195 research outputs found
Feedback: Still the Simplest and Best Solution
Most engineers are (indirectly) trained to be "feedforward thinkers" and they immediately think of "model inversion" when it comes to doing control. Thus, they prefer to rely on models instead of data, although feedback solutions in most cases are much simpler and more robust
Visual Summarization of Scholarly Videos using Word Embeddings and Keyphrase Extraction
Effective learning with audiovisual content depends on many factors. Besides
the quality of the learning resource's content, it is essential to discover the
most relevant and suitable video in order to support the learning process most
effectively. Video summarization techniques facilitate this goal by providing a
quick overview over the content. It is especially useful for longer recordings
such as conference presentations or lectures. In this paper, we present an
approach that generates a visual summary of video content based on semantic
word embeddings and keyphrase extraction. For this purpose, we exploit video
annotations that are automatically generated by speech recognition and video
OCR (optical character recognition).Comment: 12 pages, 5 figure
ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair
Background: The H69CIS200 and H69OX400 cell lines are novel models of low-level platinum-drug resistance. Resistance was not associated with increased cellular glutathione or decreased accumulation of platinum, rather the resistant cell lines have a cell cycle alteration allowing them to rapidly proliferate post drug treatment. Results: A decrease in ERCC1 protein expression and an increase in RAD51B foci activity was observed in association with the platinum induced cell cycle arrest but these changes did not correlate with resistance or altered DNA repair capacity. The H69 cells and resistant cell lines have a p53 mutation and consequently decrease expression of p21 in response to platinum drug treatment, promoting progression of the cell cycle instead of increasing p21 to maintain the arrest.
Conclusion: Decreased ERCC1 protein and increased RAD51B foci may in part be mediating the maintenance of the cell cycle arrest in the sensitive cells. Resistance in the H69CIS200 and H69OX400 cells may therefore involve the regulation of ERCC1 and RAD51B independent of their roles in DNA repair. The novel mechanism of platinum resistance in the H69CIS200 and H69OX400 cells demonstrates the multifactorial nature of platinum resistance which can occur independently of alterations in DNA repair capacity and changes in ERCC1
Temporal Analysis of Sentiment Events – A Visual Realization and Tracking
Abstract. In recent years, extraction of temporal relations for events that express sentiments has drawn great attention of the Natural Language Processing (NLP) research communities. In this work, we propose a method that involves the association and contribution of sentiments in determining the event-event relations from texts. Firstly, we employ a machine learning approach based on Conditional Random Field (CRF) for solving the problem of Task C (identification of event-event relations) of TempEval-2007 within TimeML framework by considering sentiment as a feature of an event. Incorporating sentiment property, our system achieves the performance that is better than all the participated state-of-the-art systems of TempEval 2007. Evaluation results on the Task C test set yield the F-score values of 57.2% under the strict evaluation scheme and 58.6 % under the relaxed evaluation scheme. The positive or negative coarse grained sentiments as well as the Ekman’s six basic universal emotions (or, fine grained sentiments) are assigned to the events. Thereafter, we analyze the temporal relations between events in order to track the sentiment events. Representation of the temporal relations in a graph format shows the shallow visual realization path for tracking the sentiments over events. Manual evaluation of temporal relations of sentiment events identified in 20 documents sounds satisfactory from the purview of event-sentiment tracking
Diagnostic accuracy of transabdominal ultrasound in chronic pancreatitis
The performance of transabdominal ultrasound (US) in chronic pancreatitis (CP) following the advances in US technology made during recent decades has not been explored. Our aim in this prospective study was to evaluate the diagnostic accuracy of modern abdominal US compared with the Mayo score in CP. One hundred thirty-four patients referred for suspected CP were included in the study. Fifty-four patients were assigned the diagnosis CP. After inclusion, transabdominal US was performed. Ductal features (calculi, dilations and caliber variations, side-branch dilations and hyper-echoic duct wall margins) and parenchymal features (calcifications, cysts, hyper-echoic foci, stranding, lobulation and honeycombing) were recorded. Features were counted and scored according to a weighting system defined at the international consensus meeting in Rosemont, Illinois (Rosemont score). Diagnostic performance indices (95% confidence interval) of US were calculated: The unweighted count of features had a sensitivity of 0.69 (0.54–0.80) and specificity of 0.97 (0.90–1). The Rosemont score had a sensitivity of 0.81 (0.69–0.91) and specificity of 0.97 (0.90–1). Exocrine pancreatic failure was most pronounced in Rosemont groups I and II (p < 0.001). We conclude that using both unweighted and weighted scores, the diagnostic accuracy of modern transabdominal US is good. The extent of pancreatic changes detected by the method is correlated with exocrine pancreatic function.publishedVersio
Professional Standards in Medical Ultrasound - EFSUMB Position Paper (Long Version) - General Aspects
This first position paper of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) on professional standards presents a common position across the different medical professions within EFSUMB regarding optimal standards for the performing and reporting of ultrasound examinations by any professional ultrasound operator. It describes general aspects of professionality that ensure procedure quality, effectiveness, efficiency, and sustainability in virtually all application fields of medical ultrasound. Recommendations are given related to safety and indication of ultrasound examinations, requirements for examination rooms, structured examination, systematic reporting of results, and management, communication and archiving of ultrasound data. The print version of this article is a short version. The long version is published online.publishersversionPeer reviewe
EFSUMB Guidelines on Interventional Ultrasound (INVUS), Part II : Diagnostic ultrasound-guided interventional procedures (Long Version)
Publisher Copyright: © Georg Thieme Verlag KG Stuttgart New York.This is the second part of the series on interventional ultrasound guidelines of the Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB). It deals with the diagnostic interventional procedure. General points are discussed which are pertinent to all patients, followed by organ-specific imaging that will allow the correct pathway and planning for the interventional procedure. This will allow for the appropriate imaging workup for each individual interventional procedure (Long version).publishersversionPeer reviewe
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