Fast design optimization of UWB antenna with WLAN Band-Notch

In this paper, a methodology for rapid design optimization of an ultra-wideband ( UWB) monopole antenna with a lower WLAN band-notch is presented. The band-notch is realized using an open loop resonator implemented in the radiation patch of the antenna. Design optimization is a two stage process, with the first stage focused on the design of the antenna itself, and the second stage aiming at identification of the appropriate dimensions of the resonator with the purpose of allocating the band-notch in the desired frequency range. Both optimization stages are realized using surrogate-based optimization involving variable-fidelity electromagnetic ( EM) simulation models as well as an additive response correction ( first stage), and sequential approximate optimization ( second stage). The final antenna design is obtained at the CPU cost corresponding to only 23 high-fidelity EM antenna simulations

Cost-efficient modeling of antenna structures using Gradient Enhanced Kriging

Reliable yet fast surrogate models are indispensable in the design of contemporary antenna structures. Data-driven models, e.g., based on Gaussian Processes or support-vector regression, offer sufficient flexibility and speed, however, their setup cost is large and grows very quickly with the dimensionality of the design space. In this paper, we propose cost-efficient modeling of antenna structures using Gradient-Enhanced Kriging. In our approach, the training data set contains, apart from the EM-simulation responses of the structure at hand, also derivative data at the respective training locations obtained at little extra cost using adjoint sensitivity techniques. We demonstrate that introduction of the derivative information into the model allows for considerable reduction of the model setup cost (in terms of the number of training points required) without compromising its predictive power. The Gradient-Enhanced Kriging technique is illustrated using a dielectric resonator antenna structure. Comparison with conventional Kriging interpolation is also provided

To Assess the Stromal Expression of CD10 in Invasive Ductal Carcinoma of Breast and It’s Correlation with Histological Grade, ER, PR AND HER2/neu Expression

BACKGROUND : Breast cancer is the most common cancer among women in India according to National cancer registry programme 2011 report. Stroma has a important role in the pathogenesis of carcinoma of breast. Stromal marker can be novel marker for assessing the prognosis of breast cancer which is increasing in incidence. AIM : The present study aims to study the expression of CD10 in stroma of invasive ductal carcinoma of breast NOS type and to assess its relationship with histopathological grade, hormonal receptor status and HER2/neu overexpression. MATERIALS AND METHODS : With the representative sections of 30 IDC NOS type hematoxylin and eosin staining was done. Immunohistochemistry was done with ER, PR, HER2 and CD10. CD10 expression in stroma (>30% stromal positivity was considered positive) of invasive ductal carcinoma was studied and statistically analyzed with histopathological grade, ER, PR and HER2/neu. RESULTS : 73% (22/30) cases showed positivity for stromal CD10, (46% (14) strongly positive and 27% (8) weakly positive). 92% (13/14) of CD10 positive cases were negative for ER and PR. 71% (10/14) of CD10 positive cases showed HER2/neu positivity. 77% (10/13) of CD10 positive cases were high grade carcinomas. CD10 expression was significantly associated with ER and PR negativity ( P value<0.05), HER2/neu positivity and higher grade (P value <0.05). CONCLUSION : Stromal CD10 expression is inversely correlated with hormonal receptors and directly correlated with higher tumor grade and HER2 positivity. CD10 could be used as novel prognostic marker in carcinoma of breast and used for drug development. Further studies are needed to assess the effect of chemotherapy on CD10 status, to correlate with chemotherapeutic response

Posterior Uterine Rupture Causing Fetal Expulsion into the Abdominal Cavity: A Rare Case of Neonatal Survival

Introduction. Uterine rupture is a potentially catastrophic complication of vaginal birth after caesarean section. We describe the sixth case of posterior uterine rupture, with intact lower segment scar, and the first neonatal survival after expulsion into the abdominal cavity with posterior rupture. Case Presentation. A multiparous woman underwent prostaglandin induction of labour for postmaturity, after one previous caesarean section. Emergency caesarean section for bradycardia revealed a complete posterior uterine rupture, with fetal and placental expulsion. Upon delivery, the baby required inflation breaths only. The patient required a subtotal hysterectomy but returned home on day 5 postnatally with her healthy baby. Discussion. Vaginal birth after caesarean section constitutes a trial of labour, and the obstetrician must be reactive to labour events. Posterior uterine rupture is extremely rare and may occur without conventional signs. Good maternal and fetal outcome is possible with a prompt, coordinated team response

An analysis of stromal expression of CD10 in invasive ductal carcinoma of breast and its correlation with histological grade

