981 research outputs found

    Comparative study of potato cultivation through micropropagation and conventional farming methods

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    A trial was carried out to evaluate the productivity of Solanum tuberosum L. cultivated through conventional farming and micropropagation method. Survival rate, biomass and tuber yield of both micropropagated and tuber propagated potatoes was evaluated. Survival percentages of potatoes were 90% for conventional propagation and 85% for micropropagation. The survival rate of micropropagated plants were maximum of 79% in vermicompost and minimum of 50% in the soil. The average shoot length, number of leaves and leaf area was greater in tuber propagated plants compared to the micropropagated plants. Tuber propagated plants yielded 1.360 kg/plant which was 0.370 kg/plant more than micropropagated plant.Keywords: Conventional farming, micropropagation, potatoes, tuber propagatio

    Quantum cohomology via vicious and osculating walkers

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    We relate the counting of rational curves intersecting Schubert varieties of the Grassmannian to the counting of certain non-intersecting lattice paths on the cylinder, so-called vicious and osculating walkers. These lattice paths form exactly solvable statistical mechanics models and are obtained from solutions to the Yang–Baxter equation. The eigenvectors of the transfer matrices of these models yield the idempotents of the Verlinde algebra of the gauged u^(n)k -WZNW model. The latter is known to be closely related to the small quantum cohomology ring of the Grassmannian. We establish further that the partition functions of the vicious and osculating walker model are given in terms of Postnikov’s toric Schur functions and can be interpreted as generating functions for Gromov–Witten invariants. We reveal an underlying quantum group structure in terms of Yang–Baxter algebras and use it to give a generating formula for toric Schur functions in terms of divided difference operators which appear in known representations of the nil-Hecke algebra

    Decomposable representations and Lagrangian submanifolds of moduli spaces associated to surface groups

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    In this paper, we construct a Lagrangian submanifold of the moduli space associated to the fundamental group of a punctured Riemann surface (the space of representations of this fundamental group into a compact connected Lie group). This Lagrangian submanifold is obtained as the fixed-point set of an anti-symplectic involution defined on the moduli space. The notion of decomposable representation provides a geometric interpretation of this Lagrangian submanifold

    Time and causes of submergence of ancient temple structures off Mahabalipuram, East Coast of India

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    658-665As per traditional belief, some part of the ancient town of Mahabalipuram had been submerged just off the shore temple and this story has been recorded by the several British travelers during the 18th – 19th century. During the underwater exploration of Mahabalipuram area in 2017, three sites along with a large number of scattered dressed stones were found in the intertidal zone. Calcareous material grown over these stone structures after their submergence in seawater was subjected to radiocarbon (14C) dating to infer submergence time-periods of these structures. Submergence date for the site I is the late 14th century CE; whereas the submergence date from the site II comes ~ 1st century CE. According to the water-depths from where the studied structural remains were excavated, and obtained 14C dates of submergence, it could be surmised that these stone-structures off Mahabalipuram town were submerged in two phases. The submergence might have been induced by natural events such as coastal cyclone activity or Tsunami that flushed off sand around these structures and raised the sealevels locally over the coast

    Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G protein-coupled receptors

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    Agonist stimulation of G protein-coupled receptors (GPCRs) typically leads to phosphorylation of GPCRs and binding to multifunctional proteins called β-arrestins (βarrs). The GPCR-βarr interaction critically contributes to GPCR desensitization, endocytosis, and downstream signaling, and GPCR-βarr complex formation can be used as a generic readout of GPCR and βarr activation. Although several methods are currently available to monitor GPCR-βarr interactions, additional sensors to visualize them may expand the toolbox and complement existing methods. We have previously described antibody fragments (FABs) that recognize activated βarr1 upon its interaction with the vasopressin V2 receptor C-terminal phosphopeptide (V2Rpp). Here, we demonstrate that these FABs efficiently report the formation of a GPCR-βarr1 complex for a broad set of chimeric GPCRs harboring the V2R C terminus. We adapted these FABs to an intrabody format by converting them to single-chain variable fragments (ScFvs) and used them to monitor the localization and trafficking of βarr1 in live cells. We observed that upon agonist simulation of cells expressing chimeric GPCRs, these intrabodies first translocate to the cell surface, followed by trafficking into intracellular vesicles. The translocation pattern of intrabodies mirrored that of βarr1, and the intrabodies co-localized with βarr1 at the cell surface and in intracellular vesicles. Interestingly, we discovered that intrabody sensors can also report βarr1 recruitment and trafficking for several unmodified GPCRs. Our characterization of intrabody sensors for βarr1 recruitment and trafficking expands currently available approaches to visualize GPCR-βarr1 binding, which may help decipher additional aspects of GPCR signaling and regulation

