Supernova bound on keV-mass sterile neutrinos reexamined

Active-sterile neutrino mixing is strongly constrained for m_s > 100 keV to avoid excessive energy losses from supernova cores. For smaller m_s, matter effects suppress the effective mixing angle except for a resonant range of energies where it is enhanced. We study the case of \nu_tau-\nu_s-mixing where a \nu_tau-\bar\nu_tau asymmetry builds up due to the strong excess of \nu_s over \bar\nu_s emission or vice versa, reducing the overall emission rate. In the warm dark matter range m_s < 10 keV the mixing angle is essentially unconstrained.Comment: 6 pages, 4 figures; minor changes, references updated, matches the published versio

Vulnerability to pine sawfly damage decreases with site fertility but the opposite is true with Scleroderris canker damage; results from Finnish ICP Forests and NFI data

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Late gestation diet supplementation of resin acid-enriched composition increases sow colostrum immunoglobulin G content, piglet colostrum intake and improve sow gut microbiota

Resin acid-enriched composition (RAC) mainly containing tall oil fatty acid with an active component of resin acid (RA) can improve the microbial population in the digestive system, change the microbial fermentation, and improve the feed conversion ratio. We investigated the effects of dietary supplementation of RAC on sow colostrum yield (CY), colostrum composition and gut microbiota. Tall oil fatty acid and RA are commonly termed RAC and CLA, pinolenic, abietic, dehydrobiotic acids are characteristic components of RAC. The experiment was conducted in three trials in three respective herds. Sows were fed with a control diet and the same diet supplemented with 5 g RAC/day per sow during the last week of gestation. The 16S ribosomal RNA gene sequencing technique was used to assess sows' faecal microbiota populations at farrowing. Colostrum nutritional composition, acute phase proteins (APPs) and immunoglobulin (Ig) content were also assessed. Individual piglets were weighed at birth and 24 h after the birth of first piglets in order to calculate CY and later at 3 to 4 weeks to calculate average daily gain. The RAC-fed sows had significantly higher IgG levels (P0.05), but those fed RAC had higher levels of colostrum serum amyloid A. Colostrum yield was significantly higher in RAC-fed sows in herds 2 and 3 with heavier piglets between 3 and 4 weeks of age (P0.05). Resin acid-enriched composition supplementation significantly increased some beneficial and fermentative bacteria (Romboutsia and Clostridium sensu stricto) than the control diet (PPeer reviewe

Avoiding BBN Constraints on Mirror Models for Sterile Neutrinos

We point out that in models that explain the LSND result for neutrino oscillation using the mirror neutrinos, the big bang nucleosynthesis constraint can be avoided by using the late time phase transition that only helps to mix the active and the sterile neutrinos. We discuss the astrophysical as well as cosmological implications of this proposal.Comment: 5 pages, latex; more discussion added; results unchange

Light Unstable Sterile Neutrino

The three massless active (doublet) neutrinos may mix with two heavy and one \underline {light} sterile (singlet) neutrinos so that the induced masses and mixings among the former are able to explain the present data on atmospheric and solar neutrino oscillations. If the LSND result is also to be explained, one active neutrino mass eigenstate must mix with the light sterile neutrino. A specific model is proposed with the spontaneous and soft explicit breaking of a new global $U(1)_S$ symmetry so that a sterile neutrino will decay into an active antineutrino and a nearly massless pseudo-Majoron.Comment: Discussion and references adde

Administration of aromatase inhibitor MPV-2213ad to blue fox vixens (Vulpes lagopus) as a model for contraception in female dogs

The interest in non-surgical approaches to contraception and fertility control in female dogs has increased in recent years. In this study the effect of an aromatase inhibitor (finrozole) was evaluated in fur production animals, farmed blue fox vixens, as a model for contraception in bitches. A total of 80 vixens were divided into 4 groups, receiving orally placebo (A) or finrozole 0.5 mg/kg (B), 3.5 mg/kg (C) or 24.5 mg/kg (D) for 21 consecutive days beginning in the pre-ovulatory period of heat. Monitoring of the vixens included clinical signs of heat, measurement of vaginal electrical resistance (VER) as well as oestradiol and progesterone concentrations in plasma. The approximate relation of the start of treatment to ovulation varied from 11 days before to one day after ovulation provided that the LH peak occurred 0.5 -2 days before the VER peak and ovulation was then estimated to occur 2 days after the LH peak. Seventy vixens were artificially inseminated within 8 h after a 50 Omega decline in vaginal electrical resistance was detected. Ten vixens were not inseminated. Pregnancy was confirmed by transabdominal ultrasound examination and birth of cubs was recorded. The pregnancy rates in the groups were 89.5% (A), 81.3% (B), 55.6% (C) and 52.9% (D). The average number of live born pups in the four groups was 9.4 (A), 7.0 (B), 5.8 (C), and 3.8 (D), respectively. No deleterious effects (for instance malformations) of finrozole on pups could be verified. The administration of finrozole did not have a significant effect on oestradiol parameters and VER values in vixens. Progesterone values were significantly higher in treatment groups compared with the placebo group. The results indicate that pregnancy could be avoided by finrozole provided that doses of >= 3.5 mg/kg were used and the treatment was initiated at least four days before the day of artificial insemination. This corresponds with two to six days before ovulation provided that the LH peak occurred 0.5-2 days before the VER peak and that ovulation then occurred in average 2 days after the LH peak. (C) 2020 The Authors. Published by Elsevier Inc.Peer reviewe

