1,225 research outputs found

    Control-structure interaction in a free beam

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    A simple energy approach to study the problem of control structure interactions in large space structures is presented. For the illustrative case of a free-free beam, the vibrational energy imparted during operation of constant, step, and pulsed thrusters is found in a nondimensional closed form. Then based on a parametric study, suggestions are made on the choice of parameters to minimize the control structure interactions. The study of this simple system provides physical insight and understanding for more complex systems

    Orthosis reduces breast pain and mechanical forces through natural and augmented breast tissue in women lying prone

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    BACKGROUND: Breast implant displacement or rupture can cause aesthetic problems and serious medical complications. Activities with prone positioning and loading of the anterior chest wall, such as massage, chiropractic or osteopathic therapies may increase the risk of implant failure and can also cause discomfort in women with natural breast tissue. Here we test the effectiveness of a newly developed orthosis on pain, mechanical pressure and displacement of breast tissue in women with cosmetic augmentation, post-mastectomy reconstruction, lactating or natural breast tissue. METHODS: Thirty-two females volunteers, aged 25–56 years with augmented, reconstructed, natural or lactating breast tissue and cup sizes B-F, participated in this open-label clinical trial. We measured pain perception, peak pressure, maximum force, and breast tissue displacement using different sizes of the orthosis compared to no orthosis. Different densities of the orthosis were also tested in a subgroup of women (n = 7). Pain perception was rated using a validated 11-point visual-analogue scale. Peak pressure and maximum force were assessed using a bilateral set of capacitance-pliance® sensor strips whilst participants were load bearing in a prone position, and breast displacement was measured by magnetic-resonance-imaging. RESULTS: The orthosis significantly reduced pain, breast displacement and mechanical pressures in women with natural and augmented breast tissue in prone position. Greater relief of pain and greater reduction in mechanical forces were found with increased size and density of the orthosis. Use of the orthosis improved overall comfort by 64-100%, lowered peak pressure by up to 85% and maximum force by up to 96%. Medio-lateral displacement of breast tissue was reduced by 16%, resulting in a 51% desirable increase of breast tissue height. CONCLUSION: Our study demonstrated that the newly developed orthosis significantly reduced pain, mechanical pressure and breast tissue displacement in women with augmented and natural breast tissue when lying prone. Our findings are of clinical significance, potentially reducing the risk of complication from prone activities in women with breast augmentation or reconstruction, as well as improving comfort whilst undergoing prone procedures. TRIAL REGISTRATION: Australia and New Zealand Clinical Trials Register, ACTRN12613000541707

    Phenotype set enrichment analysis

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    Space Shuttle orbiter entry heating and TPS response: STS-1 predictions and flight data

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    Aerothermodynamic development flight test data from the first orbital flight test of the Space Transportation System (STS) transmitted after entry blackout is given. Engineering predictions of boundary layer transition and numerical simulations of the orbiter flow field were confirmed. The data tended to substantiate preflight predictions of surface catalysis phenomena. The thermal response of the thermal protection system was as expected. The only exception is that internal free convection was found to be significant in limiting the peak temperature of the structure in areas which do not have internal insulation

    A strategy for the characterization of minute chromosome rearrangements using multiple color fluorescence in situ hybridization with chromosome-specific DNA libraries and YAC clones

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    The identification of marker chromosomes in clinical and tumor cytogenetics by chromosome banding analysis can create problems. In this study, we present a strategy to define minute chromosomal rearrangements by multicolor fluorescence in situ hybridization (FISH) with whole chromosome painting probes derived from chromosome-specific DNA libraries and Alu-polymerase chain reaction (PCR) products of various region-specific yeast artificial chromosome (YAC) clones. To demonstrate the usefulness of this strategy for the characterization of chromosome rearrangements unidentifiable by banding techniques, an 8p+ marker chromosome with two extra bands present in the karyotype of a child with multiple anomalies, malformations, and severe mental retardation was investigated. A series of seven-color FISH experiments with sets of fluorochrome-labeled DNA library probes from flow-sorted chromosomes demonstrated that the additional segment on 8p+ was derived from chromosome 6. For a more detailed characterization of the marker chromosome, three-color FISH experiments with library probes specific to chromosomes 6 and 8 were performed in combination with newly established telomeric and subtelomeric YAC clones from 6q25, 6p23, and 8p23. These experiments demonstrated a trisomy 6pter6p22 and a monosomy 8pter8p23 in the patient. The present limitations for a broad application of this strategy and its possible improvements are discusse

