Alien Registration- Wibberley, Jennie S. (Millinocket, Penobscot County)

https://digitalmaine.com/alien_docs/7059/thumbnail.jp

Sensitivity analysis of a model for direct reduction in swelling coal char-hematite composite pellets

This paper describes a study of the optimisation of the modelling of the direct reduction process in swelling coal char-hematite composite pellets. Approximations of important physical parameters such as heats of reaction, specific heat and thermal conductivity of the reducing mixture have been developed. Without introducing significant errors, the computation time can be halved. The effect of the determination of pellet size and of the activation energies of the reducing reactions on the modelling results has also been investigated

Disclosure decisions within transition narratives: How ex-drug users decide what information to share when working toward employment in the substance misuse field

Ex-user narratives often “end” at the point where treatment ends, leaving much to discover regarding what happens next. Within this post-treatment experience, ex-users making the transition to work in the drugs field must decide whether or not to disclose their past substance use and, if they do disclose, further personal decision-making relates to how much to disclose, to whom, and in what context. This article explores ex-drug users’ decisions around disclose of their background to colleagues and service users. In-depth narrative interviews were undertaken with 11 ex-drug users to explore their journey to become substance misuse practitioners and their decisions around disclosure within this transition. Process mapping was used to enable participants to structure their story in their own way. Following thematic analysis, it became apparent that most participants received little or no guidance regarding disclosure. In the absence of clear guidelines regarding personal disclosures,reflective practice could be seen as a potential tool to enable participants to assess such risks and rewards. Alongside personal reflexivity, consideration should be given by service providers to disclosure policies, induction and ongoing training, and supervision in order to support ex-user drug workers’ disclosure decision-making

Effects of the Fluoroquinolones Moxifloxacin and Levofloxacin on the QT Subintervals: Sex Differences in Ventricular Repolarization.

Women are associated with longer electrocardiographic QT intervals and increased proarrhythmic risks of QT-prolonging drugs. The purpose of this study was to characterize the differences in cardiac electrophysiology between moxifloxacin and levofloxacin in men and women and to assess the balance of inward and outward currents through the analysis of QT subintervals. Data from 2 TQT studies were used to investigate the impact of moxifloxacin (400 mg) and levofloxacin (1000 and 1500 mg) on QT subintervals using algorithms for measurement of J-Tpeak and Tpeak -Tend intervals. Concentration-effect analyses were performed to establish potential relationships between the ECG effects and the concentrations of the 2 fluoroquinolones. Moxifloxacin was shown to be a more potent prolonger of QT interval corrected by Fredericia (QTcF) and had a pronounced effect on J-Tpeak c. Levofloxacin had little effect on J-Tpeak c. For moxifloxacin, the concentration-effect modeling showed a greater effect for women on QTcF and J-Tpeak c, whereas for levofloxacin the inverse was true: women had smaller QTcF and J-Tpeak c effects. The different patterns in repolarization after administration of both drugs suggested a sex difference, which may be related to the combined IKs and IKr inhibitory properties of moxifloxacin versus IKr suppression only of levofloxacin. The equipotent inhibition of IKs and IKr appears to affect women more than men. Sex hormones are known to influence cardiac ion channel expression and differences in QT duration. Differences in IKr and IKs balances, influenced by sex hormones, may explain the results. These results support the impact of sex differences on the cardiac safety assessment of drugs

A portable and affordable extensional rheometer for field testing

Extensional shear testing is often needed to characterise the behaviour of complex fluids found in industry and nature. Traditional extensional rheometers are typically expensive, fragile and heavy and are only suited to making measurements in a laboratory environment. For some applications, it is necessary to make in situ rheological measurements where, for example, fluid properties change rapidly over time or where laboratory facilities are unavailable. This paper reports the development and validation of an inexpensive, lightweight and robust 'open source' extensional rheometer, Seymour II. Validation was carried out experimentally and computationally. Measurements on a Newtonian fluid (492 mPa s Brookfield silicone oil) yielded results of 510  ±  51 mPa s; these are comfortably within the range of  ±10% which other authors have quoted for extensional techniques using laboratory rheometers. Comparison of the observed filament thinning dynamics to those obtained using computational fluid dynamics (CFD) gave good qualitative agreement. Use of Seymour II at the University of Cambridge Botanic Gardens revealed that the mucilage of the 'crane flower', $\textit{Strelitzia reginae}$, was a viscoelastic fluid whose extensional response could be described by a two-mode Giesekus equation. Engineering drawings and image analysis code for Seymour II are available for download at the project website, www.seymourII.org/.Support for a summer internship for NP from ENSTA, a PhD studentship for MPB from Sandvik Hyperion and Ceratizit, and a PhD studentship for OMM from Chemours

