Photoresponse of wafer-scale palladium diselenide films prepared by selenization method

202308 bcvcAccepted ManuscriptOthersThe Hong Kong Polytechnic UniversityPublishe

In situ observation of the thermal stability of black phosphorus

202308 bcvcAccepted ManuscriptOthersThe Hong Kong Polytechnic University; Soochow University; The NSFCPublishe

Ferroelectricity in untwisted heterobilayers of transition metal dichalcogenides

202208 bcrcVersion of RecordRGCOthersOthers: National Natural Science Foundation of ChinaHong Kong Polytechnic UniversityPublishe

Impurity-induced robust trionic effect in layered violet phosphorus

202210 bcfcRGCOthersThe Hong Kong Polytechnic UniversityPublished12 month

Hepatitis E Virus Exposure is Increased in Pork Butchers from Burkina Faso

International audienceWe conducted the first survey of zoonotic risk of Hepatitis E virus (REV) transmissions in Ouagadougou, Burkina Faso, through the direct contact with pork meat during professional activity. Anti-REV antibodies were more prevalent in pork butchers, 76% than in the general population, which was 47.8% in 2013 (odds ratio = 3.46, 95% CI = 2.85-4.21, P < 0.001). Among slaughter-aged swine, REV seroprevalence was of 80%, and REV RNA was detected in 1% of pork livers. Phylogenetic analysis pointed out HEV genotype 3. Thus, in addition to possible HEV contamination through the water source, as in endemic region, zoonotic transmissions of REV probably occur in west Africa

Enhancement of photo-electrochemical reactions in MAPbI3/Au

201811 bcmaAccepted ManuscriptRGCOthersThe Hong Kong Polytechnic UniversityPublishe

Influence of chimeric human-bovine fibers on adenoviral uptake by liver cells and the antiviral immune response

International audienceHuman adenoviruses (HAdV) are widely used for in vitro and in vivo gene transfer. Viral hepatotropism, inflammatory responses and neutralization by pre-existing antibodies (NAbs) are obstacles for clinical applications of HAdV vectors. Although the multifactorial events leading to innate HAdV toxicity are far from being elucidated, there is a consensus that the majority of intravenously injected-HAdV vectors is sequestered by Kuppfer cells, probably independently of coagulation factors. In this study, we show that the adenoviral-associated humoral and innate cytokine immune responses are significantly reduced when HAdV-5 vector carrying human bovine chimeric fibers (HAdV-5-F2/BAdV-4) is intravenously injected into mice. Fiber pseudotyping modified its interaction with blood coagulation factors, as FIX and FX no longer mediate the infection of liver cells by HAdV-5-F2/BAdV-4. As a consequence, at early time points post-infection, several cytokines and chemokines (IFN-gamma, IL-6, IP-10, MCP-1, RANTES and MP1beta) were found to be present at lower levels in the plasma of mice that had been intravenously injected with HAdV-5-F2/BAdV-4 compared with mice injected with the parental vector HAdV-5. Moreover, genetic modification of the fiber allowed HAdV-5-F2/BAdV-4 to partially escape neutralization by NAbs