to TB infection; therefore targeted screening should be conducted for all pregnant women at high risk for activation (especially HIV positive women). As opposed to the current policy of passive case detection, there appears to be an imminent need to move towards active screening. Ethnicity may provide important clues into genetic and cultural differences which predispose to latent tuberculosis, and is worth exploring further