Nanotechnology Revolutionized Human Civic

Nanotechnology could bring about a life-changing revolution in human life, this vision of nanoscience ultimately combines the science and engineering of man-made and biological entities, controlled at the nanometre scale, and assembled into complex, engineered structures that can interact with their surroundings at dimensions ranging from that of molecules to that of humans and beyond.Nanotechnology is necessarily a multidisciplinary field which encompasses and draws from the knowledge of several diverse technological fields of study including chemistry, physics, molecular biology, material science, computer science, and engineeringnanotechnology is becoming ever more deeply embedded in today’s life, so it is a critical moment for communicating the huge public ,for its importance ,this study highlights the use of nanotechnology in all aspects for the human development like medical fields ,environment maintenance, drug deliveryand also lead role in evolution development, Industrial applications include sensing as biosensors in textiles, electronics and the life sciences industries. This paper mostly highlights the research in nanotechnology will connoisseur the existence on earth

How do programs work to improve child nutrition?: Program impact pathways of three nongovernmental organization intervention projects in the Peruvian highlands

This paper examines the program logic of three nongovernmental, community-based programs with different intervention models to reduce childhood stunting. Two programs, Child Nutrition Program (PNI) and Good Start, focused directly on education and behavior change among caregivers, or the short routes to achieve impact, while one program, Sustainable Networks for Food Security (REDESA), focused on upstream factors, such as improving local governance and coordination, improving water and sanitation, and increasing family incomes, or the long routes to achieve impact. We compared the logic of each program as it was explicitly documented to the logic as perceived by the implementers. We elucidated the program impact pathways (PIPs) of key activities by actors at different operational levels in each program to identify congruencies and gaps in the perceptions of causal mechanisms between program activities and their intended outcomes, and analyzed them with the simple program models and logical frameworks to highlight the methodology and utility of PIPs. In a desire to move beyond static input-out models of the three programs, we designed and conducted data collection activities (document review, semi-structured interviews, and observations) with the intention of gaining insights about those aspects of the program that brought causal mechanisms of a given program into clearer focus. We propose that different methods for eliciting PIPs may be necessary at different operational levels. The interview method elicited more complete responses among those who are familiar with programmatic concepts, whereas actors at the local operational level provided sparse and fragmentary responses, even when simple, common language was used during the interviews. Group participatory processes, using visual aids, may be more effective for mapping the perceptions of those who are not accustomed to articulating information about programs. To reduce the length and frequency of interviews with program actors, initial PIPs could also be constructed from program documents, then discussed and revised iteratively with program actors. Although program logic models and the logical frameworks provide a succinct overview of the program (for communication, strategic planning, and management), we found that PIPs provide a better representation of the causal connections between program activities and results, particularly when both upstream and direct intervention activities were part of the same program. PIPs provide a visual tool for tracking how activities were perceived to work and make an impact, bringing into focus the different pathways of the activities and influences along the way. Beyond the logical sequence of program inputs, outputs, and outcomes, the conceptualization of impact pathways is a useful approach for understanding the causal connections required for impact and for identifying where attention and reinforcements may be required within program operation. The utility of this tool warrants its use not only during final evaluation but also during mid-program monitoring and relevant assessments. National- and regional-level program actors had good understanding of the overarching frameworks and principles of their respective programs as well as the program components and activities. They demonstrated a strong coherence to the program documents, provided similar cohesive responses, and were able to articulate the impact pathways. However, program actors at the national level identified fewer facilitators and barriers along the impact pathways than did the local actors, revealing that the practical dimensions of the impact pathways were not as evident to planners and managers farther from the communities. Although program actors at the local level were more apt to provide practical examples of influencing factors or incidents that occur during implementation, they had difficulty fully articulating their perceived PIPs and provided fragmented views of how the activities linked to their outcomes. Similar patterns were found across the three programs. This finding raises the question of desirability of a common understanding of the goals and pathways by which these outcomes are achieved or the acceptability of diversity of perspectives. It is still unclear whether program effectiveness may be improved through greater congruency in the PIPs. Future research should elucidate how congruency of PIPs among program actors across operational levels could be increased, and whether greater congruency would improve program implementation and effectiveness.program impact pathway, program logic model, logical framework, childhood stunting, child nutrition programs,

Giant angioleiomyoma of uterus masquerading as ovarian tumour: a case report

Angioleiomyoma is a rare benign tumour of uterus. We are presenting an unusual case of 45-year-old female with 11 kg giant angioleiomyoma of uterus which was masquerading as ovarian tumour on imaging. Exploratory laparotomy was done which was suggestive of huge lobulated mass arising from the uterus. Hysterectomy with bilateral salpingo-oophorectomy was done. Histopathological examination of specimen was suggestive of uterine subserosal and broad ligament angioleiomyoma of cavernous type. This case is being reported because of its rarity and challenges in diagnosis and management

Examining the Determinants of Sexual Violence Among Young, Married Women in Southern India

