\uabEvo-devo meets the Mind\ubb. La questione dell\u2019esperienza estetica e l\u2019evoluzionismo contemporaneo, dall\u2019ipotesi degli adattamenti modulari all\u2019interpretazione sistemica dell\u2019omologia

Is it achievable to read aesthetic experience as a modular adaptation, and what would be its implication on the image of man, on aesthetics and on evolutionary theory itself? An alternative path is offered by evolutionary morphology, starting from the elaboration of a biologic concept of organism and from the notion of homology of function as a system of interconnections organized in a hierarchy. We deduce the possibility of thinking the peculiar innovation of aesthetic experience in an evolutionary way

TIPO, FORMA, MEMORIA. BUFFON E IL PROBLEMA DELLA D\uc9G\uc9N\uc9RATION

The concept of d\ue9g\ue9n\ue9ration in Buffon plays a key role in allowing to articulate a reflection on the relationship between species and individual, in theorizing the unit of the type as hierarchical concept of higher order capable of giving an account of the reality of life in its diversification, and especially in allowing the arising of a consideration of the relationship between matter and living form that will profoundly affect the origins of modern biology as Goethe\u2019s morphological thinking

Bild unserer irren Anwesenheit / auf der Oberfl\ue4che der Erde. L\u2019immagine come storia naturale del presente nella poetica di W. G. Sebald

The poem Nach der Natur by W. G. Sebald, real germinal place of its author\u2019s subsequent literary production, is a salient moment of confrontation for today's philosophical gaze; our historical time and our own humanity are configured as \u201cnatural history\u201d (Benjamin), in a compositional game in which the present time acquires the character of a timeless distance projecting it on the background of a mournful nature, entrusting to the roughness of the poetic material and to its conceptual weaving the task of an unprecedented presentification of some layers of reality of rare density

Somaesthetics as a Discipline Between Pragmatist Philosophy and Philosophical Anthropology

Richard Shusterman\u2019s somaesthetics provides a disciplinary framework in which come together reflections on the body by the main philosophical traditions of the twentieth century; the paper investigates some relations with Plessner and philosophical anthropology, as well as the rediscovery of some of the themes of Baumgarten\u2019s aesthetics

Erweiterung des Kantismus, Umgestaltung der Metaphysik. Il giovane Viktor von Weizs\ue4cker lettore di Kant

This paper aims to examine the relationships between the research of young Viktor von Weizs\ue4cker and Kant\u2019s critical thinking. Since the criticism of Driesch\u2019s Neovitalism, are considered some of the major contributions of Weizsacker in the years 1911-1926, in order to show its path between criticism of knowledge, metaphysics, construction of a biology and a medical anthropolog

Advanced models of human skeletal muscle differentiation, development and disease: Three-dimensional cultures, organoids and beyond

Advanced in vitro models of human skeletal muscle tissue are increasingly needed to model complex developmental dynamics and disease mechanisms not recapitulated in animal models or in conventional monolayer cell cultures. There has been impressive progress towards creating such models by using tissue engineering approaches to recapitulate a range of physical and biochemical components of native human skeletal muscle tissue. In this review, we discuss recent studies focussed on developing complex in vitro models of human skeletal muscle beyond monolayer cell cultures, involving skeletal myogenic differentiation from human primary myoblasts or pluripotent stem cells, often in the presence of structural scaffolding support. We conclude with our outlook on the future of advanced skeletal muscle three-dimensional cultures (e.g. organoids and biofabrication) to produce physiologically and clinically relevant platforms for disease modelling and therapy development in musculoskeletal and neuromuscular disorders

On the calibration of the relation between geometric albedo and polarimetric properties for the asteroids

We present a new extensive analysis of the old problem of finding a satisfactory calibration of the relation between the geometric albedo and some measurable polarization properties of the asteroids. To achieve our goals, we use all polarimetric data at our disposal. For the purposes of calibration, we use a limited sample of objects for which we can be confident to know the albedo with good accuracy, according to previous investigations of other authors. We find a new set of updated calibration coefficients for the classical slope - albedo relation, but we generalize our analysis and we consider also alternative possibilities, including the use of other polarimetric parameters, one being proposed here for the first time, and the possibility to exclude from best-fit analyzes the asteroids having low albedos. We also consider a possible parabolic fit of the whole set of data.Comment: Accepted by MNRA