    Weakly Nonlinear Analysis of Electroconvection in a Suspended Fluid Film

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    It has been experimentally observed that weakly conducting suspended films of smectic liquid crystals undergo electroconvection when subjected to a large enough potential difference. The resulting counter-rotating vortices form a very simple convection pattern and exhibit a variety of interesting nonlinear effects. The linear stability problem for this system has recently been solved. The convection mechanism, which involves charge separation at the free surfaces of the film, is applicable to any sufficiently two-dimensional fluid. In this paper, we derive an amplitude equation which describes the weakly nonlinear regime, by starting from the basic electrohydrodynamic equations. This regime has been the subject of several recent experimental studies. The lowest order amplitude equation we derive is of the Ginzburg-Landau form, and describes a forward bifurcation as is observed experimentally. The coefficients of the amplitude equation are calculated and compared with the values independently deduced from the linear stability calculation.Comment: 26 pages, 2 included eps figures, submitted to Phys Rev E. For more information, see http://mobydick.physics.utoronto.c

    Electroconvection in a Suspended Fluid Film: A Linear Stability Analysis

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    A suspended fluid film with two free surfaces convects when a sufficiently large voltage is applied across it. We present a linear stability analysis for this system. The forces driving convection are due to the interaction of the applied electric field with space charge which develops near the free surfaces. Our analysis is similar to that for the two-dimensional B\'enard problem, but with important differences due to coupling between the charge distribution and the field. We find the neutral stability boundary of a dimensionless control parameter R{\cal R} as a function of the dimensionless wave number κ{\kappa}. R{\cal R}, which is proportional to the square of the applied voltage, is analogous to the Rayleigh number. The critical values Rc{{\cal R}_c} and κc{\kappa_c} are found from the minimum of the stability boundary, and its curvature at the minimum gives the correlation length ξ0{\xi_0}. The characteristic time scale τ0{\tau_0}, which depends on a second dimensionless parameter P{\cal P}, analogous to the Prandtl number, is determined from the linear growth rate near onset. ξ0{\xi_0} and τ0{\tau_0} are coefficients in the Ginzburg-Landau amplitude equation which describes the flow pattern near onset in this system. We compare our results to recent experiments.Comment: 36 pages, 7 included eps figures, submitted to Phys Rev E. For more info, see http://mobydick.physics.utoronto.ca

    Sexual knowledge, attitudes, and behavior and attitudes toward feminism : a cross cultural study

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    The purpose of this study was to investigate the relationship between feminism and sexuality from a cross-cultural perspective. It was hypothesized that women who had a liberal attitude toward feminism would have more knowledge about sexuality and have more liberal sexual attitudes with regard to (a) heterosexual relations, (b) sexual myths, (c) abortion, and (d) autoeroticism; and more liberal sexual behaviors with regard to (a) the number of times having had sexual intercourse, (b) the number of sexual partners, and (c) participation in masturbatory activity. It was also hypothesized that Israeli women would have more knowledge about sexuality and more liberal sexual attitudes and behaviors than American women on the above-named measures. It was further hypothesized that there would be no difference between American and Israeli women in their attitudes toward feminism. The subjects were 90 American and 90 Israeli Jewish, female, social work students who were interested in cooperating in the study. Two self-administered questionnaires were used, the Sex Attitude and Knowledge Inventory and the Feminism Attitude Scale
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