Neutrino Mass Texture with Large Mixing

We propose a simple texture for the right-handed Majorana mass matrix to give a large $\nu_\mu-\nu_\tau$ mixing angle and hierarchical left-handed neutrino mass pattern. Consistently with the Dirac mass texture of the quark sector realizing the CKM mixing, this naturally explains the recent experimental results on both the atmospheric neutrino anomaly observed by the Superkamiokande collaboration and the solar neutrino problem. In this texture the right-handed Majorana mass of the third generation is of the order of GUT scale, which is favorable for reproducing the observed bottom-tau mass ratio.Comment: 10 pages, LaTeX, comments and references adde

Measurements of muon flux in the Pyh\"asalmi underground laboratory

The cosmic-ray induced muon flux was measured at several depths in the Pyh\"asalmi mine (Finland) using a plastic scintillator telescope mounted on a trailer. The flux was determined at four different depths underground at 400 m (980 m.w.e), at 660 m (1900 m.w.e), at 990 m (2810 m.w.e) and at 1390 m (3960 m.w.e) with the trailer, and also at the ground surface. In addition, previously measured fluxes from depths of 90 m (210 m.w.e) and 210 m (420 m.w.e) are shown. A relation was obtained for the underground muon flux as a function of the depth. The measured flux follows well the general behaviour and is consistent with results determined in other underground laboratories.Comment: 8 pages, 2 figures. Submitted to Nuclear Instrum. Methods

Transition to adult care in Finnish adolescents with juvenile idiopathic arthritis

Objective The symptoms of juvenile idiopathic arthritis (JIA) and the necessity for continuous treatment may persist in adulthood. Therefore, patients with JIA need to be appropriately transferred to adult care. We aimed to analyse the timing of the patients' transition to adult care, and patients' self-management skills with the process and the quality of the transition. Method This study included 161 Finnish participants of the population-based Nordic JIA cohort who attended a 17 year follow-up appointment. Special attention was paid to the three groups: those referred by the paediatric rheumatology outpatient clinic to primary healthcare (PHC), those who were directly transferred to adult rheumatology care, and those who were later referred. Results A total of 136 patients (84%) were eligible to participate in the study, and 40% of them were directly transferred to an adult rheumatology clinic. Of the patients, 72% eventually ended up being referred to an adult rheumatology outpatient clinic. However, 16% of the patients in the PHC group had active disease during the study appointment and were referred to adult services after the study visit. Conclusion This study reveals the need to improve the transition process from paediatric care to adult care and to find the variables that can indicate the need for immediate transition. Although challenging, it is important to avoid treatment delay in adult patients with JIA who may have active disease but who do not have appropriate access to an adult rheumatological outpatient clinic.Peer reviewe

Neutrino Anomalies and Quasi-Dirac neutrinos

We discuss possibility of describing solar, atmospheric and LSND results with four neutrinos forming two quasi-degenerate pairs. The simplest versions of this 2+2 scheme with either $\nu_e$ or $\nu_\mu$ mixing exclusively with sterile neutrino is disfavored by the SNO and atmospheric neutrino results respectively. A generalized scheme with sterile state participating in both the solar and atmospheric oscillations is still allowed. We show thasolar and atmospheric oscillations is still allowed. We show that the complex pattern of mixing needed for this purpose follows from a simple L_e+L_\mu-L_\tau-L_s symmetry. Specific form of L_e+L_\mu-L_\tau-L_s symmetric mass matrix is determined from experimental results. Two theoretical schemes which lead to this form and a proper breaking of L_e+L_\mu-L_\tau-L_s symmetry are discussed.Comment: 15 pages, LATEX, minor corrections; addition of few reference