    Structure-Activity Relationships in Toll-like Receptor 2-Agonists Leading to Simplified Monoacyl Lipopeptides

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    Toll-like receptor 2-agonistic lipopeptides typified by S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-R-cysteinyl-S-serine (PAM2CS) compounds are potential vaccine adjuvants. In continuation of previously reported structure-activity relationships on this chemotype, we have determined that at least one acyl group of optimal length (C16) and an appropriately orientated ester carbonyl group is essential for TLR2-agonistic activity. The spacing between one of the palmitoyl ester carbonyl and the thioether is crucial to allow for an important H-bond, which observed in the crystal structure of the lipopeptide:TLR2 complex; consequently, activity is lost in homologated compounds. Penicillamine-derived analogues are also inactive, likely due to unfavorable steric interactions with the carbonyl of Ser 12 in TLR2. The thioether in this chemotype can be replaced with a selenoether. Importantly, the thioglycerol motif can be dispensed with altogether, and can be replaced with a thioethanol bridge. These results have led to a structurally simpler, synthetically more accessible, and water-soluble analogue possessing strong TLR2-agonistic activities in human blood

    Porosity of closed carbon nanotubes compressed using hydraulic pressure

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    Experimental data of nitrogen adsorption (T = 77.3 K) from gaseous phase measured on commercial closed carbon nanotubes are presented. Additionally, we show the results of N2 adsorption on compressed (using hydraulic press) CNTs. In order to explain the experimental observations the results of GCMC simulations of N2 adsorption on isolated or bundled multi-walled closed nanotubes (four models of bundles) are discussed. We show that the changes of the experimental adsorption isotherms are related to the compression of the investigated adsorbents. They are qualitatively similar to the theoretical observations. Taking into account all results it is concluded that in the "architecture" of nanotubes very important role has been played by isolated nanotubes

    Evidences for a quasi 60-year North Atlantic Oscillation since 1700 and its meaning for global climate change

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    The North Atlantic Oscillation (NAO) obtained using instrumental and documentary proxy predictors from Eurasia is found to be characterized by a quasi 60-year dominant oscillation since 1650. This pattern emerges clearly once the NAO record is time integrated to stress its comparison with the temperature record. The integrated NAO (INAO) is found to well correlate with the length of the day (since 1650) and the global surface sea temperature record HadSST2 and HadSST3 (since 1850). These findings suggest that INAO can be used as a good proxy for global climate change, and that a 60-year cycle exists in the global climate since at least 1700. Finally, the INAO ~60-year oscillation well correlates with the ~60- year oscillations found in the historical European aurora record since 1700, which suggests that this 60-year dominant climatic cycle has a solar-astronomical origin

    Systematics of Inclusive Photon Production in 158 AGeV Pb Induced Reactions on Ni, Nb, and Pb Targets

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    The multiplicity of inclusive photons has been measured on an event-by-event basis for 158 AGeV Pb induced reactions on Ni, Nb, and Pb targets. The systematics of the pseudorapidity densities at midrapidity (rho_max) and the width of the pseudorapidity distributions have been studied for varying centralities for these collisions. A power law fit to the photon yield as a function of the number of participating nucleons gives a value of 1.13+-0.03 for the exponent. The mean transverse momentum, , of photons determined from the ratio of the measured electromagnetic transverse energy and photon multiplicity, remains almost constant with increasing rho_max. Results are compared with model predictions.Comment: 16 pages including 4 figure
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