Dark-matter sterile neutrinos in models with a gauge singlet in the Higgs sector

Sterile neutrino with mass of several keV can be the cosmological dark matter, can explain the observed velocities of pulsars, and can play an important role in the formation of the first stars. We describe the production of sterile neutrinos in a model with an extended Higgs sector, in which the Majorana mass term is generated by the vacuum expectation value of a gauge-singlet Higgs boson. In this model the relic abundance of sterile neutrinos does not necessarily depend on their mixing angles, the free-streaming length can be much smaller than in the case of warm dark matter produced by neutrino oscillations, and, therefore, some of the previously quoted bounds do not apply. The presence of the gauge singlet in the Higgs sector has important implications for the electroweak phase transition, baryogenesis, and the upcoming experiments at the Large Hadron Collider and a Linear Collider.Comment: 12 pages, 7 figure

Final-state interactions in the response of nuclear matter

Final-state interactions in the response of a many-body system to an external probe delivering large momentum are normally described using the eikonal approximation, for the trajectory of the struck particle, and the frozen approximation, for the positions of the spectators. We propose a generalization of this scheme, in which the initial momentum of the struck particle is explicitly taken into account. Numerical calculations of the nuclear matter response at 1 $< |{\bf q}| <$ 2 GeV/c show that the inclusion of this momentum dependence leads to a sizable effect in the low energy tail. Possible implications for the analysis of existing electron-nucleus scattering data are discussed.Comment: 21 pages, 4 figure

Effect of Plant Polyphenols on Adipokine Secretion from Human SGBS Adipocytes

Introduction. Adipose tissue contributes to atherosclerosis with mechanisms related to adipokine secretion. Polyphenols may exhibit antiatherogenic properties. The aim of the study was to investigate the effects of three polyphenols, namely, quercetin, epigallocatechin gallate (EGCG), and resveratrol on adipokine secretion from cultured human adipocytes. Methods. Human SGBS adipocytes were treated with quercetin, EGCG, and resveratrol for 24 and 48 hours. Visfatin, leptin, and adiponectin were measured in the supernatant. Results. Visfatin secretion was inhibited by quercetin 10 μM by 16% and 24% at 24 and 48 hours respectively. The corresponding changes for quercetin 25 μM were 47% and 48%. Resveratrol 25 μM reduced visfatin by 28% and 38% at 24 and 48 hours. EGCG did not have an effect on visfatin. None of tested polyphenols influenced leptin and adiponectin secretion. Conclusion. Quercetin and resveratrol significantly decreased visfatin secretion from SGBS adipocytes. This effect may contribute to their overall antiatherogenic properties

Affleck-Dine dynamics and the dark sector of pangenesis

Pangenesis is the mechanism for jointly producing the visible and dark matter asymmetries via Affleck-Dine dynamics in a baryon-symmetric universe. The baryon-symmetric feature means that the dark asymmetry cancels the visible baryon asymmetry and thus enforces a tight relationship between the visible and dark matter number densities. The purpose of this paper is to analyse the general dynamics of this scenario in more detail and to construct specific models. After reviewing the simple symmetry structure that underpins all baryon-symmetric models, we turn to a detailed analysis of the required Affleck-Dine dynamics. Both gravity-mediated and gauge-mediated supersymmetry breaking are considered, with the messenger scale left arbitrary in the latter, and the viable regions of parameter space are determined. In the gauge-mediated case where gravitinos are light and stable, the regime where they constitute a small fraction of the dark matter density is identified. We discuss the formation of Q-balls, and delineate various regimes in the parameter space of the Affleck-Dine potential with respect to their stability or lifetime and their decay modes. We outline the regions in which Q-ball formation and decay is consistent with successful pangenesis. Examples of viable dark sectors are presented, and constraints are derived from big bang nucleosynthesis, large scale structure formation and the Bullet cluster. Collider signatures and implications for direct dark matter detection experiments are briefly discussed. The following would constitute evidence for pangenesis: supersymmetry, GeV-scale dark matter mass(es) and a Z' boson with a significant invisible width into the dark sector.Comment: 51 pages, 7 figures; v2: minor modifications, comments and references added; v3: minor changes, matches published versio

The Effect of the Short-Range Correlations on the Generalized Momentum Distribution in Finite Nuclei

