5,936 research outputs found

    Subtraction Menger algebras

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    Abstract characterizations of Menger algebras of partial nn-place functions defined on a set AA and closed under the set-theoretic difference functions treatment as subsets of the Cartesian product An+1A^{n+1} are given

    Biased Information Search in Homogeneous Groups: Confidence as a Moderator for the Effect of Anticipated Task Requirements

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    When searching for information, groups that are homogeneous regarding their members’ prediscussion decision preferences show a strong bias for information that supports rather than conflicts with the prevailing opinion (confirmation bias). The present research examined whether homogeneous groups blindly search for information confirming their beliefs irrespective of the anticipated task or whether they are sensitive to the usefulness of new information for this forthcoming task. Results of three experiments show that task sensitivity depends on the groups’ confidence in the correctness of their decision: Moderately confident groups displayed a strong confirmation bias when they anticipated having to give reasons for their decision but showed a balanced information search or even a disconfirmation bias (i.e., predominately seeking conflicting information) when they anticipated having to refute unterarguments. In contrast, highly confident groups demonstrated a strong confirmation bias independent of the anticipated task requirements

    The relation of semiadjacency of \cap-semigroups of transformations

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    We consider two relations on a \cap-semigroup of partial functions of a given set: the inclusion of domains and the semiadjacencity (i.e., the inclusion of the image of the first function into the domain of the second), which characterized with an abstract point of view using the elementary system of axioms, i.e., system conditions, recorded in the language narrow predicate calculus with equality

    Traversable Wormholes in Geometries of Charged Shells

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    We construct a static axisymmetric wormhole from the gravitational field of two charged shells which are kept in equilibrium by their electromagnetic repulsion. For large separations the exterior tends to the Majumdar-Papapetrou spacetime of two charged particles. The interior of the wormhole is a Reissner-Nordstr\"om black hole matching to the two shells. The wormhole is traversable and connects to the same asymptotics without violation of energy conditions. However, every point in the Majumdar-Papapetrou region lies on a closed timelike curve.Comment: 9 pages, LaTeX, 1 figur

    Computational selection of inhibitors of Abeta aggregation and neuronal toxicity.

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    Alzheimer\u27s disease (AD) is characterized by the cerebral accumulation of misfolded and aggregated amyloid-beta protein (Abeta). Disease symptoms can be alleviated, in vitro and in vivo, by \u27beta-sheet breaker\u27 pentapeptides that reduce plaque load. However the peptide nature of these compounds, made them biologically unstable and unable to penetrate membranes with high efficiency. The main goal of this study was to use computational methods to identify small molecule mimetics with better drug-like properties. For this purpose, the docked conformations of the active peptides were used to identify compounds with similar activities. A series of related beta-sheet breaker peptides were docked to solid state NMR structures of a fibrillar form of Abeta. The lowest energy conformations of the active peptides were used to design three dimensional (3D)-pharmacophores, suitable for screening the NCI database with Unity. Small molecular weight compounds with physicochemical features and a conformation similar to the active peptides were selected, ranked by docking and biochemical parameters. Of 16 diverse compounds selected for experimental screening, 2 prevented and reversed Abeta aggregation at 2-3microM concentration, as measured by Thioflavin T (ThT) fluorescence and ELISA assays. They also prevented the toxic effects of aggregated Abeta on neuroblastoma cells. Their low molecular weight and aqueous solubility makes them promising lead compounds for treating AD

    Representations of (2,n)(2,n)-semigroups by multiplace functions

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    We describe the representations of (2,n)(2,n)-semigroups, i.e. groupoids with nn binary associative operations, by partial nn-place functions and prove that any such representation is a union of some family of representations induced by Schein's determining pairs.Comment: 17 page

    Representations of Menger (2,n)(2,n)-semigroups by multiplace functions

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    Investigation of partial multiplace functions by algebraic methods plays an important role in modern mathematics were we consider various operations on sets of functions, which are naturally defined. The basic operation for nn-place functions is an (n+1)(n+1)-ary superposition [][ ], but there are some other naturally defined operations, which are also worth of consideration. In this paper we consider binary Mann's compositions \op{1},...,\op{n} for partial nn-place functions, which have many important applications for the study of binary and nn-ary operations. We present methods of representations of such algebras by nn-place functions and find an abstract characterization of the set of nn-place functions closed with respect to the set-theoretic inclusion

    The Cosmic Censor Forbids Naked Topology

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    For any asymptotically flat spacetime with a suitable causal structure obeying (a weak form of) Penrose's cosmic censorship conjecture and satisfying conditions guaranteeing focusing of complete null geodesics, we prove that active topological censorship holds. We do not assume global hyperbolicity, and therefore make no use of Cauchy surfaces and their topology. Instead, we replace this with two underlying assumptions concerning the causal structure: that no compact set can signal to arbitrarily small neighbourhoods of spatial infinity (``i0i^0-avoidance''), and that no future incomplete null geodesic is visible from future null infinity. We show that these and the focusing condition together imply that the domain of outer communications is simply connected. Furthermore, we prove lemmas which have as a consequence that if a future incomplete null geodesic were visible from infinity, then given our i0i^0-avoidance assumption, it would also be visible from points of spacetime that can communicate with infinity, and so would signify a true naked singularity.Comment: To appear in CQG, this improved version contains minor revisions to incorporate referee's suggestions. Two revised references. Plain TeX, 12 page

    More than a cognitive experience: unfamiliarity, invalidation, and emotion in organizational learning

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    Literature on organizational learning (OL) lacks an integrative framework that captures the emotions involved as OL proceeds. Drawing on personal construct theory, we suggest that organizations learn where their members reconstrue meaning around questions of strategic significance for the organization. In this 5-year study of an electronics company, we explore the way in which emotions change as members perceive progress or a lack of progress around strategic themes. Our framework also takes into account whether OL involves experiences that are familiar or unfamiliar and the implications for emotions. We detected similar patterns of emotion arising over time for three different themes in our data, thereby adding to OL perspectives that are predominantly cognitive in orientation

    Inverse monoids and immersions of 2-complexes

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    It is well known that under mild conditions on a connected topological space X\mathcal X, connected covers of X\mathcal X may be classified via conjugacy classes of subgroups of the fundamental group of X\mathcal X. In this paper, we extend these results to the study of immersions into 2-dimensional CW-complexes. An immersion f:DCf : {\mathcal D} \rightarrow \mathcal C between CW-complexes is a cellular map such that each point yDy \in {\mathcal D} has a neighborhood UU that is mapped homeomorphically onto f(U)f(U) by ff. In order to classify immersions into a 2-dimensional CW-complex C\mathcal C, we need to replace the fundamental group of C\mathcal C by an appropriate inverse monoid. We show how conjugacy classes of the closed inverse submonoids of this inverse monoid may be used to classify connected immersions into the complex
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