49 research outputs found
Inheritance of some morphological characters in chickpea (Cicer arietinum L.)
The present investigation was undertaken to generate information on the inheritance of flower colour, leaflet size and pigmented stem in chickpea (Cicer arietinum L.). Parents, F1’s, and F2’s of crosses Vijay x PKV-4, Digvijay x PKV-4 and BDNG-797 x PKV-4 were evaluated during rabi, 2018-19. The monogenic inheritance was confirmed for two traits, pink vs. white flower colour and pigmented vs. non pigmented stem pigmentation. Leaflet size, small vs. broad was controlled by duplicate gene action. The genetic inheritance of these morphological traits is essential for the selection of superior and desirable transgressive segregants for the genetic improvement of the crop. These results are of essential significance because these traits are used as visual markers in chickpea breeding for early recognition of the hybrid nature of plants
Evaluation of Critical Quality Attributes of a Pentavalent (A, C, Y, W, X) Meningococcal Conjugate Vaccine for Global Use
Towards achieving the goal of eliminating epidemic outbreaks of meningococcal disease in the African meningitis belt, a pentavalent glycoconjugate vaccine (NmCV-5) has been developed to protect against Neisseria meningitidis serogroups A, C, Y, W and X. MenA and X polysaccharides are conjugated to tetanus toxoid (TT) while MenC, Y and W polysaccharides are conjugated to recombinant cross reactive material 197 (rCRM197), a non-toxic genetic variant of diphtheria toxin. This study describes quality control testing performed by the manufacturer, Serum Institute of India Private Limited (SIIPL), and the independent control laboratory of the U.K. (NIBSC) on seven clinical lots of the vaccine to ensure its potency, purity, safety and consistency of its manufacturing. In addition to monitoring upstream-manufactured components, samples of drug substance, final drug product and stability samples were evaluated. This paper focuses on the comparison of the vaccine’s critical quality attributes and reviews key indicators of its stability and immunogenicity. Comparable results were obtained by the two laboratories demonstrating sufficient levels of polysaccharide O-acetylation, consistency in size of the bulk conjugate molecules, integrity of the conjugated saccharides in the drug substance and drug product, and acceptable endotoxin content in the final drug product. The freeze-dried vaccine in 5-dose vials was stable based on molecular sizing and free saccharide assays. Lot-to-lot manufacturing consistency was also demonstrated in preclinical studies for polysaccharide-specific IgG and complement-dependent serum bactericidal activity for each serogroup. This study demonstrates the high quality and stability of NmCV-5, which is now undergoing Phase 3 clinical trials in Africa and India
MULTISPECTRAL SUPER RESOLUTION AND IMAGE QUALITY ASSESSMENT COMPARATIVE ANALYSIS
The satellite image resolution alludes to highest accuracy to capture finer details from scene. This paper addresses five different techniques to improve resolution of multispectral satellite image. Our algorithm generates super resolved multispectral image using advantages of Patch Based processing. The results are then compared with four techniques Bicubic Interpolation, Edge Directed Orientation, Patch Based Processing, Gaussian Process Regression (GPR). Comparative analysis is carried out with reference to Mean Square Error (MSE), Peak Signal to Noise Ratio (PSNR), Image Fidelity, correlation coefficient and similarity measure, processing speed and storage space required. Image quality assessments (IQA) parameters are also performed. Super resolution (SR) is commercial algorithm to improve resolution of satellite image when we compare with image fusion
Multispectral Super Resolution and Image Quality Assessment Comparative Analysis
The satellite image resolution alludes to highest accuracy to capture finer details from scene. This paper addresses five different techniques to improve resolution of multispectral satellite image. Our algorithm generates super resolved multispectral image using advantages of Patch Based processing. The results are then compared with four techniques Bicubic Interpolation, Edge Directed Orientation, Patch Based Processing, Gaussian Process Regression (GPR). Comparative analysis is carried out with reference to Mean Square Error (MSE), Peak Signal to Noise Ratio (PSNR), Image Fidelity, correlation coefficient and similarity measure, processing speed and storage space required. Image quality assessments (IQA) parameters are also performed. Super resolution (SR) is commercial algorithm to improve resolution of satellite image when we compare with image fusion
Ocean Surface Trash Collector
This paper describes the design of a robot for collecting waste floating on the water surface. Three important issues for designing the aquatic robots are a cost-effective solution along with robustness and durability. Due to the nature of the cleaning work, we designed the robot structure with car like mechanism that can provide high stability, good ability in maneuver and can easily collect all the waste flowing on the water. The plastic pipe container works best for this case and fulfils all structural stability criteria. For collection of waste, a motor-driven conveyor belt has been designed for collecting the wastes and deploy it into a plastic box connected to the platform. This design provides simple and effective waste removal and accommodates large amounts of waste within a little space. This light-weight and tough structure support the total weight of the collected waste, conveyor as well as the hardware components used. The rotating arms system based a differential drive mechanism has been designed, which allows the robots to require a 360 turn on the spot and provides high thrust. Electronic circuit and motors have been placed on the platform, in order to protect them from water. The robot is automatically controlled by Arduino, sensors, motor driver, GPS and GSM modules. The testing of the robot prototype proved to be effective in waste collecting and getting back to the way-point. The maximum trash loads that robot can bear is up 5 kg. The main aim of the project is to optimize time, energy and overall process speed
PNEUMATIC EQUIPMENTIN MASS PRODUCTON SYSTEMFOR GRINDING
Nowadays every one focus on various pneumatic application in industrial areas because due to the continuous availability of compressed air in industry. It is possible to drive the number of applications using pneumatic circuit. So, we are also choosingthe same way of study for improvement of plant efficiency. Our main objective is Experimental study on Pneumatic Grinding Machine. This study gives the better result of surface finishing of various material applications