The prevalence of sexual violence is increasingly being studied in India. Yet the determinants of sexual violence, irrespective of physical violence, remain largely unexplored. Here the authors identify the determinants of sexual violence, and additionally, explore how the presence of physical violence modifies these determinants. A cross-sectional analysis is conducted using baseline data from a longitudinal study involving young married women attending reproductive health clinics in Southern India. A multivariable logistic regression analysis is conducted to first identify determinants of sexual violence and then repeated after stratifying elements based on presence or absence of physical violence identified from participants’ reports. 36% and 50% of the participants report experiencing sexual and physical violence, respectively. After adjusting for other covariates, women’s partners’ characteristics are found most significantly associated with their odds of experiencing sexual violence. These characteristics include husbands’ primary education, employment as drivers, alcohol consumption, and having multiple sex partners. Women’s contribution to household income also increases their odds of experiencing sexual violence by almost twofold; however, if they are solely responsible for “all” household income, the relationship is found to be protective. Physical violence modifies the determinants of sexual violence, and among women not experiencing physical violence, husbands’ primary education and employment as drivers increase women’s odds of experiencing sexual violence nearly threefold, and women who contribute “all” the household income (n = 62) do not experience sexual violence. These relationships are not significant among women experiencing physical violence. Study findings improve the understanding of the determinants of sexual violence. Future research is needed to examine the risk factors for different types of GBV independently and to tease apart the differences in risk factors depending on women’s experiences. The significance of male partners’ characteristics warrants in-depth research, and in order to promote gender-equitable norms, future interventions need to focus on male behaviors and men’s day-to-day survival challenges, all of which likely influence conflicts in marital relationships

Foetal arrhythmias: an enigma of the missed beats

Background: The synchronised depolarization and repolarisation of the atria and ventricles is achieved by specialised cardiac cells that generate an electrical impulse and propagate it along the conducting system in the myocardial tissue, leading to rhythmic activity of the atria and ventricles. Abnormalities of these rhythms lead to foetal arrhythmia.Methods: A retrospective observational study was conducted in a tertiary care hospital over period of one year to study the course and perinatal outcome of women with foetal arrhythmias.Results: The confinement in the study period was N=4302, of which 207(4.81%) women had foetal congenital malformations. Among them 21(0.48%) women had foetal cardiovascular abnormalities and 6(0.14%) women had foetal arrhythmias. There were two cases of maternal primary Sjogrens syndrome: one with foetal 2nddegree atrioventricular (AV) heart block with 2:1 AV conduction and another with foetal 3rd degree or complete heart block. Others were a case of Atrial premature contractions with compensatory pause, a case of Supraventricular tachycardia, one case of sinus tachycardia with non-immune hydrops and a case of foetal bradyarrhythmia with regular ectopic beats in a case of complex congenital heart disease. The course of these pregnancies, treatment options and perinatal outcome was studied.Conclusions: Foetal echocardiography and Doppler are effective tools for detection and monitoring of foetal arrhythmias. Early and correct diagnoses of arrhythmias help in management of foetal arrhythmias and multidisciplinary team-based approach gives optimum treatment results

Serum estradiol concentrations as a predictor of successful outcome in artificial frozen-thawed embryo transfer cycles

Background: The role of late follicular serum estradiol monitoring in artificial FET cycles remain unclear. The purpose of this study was to evaluate the correlation between serum estradiol levels on the day of starting progesterone supplementation with clinical pregnancy rates in FET cycle.Methods: This was a non-interventional observational cohort study of patients undergoing ICSI followed by FET at Nadkarni hospital and test tube baby center, Killa-Pardi, Gujarat during the period of January 2021 to May 2021. Total 64 cycles were studied and serum estradiol levels were analyzed on the day of starting progesterone supplementation. They were divided into 3 groups based on serum E2 levels (0-25th centile, 25th-75th centile and >75th centile). Chi square/Fisher exact test were used to compare the clinical pregnancy and implantation rates between these groups.Results: Clinical pregnancy and implantation rates in group A, B and C were 68.8%, 78.1%, 75% and 36.98±9.06, 32.03±4.48 and 29.69±5.69 respectively.Conclusions: Serum estradiol levels before progesterone supplementation in FET cycles do not predict the outcome of FET cycle therefore making routine monitoring of serum estradiol in FET cycle of questionable value

Intervention Design Elements Are Associated with Frontline Health Workers\u27 Performance to Deliver Infant and Young Child Nutrition Services in Bangladesh and Vietnam

Background: Frontline health workers (FLWs) are needed for delivering interventions at scale to reduce maternal and child undernutrition, but low- and middle-income countries often face inadequate FLW performance.Objectives: We examined whether and how intervention design elements such as training, supervision, and mass media improved FLW performance in delivering nutrition services.Methods: Survey data were collected in 2010 and 2014 as part of impact evaluations of Alive & Thrive (A&T) interventions to improve infant and young child feeding (IYCF) practices in Bangladesh and Vietnam. FLWs in A&T intensive (A&T-I) areas received specialized IYCF training, job aids, and regular supportive supervision. Those in non-intensive (A&T-NI) areas received standard government training and supervision. There was mass media exposure in both areas. Multiple regression was used to test differences in exposure to intervention design elements and performance outcomes between the 2 program areas. Path analyses were conducted to examine the paths from exposure to performance outcomes measured at FLW and end-user levels.Results: Compared to FLWs in A&T-NI areas, those in A&T-I areas had higher scores in training (by 1.3-3.6 of 10 points), supportive supervision (0.3-3.5 points), and mass media exposure (0.3-3.5 points). These intervention design elements were significantly associated with FLW knowledge and motivation, which in turn improved service delivery. FLW-level performance outcomes contributed to improving end-user-level outcomes such as higher service received (beta = 0.12-1.04 in Bangladesh and 0.11-0.96 in Vietnam) and maternal knowledge (beta = 0.12-0.17 in Bangladesh and 0.04-0.21 in Vietnam).Conclusions: Training, supervision, and mass media exposure can be implemented at large scale and contribute to improved FLW service delivery by enhancing knowledge and motivation, which in turn positively influence mother\u27s service utilization and IYCF knowledge. Training, supervision, and mass media to enhance service provision should be considered when designing interventions. This trial was registered at clinicaltrials.gov as NCT01678716 (Bangladesh) and NCT01676623 (Vietnam)