2,352 research outputs found
Neutron Drops and Skyrme Energy-Density Functionals
The J=0 ground state of a drop of 8 neutrons and the lowest
1/2 and 3/2 states of 7-neutron drops, all in an external well, are
computed accurately with variational and Green's function Monte Carlo methods
for a Hamiltonian containing the Argonne two-nucleon and Urbana IX
three-nucleon potentials. These states are also calculated using Skyrme-type
energy-density functionals. Commonly used functionals overestimate the central
density of these drops and the spin-orbit splitting of 7-neutron drops.
Improvements in the functionals are suggested
Quantum Monte Carlo calculations of spectroscopic overlaps in nuclei
We present Green's function Monte Carlo calculations of spectroscopic
overlaps for nuclei. The realistic Argonne v18 two-nucleon and
Illinois-7 three-nucleon interactions are used to generate the nuclear states.
The overlap matrix elements are extrapolated from mixed estimates between
variational Monte Carlo and Green's function Monte Carlo wave functions. The
overlap functions are used to obtain spectroscopic factors and asymptotic
normalization coefficients, and they can serve as an input for low-energy
reaction calculations
Ground state correlations and mean-field in O
We use the coupled cluster expansion ( method) to generate the
complete ground state correlations due to the NN interaction. Part of this
procedure is the calculation of the two-body G matrix inside the nucleus in
which it is being used. This formalism is being applied to in a
configuration space of 50 . The resulting ground state wave
function is used to calculate the binding energy and one- and two-body
densities for the ground state of .Comment: 9 pages, 9 figures, LaTe
Local three-nucleon interaction from chiral effective field theory
The three-nucleon (NNN) interaction derived within the chiral effective field
theory at the next-to-next-to-leading order (N2LO) is regulated with a function
depending on the magnitude of the momentum transfer. The regulated NNN
interaction is then local in the coordinate space, which is advantages for some
many-body techniques. Matrix elements of the local chiral NNN interaction are
evaluated in a three-nucleon basis. Using the ab initio no-core shell model
(NCSM) the NNN matrix elements are employed in 3H and 4He bound-state
calculations.Comment: 17 pages, 9 figure
Neuroprotective efficacy of P7C3 compounds in primate hippocampus.
There is a critical need for translating basic science discoveries into new therapeutics for patients suffering from difficult to treat neuropsychiatric and neurodegenerative conditions. Previously, a target-agnostic in vivo screen in mice identified P7C3 aminopropyl carbazole as capable of enhancing the net magnitude of postnatal neurogenesis by protecting young neurons from death. Subsequently, neuroprotective efficacy of P7C3 compounds in a broad spectrum of preclinical rodent models has also been observed. An important next step in translating this work to patients is to determine whether P7C3 compounds exhibit similar efficacy in primates. Adult male rhesus monkeys received daily oral P7C3-A20 or vehicle for 38 weeks. During weeks 2-11, monkeys received weekly injection of 5'-bromo-2-deoxyuridine (BrdU) to label newborn cells, the majority of which would normally die over the following 27 weeks. BrdU+ cells were quantified using unbiased stereology. Separately in mice, the proneurogenic efficacy of P7C3-A20 was compared to that of NSI-189, a proneurogenic drug currently in clinical trials for patients with major depression. Orally-administered P7C3-A20 provided sustained plasma exposure, was well-tolerated, and elevated the survival of hippocampal BrdU+ cells in nonhuman primates without adverse central or peripheral tissue effects. In mice, NSI-189 was shown to be pro-proliferative, and P7C3-A20 elevated the net magnitude of hippocampal neurogenesis to a greater degree than NSI-189 through its distinct mechanism of promoting neuronal survival. This pilot study provides evidence that P7C3-A20 safely protects neurons in nonhuman primates, suggesting that the neuroprotective efficacy of P7C3 compounds is likely to translate to humans as well
Structure of boson systems beyond the mean-field
We investigate systems of identical bosons with the focus on two-body
correlations. We use the hyperspherical adiabatic method and a decomposition of
the wave function in two-body amplitudes. An analytic parametrization is used
for the adiabatic effective radial potential. We discuss the structure of a
condensate for arbitrary scattering length. Stability and time scales for
various decay processes are estimated. The previously predicted Efimov-like
states are found to be very narrow. We discuss the validity conditions and
formal connections between the zero- and finite-range mean-field
approximations, Faddeev-Yakubovskii formulation, Jastrow ansatz, and the
present method. We compare numerical results from present work with mean-field
calculations and discuss qualitatively the connection with measurements.Comment: 26 pages, 6 figures, submitted to J. Phys. B. Ver. 2 is 28 pages with
modified figures and discussion
Spin susceptibility of neutron matter at zero temperature
The Auxiliary Field Diffusion Monte Carlo method is applied to compute the
spin susceptibility and the compressibility of neutron matter at zero
temperature. Results are given for realistic interactions which include both a
two-body potential of the Argonne type and the Urbana IX three-body potential.
Simulations have been carried out for about 60 neutrons. We find an overall
reduction of the spin susceptibilty by about a factor 3 with respect to the
Pauli susceptibility for a wide range of densities. Results for the
compressibility of neutron matter are also presented and compared with other
available estimates obtained for semirealistic nucleon-nucleon interactions by
using other techniques
- …