Anomalous isotopic predissociation in the F³Πu(v=1) state of O₂

Using a tunable, narrow-bandwidth vacuum-ultraviolet source based on third-harmonic generation from excimer-pumped dye-laser radiation, the F³Πu←X³Σg-(1,0)photoabsorption cross sections of ¹⁶O₂ and ¹⁸O₂ have been recorded in high resolution. Rotational analyses have been performed and the resultant F(v=1) term values fitted to the ³Π Hamiltonian of Brown and Merer [J. Mol. Spectrosc. 74, 488 (1979)]. A large rotationless isotope effect is observed in the F(v=1)predissociation, wherein the Lorentzian linewidth component for ¹⁸O₂ is a factor of ∼50 smaller than the corresponding ¹⁶O₂linewidth. This effect, a consequence of the nonadiabatic rotationless predissociation mechanism, is described using a coupled-channel treatment of the strongly Rydberg-valence-mixed 3Πu states. Significant J, e/f-parity, and sublevel dependencies observed in the isotopic F(v=1) rotational widths are found to derive from an indirect predissociation mechanism involving an accidental degeneracy with the E³Σ−u(v=3) level, itself strongly predissociated by ³Σ−u Rydberg-valence interactions, together with L-uncoupling (rotational) interactions between the Rydberg components of the F and E states. Transitions into the E(v=3) level are observed directly for the first time, specifically in the ¹⁸O₂ spectrumPartial support was provided by an NSF International Opportunities for Scientists and Engineers Program Grant No. INT-9513350, and Visiting Fellowships for G.S. and J.B.W. at the Australian National University

Unmasking quality: exploring meanings of health by doing art

This paper arises from a presentation at the ‘Quality in Healthcare’ symposium at Cumberland Lodge, England, in 2013. MK, CR and SH conceived the paper and led the writing of the manuscript. JF, JL-D, AC, DE contributed substantially to the intellectual content of the paper through providing critical commentary and interpretation. All authors read and approved the final manuscript

Deriving bases for Abelian functions

We present a new method to explicitly define Abelian functions associated with algebraic curves, for the purpose of finding bases for the relevant vector spaces of such functions. We demonstrate the procedure with the functions associated with a trigonal curve of genus four. The main motivation for the construction of such bases is that it allows systematic methods for the derivation of the addition formulae and differential equations satisfied by the functions. We present a new 3-term 2-variable addition formulae and a complete set of differential equations to generalise the classic Weierstrass identities for the case of the trigonal curve of genus four.Comment: 35page

Dynamics of gene expression and the regulatory inference problem

From the response to external stimuli to cell division and death, the dynamics of living cells is based on the expression of specific genes at specific times. The decision when to express a gene is implemented by the binding and unbinding of transcription factor molecules to regulatory DNA. Here, we construct stochastic models of gene expression dynamics and test them on experimental time-series data of messenger-RNA concentrations. The models are used to infer biophysical parameters of gene transcription, including the statistics of transcription factor-DNA binding and the target genes controlled by a given transcription factor.Comment: revised version to appear in Europhys. Lett., new titl

Re-evaluating the Relevance of Vegetation Trimlines in the Canadian Arctic as an Indicator of Little Ice Age Paleoenvironments

