Novel thiophene symmetrical Schiff base compounds as corrosion inhibitor for mild steel in acidic media

The inhibiting effect of two Schiff bases on the corrosion of the mild steel (MS) in 1 M HCl has been studied by electrochemical impedance spectroscopy (EIS) and Tafel polarisation measurements. The Schiff bases, 4,4′-bis(3-carboxaldehyde thiophene) diphenyl diimino ether (L1) and 4,4′-bis(3-carboxaldehyde thiophene) diphenyl diimino ethane (L2), were synthesized using 3-carboxaldehydethiophene and its corresponding amine. Polarisation curves reveal that both compounds are mixed type (cathodic/anodic) inhibitors and inhibition efficiency (% IE) increases with increasing concentration of compounds. It is suggested that their effects depend on their concentrations and the molecular structures. Adsorption of compounds on mild steel surface is spontaneous and obeys Langmuir’s isotherm

Production and partial characterization of chitinase from a halotolerant Planococcus rifitoensis strain M2-26

peer reviewedThis paper is the first to investigate the production and partial characterization of the chitinase enzyme from a moderately halophilic bacterium Planococcus rifitoensis strain M2-26, earlier isolated from a shallow salt lake in Tunisia. The impact of salt, salinity concentration, pH, carbon and nitrogen sources on chitinase production and activity have been determined. This is the first report on a high salt-tolerant chitinase from P. rifitoensis, since it was active at high salinity (from 5 to 30% NaCl) as well as in the absence of salt. This enzyme showed optimal activity at 70 C and retained up to 82 and 66% of its original activity at 80 or 90 C, respectively. The activity of the enzyme was also shown over a wide pH range (from 5 to 11). For characterization of the enzyme activity, the chitinase secreted in the culture supernatant was partially purified. The preliminary study of the concentrated dialysed supernatant on native PAGE showed at least three chitinases produced by strain M2-26, with highest activity approximately at 65 kDa. Thus, the thermo-tolerant and high salt-tolerant chitinases produced by P. rifitoensis strain M2-26 could be useful for application in diverse areas such as biotechnology and agro-industry

Métastases choroïdiennes bilatérales révélatrices d’un cancer bronchopulmonaire chez une femme enceinte

Les métastases choroïdiennes révélatrices d’un cancer primitif sont rares, elles surviennent généralement chez des patients qui ont un cancer connu et traité. Les tumeurs primitives les plus souvent à l’origine des métastases choroïdiennes sont le cancer du poumon chez l’homme et le carcinome du sein chez la femme.Nous rapportons le cas d’un cancer non à petite cellules du poumon révélé par des métastases choroïdiennes bilatérales, chez une femme de 29 ans, enceinte de 20 semaines qui consulte à notre service pour cécité bilatérale.L’examen ophtalmologique a retrouvé une acuité visuelle réduite à voir bouger la main à droite et 02/100 à gauche. L’examen du segment antérieur des deux yeux était normal. Le fond d’œil des deux yeux a retrouvé une lésion choroïdienne postérieure surélevée surmontée d’un important décollement de rétine exsudatif. L’échographie en mode B a retrouvé une masse en dôme échogène surmontée d’un décollement de rétine aux deux yeux. L’IRM orbito-cérébrale a confirmé la présence d’une masse choroïdienne aux deux yeux ainsi que des localisations secondaires cérébrales. Une IRM thoraco-abdomino-pelvienne à la recherche d’une tumeur primitive a retrouvé un processus tumoral du hile pulmonaire ainsi que des localisations secondaires hépatique et rénal de même qu’une formation sous cutanée lombaire dont la biopsie a révélé, une localisation cutanée secondaire d’un adénocarcinome non à petites cellules (NOS) du poumon. Le traitement a consisté en une chimiothérapie palliative

Temporal Dissociation between Myeloperoxidase (MPO)-Modified LDL and MPO Elevations during Chronic Sleep Restriction and Recovery in Healthy Young Men

OBJECTIVES: Many studies have evaluated the ways in which sleep disturbances may influence inflammation and the possible links of this effect to cardiovascular risk. Our objective was to investigate the effects of chronic sleep restriction and recovery on several blood cardiovascular biomarkers. METHODS AND RESULTS: Nine healthy male non-smokers, aged 22-29 years, were admitted to the Sleep Laboratory for 11 days and nights under continuous electroencephalogram polysomnography. The study consisted of three baseline nights of 8 hours sleep (from 11 pm to 7 am), five sleep-restricted nights, during which sleep was allowed only between 1 am and 6 am, and three recovery nights of 8 hours sleep (11 pm to 7 am). Myeloperoxidase-modified low-density lipoprotein levels increased during the sleep-restricted period indicating an oxidative stress. A significant increase in the quantity of slow-wave sleep was measured during the first recovery night. After this first recovery night, insulin-like growth factor-1 levels increased and myeloperoxidase concentration peaked. CONCLUSIONS: We observed for the first time that sleep restriction and the recovery process are associated with differential changes in blood biomarkers of cardiovascular disease