The effect of dynamical short-range correlations on the generalized momentum distribution $n(\vec{p},\vec{Q})$ in the case of $Z=N$, $\ell$-closed shell nuclei is investigated by introducing Jastrow-type correlations in the harmonic-oscillator model. First, a low order approximation is considered and applied to the nucleus $^4$He. Compact analytical expressions are derived and numerical results are presented and the effect of center-of-mass corrections is estimated. Next, an approximation is proposed for $n(\vec{p}, \vec{Q})$ of heavier nuclei, that uses the above correlated $n(\vec{p},\vec{Q})$ of $^4$He. Results are presented for the nucleus $^{16}$O. It is found that the effect of short-range correlations is significant for rather large values of the momenta $p$ and/or $Q$ and should be included, along with center of mass corrections for light nuclei, in a reliable evaluation of $n(\vec{p},\vec{Q})$ in the whole domain of $p$ and $Q$.Comment: 29 pages, 8 figures. Further results, figures and discussion for the CM corrections are added. Accepted by Journal of Physics

Freeze-In Production of FIMP Dark Matter

We propose an alternate, calculable mechanism of dark matter genesis, "thermal freeze-in," involving a Feebly Interacting Massive Particle (FIMP) interacting so feebly with the thermal bath that it never attains thermal equilibrium. As with the conventional "thermal freeze-out" production mechanism, the relic abundance reflects a combination of initial thermal distributions together with particle masses and couplings that can be measured in the laboratory or astrophysically. The freeze-in yield is IR dominated by low temperatures near the FIMP mass and is independent of unknown UV physics, such as the reheat temperature after inflation. Moduli and modulinos of string theory compactifications that receive mass from weak-scale supersymmetry breaking provide implementations of the freeze-in mechanism, as do models that employ Dirac neutrino masses or GUT-scale-suppressed interactions. Experimental signals of freeze-in and FIMPs can be spectacular, including the production of new metastable coloured or charged particles at the LHC as well as the alteration of big bang nucleosynthesis.Comment: 30 pages, 7 figures, PDFLaTex. References adde

Renal cell carcinoma metastasizing to solitary fibrous tumor of the pleura: a case report

<p>Abstract</p> <p>Introduction</p> <p>A tumor metastasizing to another malignancy is an uncommon phenomenon. Since it was first described in 1902, there have been fewer than 200 cases reported in the literature, with lung cancer metastasizing to renal cell carcinoma being the most frequently described pattern. Here we report a case of a solitary fibrous tumor of the lung acting as the recipient for a renal cell carcinoma. To our knowledge, this is the first reported case of such a combination and the second case involving a solitary fibrous tumor.</p> <p>Case presentation</p> <p>A 58-year-old Caucasian man who developed a persistent dry cough presented to our hospital. Imaging studies revealed a large pleural-based mass in the left lung. A biopsy of the mass showed a spindle-cell lesion consistent with a solitary fibrous tumor. The patient underwent surgical excision of the 13 cm mass. The pathological examination confirmed the diagnosis of a solitary fibrous tumor but also demonstrated discrete foci of metastatic renal cell carcinoma. Until that point, a primary renal cell carcinoma tissue diagnosis had not been made and the initial radiological work-up was inconclusive.</p> <p>Conclusion</p> <p>Awareness of the unusual phenomenon of tumor-to-tumor metastasis is important for practicing surgical pathologists, particularly in the evaluation of a mass lesion showing bimodal histology. This case also highlights the importance of careful examination of surgical specimens, as minute and unusual findings can direct patient care.</p

Asymmetric Dark Matter and Dark Radiation

Asymmetric Dark Matter (ADM) models invoke a particle-antiparticle asymmetry, similar to the one observed in the Baryon sector, to account for the Dark Matter (DM) abundance. Both asymmetries are usually generated by the same mechanism and generally related, thus predicting DM masses around 5 GeV in order to obtain the correct density. The main challenge for successful models is to ensure efficient annihilation of the thermally produced symmetric component of such a light DM candidate without violating constraints from collider or direct searches. A common way to overcome this involves a light mediator, into which DM can efficiently annihilate and which subsequently decays into Standard Model particles. Here we explore the scenario where the light mediator decays instead into lighter degrees of freedom in the dark sector that act as radiation in the early Universe. While this assumption makes indirect DM searches challenging, it leads to signals of extra radiation at BBN and CMB. Under certain conditions, precise measurements of the number of relativistic species, such as those expected from the Planck satellite, can provide information on the structure of the dark sector. We also discuss the constraints of the interactions between DM and Dark Radiation from their imprint in the matter power spectrum.Comment: 22 pages, 5 figures, to be published in JCAP, minor changes to match version to be publishe

KeV Warm Dark Matter and Composite Neutrinos

Elementary keV sterile Dirac neutrinos can be a natural ingredient of the composite neutrino scenario. For a certain class of composite neutrino theories, these sterile neutrinos naturally have the appropriate mixing angles to be resonantly produced warm dark matter (WDM). Alternatively, we show these sterile neutrinos can be WDM produced by an entropy-diluted thermal freeze-out, with the necessary entropy production arising not from an out-of-equilibrium decay, but rather from the confinement of the composite neutrino sector, provided there is sufficient supercooling.Comment: 12 pages, 2 figures, published versio