52,781 research outputs found
On the Dichotomy between the Nodal and Antinodal Excitations in High-temperature Superconductors
Angle-resolved photoemission data on optimally- and under-doped high
temperature superconductors reveal a dichotomy between the nodal and antinodal
electronic excitations. In this paper we propose an explanation of this unusual
phenomenon by employing the coupling between the quasiparticle and the
commensurate/incommensurate magnetic excitations.Comment: 11 pages, 9 figure
3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival
Copyright © 2011 Association for Research in Vision and Ophthalmology. This article is available open access through the publisher’s website at the link below.Purpose. IDO (indoleamine 2,3-dioxygenase) modulates the immune response by depletion of the essential amino acid tryptophan, and IDO overexpression has been shown to prolong corneal allograft survival. This study was conducted to examine the effect of kynurenines, the products of tryptophan breakdown and known to act directly on T lymphocytes, on corneal graft survival.
Methods. The effects of kynurenines on T-cell proliferation and death, T-regulatory-cell development, and dendritic cell function, phenotype, and viability were analyzed in vitro. The effect of topical and systemic administration of 3-hydroxykynurenine (3HK) on orthotopic murine corneal allograft survival was examined.
Results. T-lymphocyte proliferation was inhibited by two of the four different kynurenines: 3HK and 3-hydroxyanthranilic acid (3HAA). This effect was accompanied by significant T-cell death. Neither 3HK nor 3HAA altered dendritic cell function, nor did they induce apoptosis or pathogenicity to corneal endothelial cells. Administration of systemic and topical 3HK to mice receiving a fully mismatched corneal graft resulted in significant prolongation of graft survival (median survival of control grafts, 12 days; of treated, 19 and 15 days, respectively; P < 0.0003). While systemic administration of 3HK was associated with a significant depletion of CD4+ T, CD8+ T, and B lymphocytes in peripheral blood, no depletion was found after topical administration.
Conclusions. The production of kynurenines, in particular 3HK and 3HAA, may be one mechanism (in addition to tryptophan depletion) by which IDO prolongs graft survival. These molecules have potential as specific agents for preventing allograft rejection in patients at high rejection risk.Fight for Sight and the Wellcome Trust
Nonlinearity-assisted quantum tunneling in a matter-wave interferometer
We investigate the {\em nonlinearity-assisted quantum tunneling} and
formation of nonlinear collective excitations in a matter-wave interferometer,
which is realised by the adiabatic transformation of a double-well potential
into a single-well harmonic trap. In contrast to the linear quantum tunneling
induced by the crossing (or avoided crossing) of neighbouring energy levels,
the quantum tunneling between different nonlinear eigenstates is assisted by
the nonlinear mean-field interaction. When the barrier between the wells
decreases, the mean-field interaction aids quantum tunneling between the ground
and excited nonlinear eigenstates. The resulting {\em non-adiabatic evolution}
depends on the input states. The tunneling process leads to the generation of
dark solitons, and the number of the generated dark solitons is highly
sensitive to the matter-wave nonlinearity. The results of the numerical
simulations of the matter-wave dynamics are successfully interpreted with a
coupled-mode theory for multiple nonlinear eigenstates.Comment: 11 pages, 6 figures, accept for publication in J. Phys.
Phase-diagram of two-color lattice QCD in the chiral limit
We study thermodynamics of strongly coupled lattice QCD with two colors of
massless staggered fermions as a function of the baryon chemical potential
in 3+1 dimensions using a new cluster algorithm. We find evidence that
the model undergoes a weak first order phase transition at which
becomes second order at a finite . Symmetry considerations suggest that
the universality class of these phase transitions should be governed by an
field theory with collinear order, with N=3 at and
N=2 at . The universality class of the second order phase
transition at appears to be governed by the decoupled XY fixed
point present in the field theory. Finally we show that the
quantum (T=0) phase transition as a function of is a second order mean
field transition.Comment: 31 pages, 12 figure
Ab-initio GMR and current-induced torques in Au/Cr multilayers
We report on an {\em ab-initio} study of giant magnetoresistance (GMR) and
current-induced-torques (CITs) in Cr/Au multilayers that is based on
non-equilibrium Green's functions and spin density functional theory. We find
substantial GMR due primarily to a spin-dependent resonance centered at the
Cr/Au interface and predict that the CITs are strong enough to switch the
antiferromagnetic order parameter at current-densities times smaller
than typical ferromagnetic metal circuit switching densities.Comment: 8 pages, 6 figure
Electrical spin protection and manipulation via gate-locked spin-orbit fields
The spin-orbit (SO) interaction couples electron spin and momentum via a
relativistic, effective magnetic field. While conveniently facilitating
coherent spin manipulation in semiconductors, the SO interaction also
inherently causes spin relaxation. A unique situation arises when the Rashba