Rupture by damage accumulation in rocks

The deformation of rocks is associated with microcracks nucleation and propagation, i.e. damage. The accumulation of damage and its spatial localization lead to the creation of a macroscale discontinuity, so-called "fault" in geological terms, and to the failure of the material, i.e. a dramatic decrease of the mechanical properties as strength and modulus. The damage process can be studied both statically by direct observation of thin sections and dynamically by recording acoustic waves emitted by crack propagation (acoustic emission). Here we first review such observations concerning geological objects over scales ranging from the laboratory sample scale (dm) to seismically active faults (km), including cliffs and rock masses (Dm, hm). These observations reveal complex patterns in both space (fractal properties of damage structures as roughness and gouge), time (clustering, particular trends when the failure approaches) and energy domains (power-law distributions of energy release bursts). We use a numerical model based on progressive damage within an elastic interaction framework which allows us to simulate these observations. This study shows that the failure in rocks can be the result of damage accumulation

'Drowning in here in his bloody sea' : exploring TV cop drama's representations of the impact of stress in modern policing

The Criminal Justice System is a part of society that is both familiar and hidden. It is familiar in that a large part of daily news and television drama is devoted to it (Carrabine, 2008; Jewkes, 2011). It is hidden in the sense that the majority of the population have little, if any, direct contact with the Criminal Justice System, meaning that the media may be a major force in shaping their views on crime and policing (Carrabine, 2008). As Reiner (2000) notes, the debate about the relationship between the media, policing, and crime has been a key feature of wider societal concerns about crime since the establishment of the modern police force. He outlines the recurring themes in post-war debates in this field. For Conservatives there has been an ongoing concern that the media is criminongenic, as it serves to undermine traditional institutions, including the police. From the viewpoint of radical criminology, the impact of the media is two-fold: it exaggerates legitimate concerns about crime and emphasises the bureaucratic and other restrictions under which the police operate (Reiner, 2000). This is seen as undermining due process and legitimatising what can be termed a ‘maverick’ approach to policing. An early example of this can be seen in Clint Eastwood’s Dirty Harry movies (Siegel, 1971) where Harry Callaghan acts as a one-man law enforcement system outside of the formal legal process, a process portrayed as corrupt, inefficient, and concerned with offenders’ rights rather than protecting victims. From a policing perspective, Reiner (2000) argues that film and TV drama creates a simplistic narrative of crime solving that is almost completely divorced from the reality of modern police work, a finding consistent with more recent work by Cummins et al., (2014)

Albert Pierrepoint and the cultural persona of the twentieth-century hangman

Albert Pierrepoint was Britain’s most famous 20th-century hangman. This article utilises diverse sources in order to chart his public representation, or cultural persona, as hangman from his rise to prominence in the mid-1940s to his portrayal in the biopic Pierrepoint(2005). It argues that Pierrepoint exercised agency in shaping this persona through publishing his autobiography and engagement with the media, although there were also representations that he did not influence. In particular, it explores three iterations of his cultural persona – the Professional Hangman, the Reformed Hangman and the Haunted Hangman. Each of these built on and reworked historical antecedents and also communicated wider understandings and contested meanings in relation to capital punishment. As a hangman who remained in the public eye after the death penalty in Britain was abolished, Pierrepoint was an important, authentic link to the practice of execution and a symbolic figure in debates over reintroduction. In the 21st century, he was portrayed as a victim of the ‘secondary trauma’ of the death penalty, which resonated with worldwide campaigns for abolition