54 research outputs found
Quasinormal modes of massive charged flavor branes
We present an analysis and classification of vector and scalar fluctuations
in a D3/D7 brane setup at finite termperature and baryon density. The system is
dual to an N=2 supersymmetric Yang-Mills theory with SU(N_c) gauge group and
N_f hypermultiplets in the fundamental representation in the quenched
approximation. We improve significantly over previous results on the
quasinormal mode spectrum of D7 branes and stress their novel physical
interpretation. Amongst our findings is a new purely imaginary scalar mode that
becomes tachyonic at sufficiently low temperature and baryon density. We
establish the existence of a critical density above which the scalar mode stays
in the stable regime for all temperatures. In the vector sector we study the
crossover from the hydrodynamic to the quasiparticle regime and find that it
moves to shorter wavelengths for lower temperatures. At zero baryon density the
quasinormal modes move toward distinct discrete attractor frequencies that
depend on the momentum as we increase the temperature. At finite baryon
density, however, the trajectories show a turning behavior such that for low
temperature the quasinormal mode spectrum approaches the spectrum of the
supersymmetric zero temperature normal modes. We interpret this as resolution
of the singular quasinormal mode spectrum that appears at the limiting D7 brane
embedding at vanishing baryon density.Comment: 56 pages, 40 figure
Persistent DNA Damage after High Dose In Vivo Gamma Exposure of Minipig Skin
Exposure to high doses of ionizing radiation (IR) can lead to localized radiation injury of the skin and exposed cells suffer dsDNA breaks that may elicit cell death or stochastic changes. Little is known about the DNA damage response after high-dose exposure of the skin. Here, we investigate the cellular and DNA damage response in acutely irradiated minipig skin.IR-induced DNA damage, repair and cellular survival were studied in 15 cm(2) of minipig skin exposed in vivo to ~50 Co-60 γ rays. Skin biopsies of control and 4 h up to 96 days post exposure were investigated for radiation-induced foci (RIF) formation using γ-H2AX, 53BP1, and active ATM-p immunofluorescence. High-dose IR induced massive γ-H2AX phosphorylation and high 53BP1 RIF numbers 4 h, 20 h after IR. As time progressed RIF numbers dropped to a low of <1% of keratinocytes at 28-70 days. The latter contained large RIFs that included ATM-p, indicating the accumulation of complex DNA damage. At 96 days most of the cells with RIFs had disappeared. The frequency of active-caspase-3-positive apoptotic cells was 17-fold increased 3 days after IR and remained >3-fold elevated at all subsequent time points. Replicating basal cells (Ki67+) were reduced 3 days post IR followed by increased proliferation and recovery of epidermal cellularity after 28 days.Acute high dose irradiation of minipig epidermis impaired stem cell replication and induced elevated apoptosis from 3 days onward. DNA repair cleared the high numbers of DBSs in skin cells, while RIFs that persisted in <1% cells marked complex and potentially lethal DNA damage up to several weeks after exposure. An elevated frequency of keratinocytes with persistent RIFs may thus serve as indicator of previous acute radiation exposure, which may be useful in the follow up of nuclear or radiological accident scenarios
No-destructive testing of particleborad properties—with special respect to the modulus of elasticity (MOE) for bending
Dependences of the Fastest Growing Williams Mode on an Applied Field in Electrohydrodynamics
Simulation of cell survival for proton broad and minibeam radiotherapy with hexagonal and square minibeam alignment
191 Simulation of cell survival for proton broad and minibeam radiotherapy with hexagonal and square minibeam alignment
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