A Supersymmetric SpL×UY(1)Sp_{L} \times U_{Y}(1) Model

A supersymmetric $Sp_{L}(6) \times U_{Y}(1)$ model (SUSY $Sp(6)$) is proposed as an extension of the standard electroweak model. The model is applied in a phenomenological study of $B^{0}_{d} \bar{B}^{0}_{d}$ mixing. It is found that the supersymmetric (SUSY) partner $\tilde{z}^{\prime}$ of the extra $Z^{\prime}$ can significantly cancel the other contributions to bring the mixing parameter $x_{d}$ within the experimentally allowed range $0.57 \stackrel{<}{\sim} x_{d} \stackrel{<}{\sim} 0.77$ for a top mass of $158 \stackrel{<}{\sim} m_{t} \stackrel{<}{\sim} 194$ Gev. Other interesting and possibly novel features of flavor changing neutral currents (FCNC) in SUSY theories with horizontal gauge symmetries are pointed out.Comment: to be published at the Il Nuovo Cimento A; uses FEYNMAN.tex; hard copy available from G. G. Blado ([email protected]) by regular mail upon e-mail request

The Mayer-Rokitansky-Küster-Hauser syndrome (congenital absence of uterus and vagina) – phenotypic manifestations and genetic approaches

The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome affects at least 1 out of 4500 women and has for a long time been considered as a sporadic anomaly. Congenital absence of upper vagina and uterus is the prime feature of the disease which, in addition, is often found associated with unilateral renal agenesis or adysplasia as well as skeletal malformations (MURCS association). The phenotypic manifestations of MRKH overlap various other syndromes or associations and thus require accurate delineation. Since MRKH manifests itself in males, the term GRES syndrome (Genital, Renal, Ear, Skeletal) might be more appropriate when applied to both sexes. The MRKH syndrome, when described in familial aggregates, seems to be transmitted as an autosomal dominant trait with an incomplete degree of penetrance and variable expressivity. This suggests the involvement of either mutations in a major developmental gene or a limited chromosomal deletion. Until recently progress in understanding the genetics of MRKH syndrome has been slow, however, now HOX genes have been shown to play key roles in body patterning and organogenesis, and in particular during genital tract development. Expression and/or function defects of one or several HOX genes may account for this syndrome

Innovative ways to improve patient family knowledge of inpatient safety

Empowering consumers and families in a hospital safety agenda, through education, has been shown to improve a culture of hospital safety. Engagement of paediatric consumers and their family in patient safety is a complex problem and requires a multifaceted approach. The development of educational resources that are family centred, culturally sensitive and targeted is a fundamental step towards improving paediatric patient safety and central to family centred care. Our previous patient safety quality improvement & research identified that some existing paediatric patient safety resources did not meet the educational needs of all paediatric patients and their family (Ritz-Shala et al, 2019). In particular, paediatric consumers preferred information technology and social media. A multi-disciplinary team of SCHN healthcare professionals formed a working party to develop an inpatient safety video. The short-animated video uses simplified imagery and narration to educate paediatric patients and their families about eight key inpatient safety issues such as the prevention of pressure injuries, medication related errors, inpatient falls, and how concerned parents can activate a rapid response and/or clinical review in the event that their child’s health is deteriorating. Several draft videos were critically reviewed for the acceptability of animated pictures, educational content, simplicity of narrated dialogue, cultural sensitivity and developmental appropriateness. Meetings were held in COVID safe environment. The patient safety video will be reviewed and endorsed by the SCHN Families and Consumer Council in December 2020. The final version of the patient safety video will be edited and published internally early-mid 2021 on the SCHN OneView system. One-view systems are available at each inpatient bed and allows access to entertainment and health information via an iPad. Children, parents and carers are able to access this information system at the bedside while in hospital. An evaluation plan has been developed and outcomes will be presented

Virus erpetici come vettori vaccinali

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