and Dresselhaus SO fields are matched, strongly protecting spins from
relaxation, as recently demonstrated. Quantum computation and spintronics
devices such as the paradigmatic spin transistor could vastly benefit if such
spin protection could be expanded from a single point into a broad range
accessible with in-situ gate-control, making possible tunable SO rotations
under protection from relaxation. Here, we demonstrate broad, independent
control of all relevant SO fields in GaAs quantum wells, allowing us to tune
the Rashba and Dresselhaus SO fields while keeping both locked to each other
using gate voltages. Thus, we can electrically control and simultaneously
protect the spin. Our experiments employ quantum interference corrections to
electrical conductivity as a sensitive probe of SO coupling. Finally, we
combine transport data with numerical SO simulations to precisely quantify all
SO terms.Comment: 5 pages, 4 figures (color), plus supplementary information 18 pages,
8 figures (color) as ancillary arXiv pd
Entanglement and quantum phase transition in the one-dimensional anisotropic XY model
In this paper the entanglement and quantum phase transition of the
anisotropic s=1/2 XY model are studied by using the quantum renormalization
group method. By solving the renormalization equations, we get the trivial
fixed point and the untrivial fixed point which correspond to the phase of the
system and the critical point, respectively. Then the concurrence between two
blocks are calculated and it is found that when the number of the iterations of
the renormalziation trends infinity, the concurrence develops two staturated
values which are associated with two different phases, i.e., Ising-like and
spin-fluid phases. We also investigate the first derivative of the concurrence,
and find that there exists non-analytic behaviors at the quantum critical
point, which directly associate with the divergence of the correlation length.
Further insight, the scaling behaviors of the system are analyzed, it is shown
that how the maximum value of the first derivative of the concurrence reaches
the infinity and how the critical point is touched as the size of the system
becomes large.Comment: 10 pages, 5 figure
Introducing the Dark Energy Universe Simulation Series (DEUSS)
In this "Invisible Universe" proceedings, we introduce the Dark Energy
Universe Simulation Series (DEUSS) which aim at investigating the imprints of
realistic dark energy models on cosmic structure formation. It represents the
largest dynamical dark energy simulation suite to date in term of spatial
dynamics. We first present the 3 realistic dark energy models (calibrated on
latest SNIa and CMB data): LambdaCDM, quintessence with Ratra-Peebles
potential, and quintessence with Sugra potential. We then isolate various
contributions for non-linear matter power spectra from a series of pre-DEUSS
high-resolution simulations (130 million particles). Finally, we introduce
DEUSS which consist in 9 Grand Challenge runs with 1 billion particles each
thus probing scales from 4 Gpc down to 3 kpc at z=0. Our goal is to make these
simulations available to the community through the "Dark Energy Universe
Virtual Observatory" (DEUVO), and the "Dark Energy Universe Simulations" (DEUS)
consortium.Comment: 6 pages, 3 figures, to appear in the AIP proceedings of the
'Invisible Universe International Conference', UNESCO-Paris, June 29-July 3,
200
Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) PARM tape user's guide
The Scanning Multichannel Microwave Radiometer (SMMR) instrument, onboard the Nimbus-7 spacecraft, collected data from Oct. 1978 until Jun. 1986. The data were processed to physical parameter level products. Geophysical parameters retrieved include the following: sea-surface temperatures, sea-surface windspeed, total column water vapor, and sea-ice parameters. These products are stored on PARM-LO, PARM-SS, and PARM-30 tapes. The geophysical parameter retrieval algorithms and the quality of these products are described for the period between Nov. 1978 and Oct 1985. Additionally, data formats and data availability are included
A massive, distant proto-cluster at z=2.47 caught in a phase of rapid formation?
Numerical simulations of cosmological structure formation show that the
Universe's most massive clusters, and the galaxies living in those clusters,
assemble rapidly at early times (2.5 < z < 4). While more than twenty
proto-clusters have been observed at z > 2 based on associations of 5-40
galaxies around rare sources, the observational evidence for rapid cluster
formation is weak. Here we report observations of an asymmetric, filamentary
structure at z = 2.47 containing seven starbursting, submillimeter-luminous
galaxies and five additional AGN within a comoving volume of 15000 Mpc.
As the expected lifetime of both the luminous AGN and starburst phase of a
galaxy is ~100 Myr, we conclude that these sources were likely triggered in
rapid succession by environmental factors, or, alternatively, the duration of
these cosmologically rare phenomena is much longer than prior direct
measurements suggest. The stellar mass already built up in the structure is
and we estimate that the cluster mass will exceed that
of the Coma supercluster at . The filamentary structure is in line
with hierarchical growth simulations which predict that the peak of cluster
activity occurs rapidly at z > 2.Comment: 7 pages, 3 figures, 2 tables, accepted in ApJL (small revisions from
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