The origin of trimlines associated with the so-called “lichen-free” areas in the Canadian Arctic has been attributed both to perennial snowfield expansion during the Little Ice Age (LIA) and to seasonally persistent snow cover in more recent times. Because of the disparate hypotheses (ecological versus paleoclimatic) regarding the formation of these trimlines, their use as a paleoclimatic indicator has been abandoned for more than two decades. We re-examine this debate and the validity of the opposing hypotheses in the light of new regional mapping of trimlines across the Queen Elizabeth Islands (QEI). The ecological hypothesis—insufficient duration of the growing season resulting from seasonally persistent snow cover—fails to account for the poikilohydric nature of lichens and their ability to endure short growing seasons. It cannot adequately explain the existence of sharp trimlines or account for the occurrence of those trimlines on sparsely vegetated carbonate terrain. Furthermore, trimlines outlining the former extent of thin plateau ice caps are accordant with trimlines associated with former perennial snowfields, indicating that these trimlines record snow and ice expansion during the LIA rather than the seasonal persistence of more recent snow cover. We suggest that these features represent an important LIA climate indicator and should therefore be used for paleoclimatic reconstruction.L’origine des épaulements propres aux zones dites sans lichen de l’Arctique canadien a été attribuée tant à l’expansion des champs de neige pérenne pendant le petit âge glaciaire qu’à la couverture de neige longévive d’époques plus récentes. Puisqu’il existe des hypothèses disparates (écologiques par opposition à paléoclimatiques) quant à la formation de ces épaulements, on a arrêté de s’en servir à titre d’indicateur paléoclimatique depuis plus d’une vingtaine d’années. Ici, ce débat fait l’objet d’un nouvel examen où l’on se penche sur la validité des hypothèses divergentes à la lumière du nouveau mappage régional des épaulements des îles de la Reine-Élisabeth. L’hypothèse d’ordre écologique —durée insuffisante de la saison de croissance découlant de la couverture de neige longévive en saison —omet de tenir compte de la nature poecilitique du lichen et de son aptitude à endurer de courtes saisons de croissance. Cette hypothèse ne permet pas d’expliquer adéquatement l’existence d’épaulements précis ou de tenir compte de la présence de ces épaulements en terrain carbonaté à végétation éparse. Par ailleurs, les épaulements qui délimitent l’ancienne étendue des minces calottes glaciaires des plateaux correspondent aux épaulements associés aux anciens champs de neige pérenne, ce qui indique que ces épaulements dénotent les expansions de neige et de glace du petit âge glaciaire et non pas de la couverture de neige longévive saisonnière plus récente. On suggère que ces caractéristiques représentent un important indicateur climatique du petit âge glaciaire et par conséquent, qu’on devrait s’en servir à des fins de reconstruction paléoclimatique

Veterinary practitioners’ selection of diagnostic tests for the primary evaluation of colic in the horse

The aim of this study was to survey veterinary practitioners’ selection of diagnostic tests for horses with clinical signs of abdominal pain. A questionnaire was distributed to veterinary surgeons involved in the primary evaluation of horses with abdominal pain, including the respondent's demographics, selection of diagnostic tests and factors affecting decision-making. Data analysis included descriptive analysis, categorisation of free text and simple univariable correlations to explore the relationships between independent variables and the relative self-estimated frequency that diagnostic tests were performed. A total of 228 responses were analysed. Participants worked in mixed practice (55.7 per cent), first opinion equine (22.8 per cent), first and second opinion equine (17.9 per cent) and referral practice (3.1 per cent). The majority (48.2 per cent, 105/218) were very confident managing a colic case (confidence level 4/5). The most frequently used diagnostic tests were ‘response to analgesia’ (87.2±24.0 per cent cases), rectal examination (75.9±21.2 per cent) and nasogastric intubation (43.8±27.6 per cent). Approach varied between practitioners, and for all diagnostic tests with frequency of use ranging from 0 to 100 per cent of cases. ‘Risk to personal safety’ was the most common reason for not using rectal examination. Practitioner's opinion of their confidence level in managing a colic case was associated with how frequently they used different diagnostic tests. There was marked variation in practitioners’ approaches, highlighting the need for further evidence to support decision-making

Reviewing research evidence and the case of participation in sport and physical recreation by black and minority ethnic communities

The paper addresses the implications of using the process of systematic review in the many areas of leisure where there is a dearth of material that would be admitted into conventional Cochrane Reviews. This raises important questions about what constitutes legitimate knowledge, questions that are of critical import not just to leisure scholars, but to the formulation of policy. The search for certainty in an area that lacks conceptual consensus results in an epistemological imperialism that takes a geocentric form. While clearly, there is a need for good research design whatever the style of research, we contend that the wholesale rejection of insightful research is profligate and foolhardy. A mechanism has to be found to capitalise on good quality research of whatever form. In that search, we draw upon our experience of conducting a review of the material available on participation in sport and physical recreation by people from Black and minority ethnic groups. The paper concludes with a proposal for a more productive review process that makes better use of the full panoply of good quality research available. © 2012 © 2012 Taylor & Francis