Background: Breast cancer is one of the most common cancers among women in India. Stroma has an important role in the pathogenesis of carcinoma of breast. Stromal marker can be novel marker for assessing the prognosis of breast cancer.Methods: With the representative sections of 30 invasive ductal carcinoma of breast NOS type Hematoxylin and eosin staining was done. Immunohistochemistry was done with CD10. CD10 expression in stroma in cases and control slides were studied and statistically analyzed with histopathological grade.Results: 46% (14 out of 30) of cases showed strong positivity for stromal CD10. Only two cases of strong positivity for CD10 were noted in the adjacent normal breast parenchyma. Stromal expression of CD10 had a statistically significant association with breast carcinoma than in control slides, p value is 0.002. 77% (10 out of 13) of CD10 positive cases were high grade carcinomas. Association of CD10 expression with high grade tumour was statistically significant (p value is 0.04 which is less than 0.05). No association was found with mean age.Conclusions: As the grade of breast carcinoma increases the stromal expression of CD10 is increased. Stromal CD10 expression is directly correlated with higher tumour grade. CD10 could be used as novel prognostic marker and used to develop newer drugs.

(2E,4E)-Ethyl 5-(phenyl­sulfon­yl)penta-2,4-dienoate

In the title compound, C13H14O4S, both C=C double bonds adopt an E conformation. In the crystal, mol­ecules are linked into centrosymmetric R 2 2(14) dimers via pairs of C—H⋯O hydrogen bonds

Ethyl (E)-3-[1′-ethyl-2-oxo-4′-(phenyl­sulfon­yl)-2H-spiro­[acenaphthyl­ene-1,2′-pyrrolidine]-3′-yl]acrylate

In the title compound, C28H27NO5S, the five-membered pyrrolidine ring, which exhibits an envelope conformation (the C atom at the spiral junction being the flap atom), makes dihedral angles of 57.37 (10) and 86.84 (8)°, respectively, with the phenyl ring and the acenaphthyl­ene ring system. In the crystal, mol­ecules associate via two C—H⋯O hydrogen bonds, forming R 2 2(20) and R 2 2(10) graph-set motifs

Ssr-based molecular profiling of selected donors of wide compatibility, elongated uppermost internode, stigma exsertion and submergence tolerance traits and parental lines of commercial rice (o. Sativa l.) Hybrids

Molecular breeding plays an important role in sustainable agriculture development. Hybrid rice technology aims to increase the yield potential of rice beyond the level of inbred high-yielding varieties (HYVs) by exploiting the phenomenon of hybrid vigour or heterosis. Improvement of hybrid rice parental line is necessary to meet the food security problem. Parental polymorphism was carried with 215 SSR markers between five recurrents and ten donors. During the foreground selection, both reported markers (S5-Indel and BF-S5) were validated for wide compatibility, 2 out of 14 (ART5 and SC3) validates for submergence tolerance, one out of two (RM5) validate for stigma exsertion, whereas 2 of 3 markers (RM5970, RM3476) validated for elongated uppermost internode traits between recurrents and donors. For background selection, maximum polymorphic markers (112) between IR58025eB i.e improved maintainer line with elongated uppermost internode and Oryza meridionalis and minimum polymorphic markers (42) between IR79156B and IR91-1591-3 were found. Marker-assisted backcrossing accelerate, the transfer of gene of interest in desirable genetic background. Genotypes IR58025B and IR58025eB emerged as genetically most similar with a value of 97%. The genotypes IR64 Sub1 and Oryza meridionalis were found most divergent showing 33% genetic similarity. Dissimilarity coefficient of the generated information obtained on genetic relatedness would be supportive in further rice breeding program

Marker-Assisted Improvement of the Elite Maintainer Line of Rice, IR 58025B for Wide Compatibility (S5n) Gene

The degree of heterosis in different hybrid rice varieties is reported to be at the highest in indica/japonica cross combination, however, there is a problem of sterility and semi-sterility in such inter sub specific hybrids. To overcome this problem, it is essential to develop parental lines having wide compatibility (S5n) gene. In this study, a functional marker S5-InDel was used for marker-assisted backcrossing (MABB) to introgress S5n gene from Dular into the genetic background of a widely grown recurrent parent IR 58025B, a maintainer line of wild-abortive (WA) cytoplasmic male sterile line, IR 58025A. Further, a closely linked marker nksbadh2 was used for the identification of plants devoid of aroma in backcross population to develop hybrids with no aroma. The stringent phenotypic selection followed by background selection of BC3F4 identified plants with 94.51–98.90% of the recurrent parent genome recovery of lines carrying S5n gene. Subsequently, at 10 promising BC3F5 lines possessing S5n gene with high yielding and long-slender grain type were validated for their maintainer behavior through test crosses with IR 58025A. Also the improved lines showed significantly improved spikelet fertility performance while crossed with japonica and javanica testers in comparison to the original recurrent parent. The improved lines developed in the present study, are being converted to CMS lines through marker-assisted backcross breeding to facilitate precise and improved hybrid breeding program in rice