FIGO best practice guidance in surgical consent

Obtaining medical consent preoperatively is one of the key steps in preparing for surgery, and is an important step in informed decision making with the patient. According to good medical practice guidelines, doctors are required to have the knowledge and skills to treat patients as well as inform them, respect their wishes, and establish trust between themselves and their patients. Valid consent includes elements of competence, disclosure, understanding, and voluntariness. Documentation of these elements is also very important. The International Federation of Gynecology and Obstetrics (FIGO) Education Communication and Advocacy Consortium (ECAC) has realized that the quality of consent varies considerably across the world and has developed simple guidelines regarding consent and procedure-specific checklists for the most common obstetric and gynecological procedures

IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation

The single nucleotide polymorphism rs55705857, located in a non-coding but evolutionarily conserved region at 8q24.21, is strongly associated with IDH-mutant glioma development and was suggested to be a causal variant. However, the molecular mechanism underlying this association has remained unknown. With a case control study in 285 gliomas, 316 healthy controls, 380 systemic cancers, 31 other CNS-tumors, and 120 IDH-mutant cartilaginous tumors, we identified that the association was specific to IDH-mutant gliomas. Odds-ratios were 9.25 (5.17–16.52; 95% CI) for IDH-mutated gliomas and 12.85 (5.94–27.83; 95% CI) for IDH-mutated, 1p/19q co-deleted gliomas. Decreasing strength with increasing anaplasia implied a modulatory effect. No somatic mutations were noted at this locus in 114 blood-tumor pairs, nor was there a copy number difference between risk-allele and only-ancestral allele carriers. CCDC26 RNA-expression was rare and not different between the two groups. There were only minor subtype-specific differences in common glioma driver genes. RNA sequencing and LC-MS/MS comparisons pointed to significantly altered MYC-signaling. Baseline enhancer activity of the conserved region specifically on the MYC promoter and its further positive modulation by the SNP risk-allele was shown in vitro. Our findings implicate MYC deregulation as the underlying cause of the observed association

TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX

Introduction: In many health conditions, stigma is receiving increasing attention. Public stigmatization toward social illness can affect particularly the patients and family memberships to help seeking behavior and treatment. This study, the aim of this study was to investigate the validity and reliability of the Turkish Stigma of Tuberculosis Scale which was developed to evaluate of perception of stigma with tuberkulosis patient. Patients and Methods: This methodological study was conducted with 150 with tuberculosis disease people who above 18 age and without known psychological and mental disability. In the study, Stigma of Tuberculosis Scale was used as data collection tool. During the study, language equivalence, content validity, reliability and construct validity of the scale was performed. The data was assessed by using mean, median, standard deviation, Spearman Correlation, Cronbach Alpha coefficient and confirmatory factor analysis. Results: The mean age of study participants was 45.6 +/- 16.1 ( 20 - 85). years. Spearman correlation coefficient of the scale for test-retest reliability was 0.853 and the Cronbach Alpha coefficient was 0.95. According to fit indexes of confirmatory factor analysis [x2/SD= 481.38/230= 2.09; RMSEA= 0.087; GFI= 0.776; CFI= 0.776; NNFI= 0.875] it was found that one factors were appropriate for the scale. Conclusion: The adoption of the translated Stigma of Tuberculosis Scale in Turkey is found reliable and valid to evaluate of perception of stigma with tuberkulosis patient

AUSTRALIAN JOURNAL OF PRIMARY HEALTH

Domestic violence against women is an important social and public health problem worldwide resulting from unequal power relationships between men and women. The purpose of the present cross-sectional descriptive study was to determine the factors affecting the views and experiences of women living in the city centre of Manisa, Turkey, regarding domestic violence. The data were collected from a representative sample of women (n=873) in 2012. The socio-demographic questionnaire and the World Health Organization's Multi-country Study on Women's Health and Domestic Violence Against Women were used for data collection. The study results revealed that of the women, 14.8% were exposed to physical violence, 7.9% to sexual violence, 20.2% to emotional violence/abuse and 11.2% to economic violence/abuse within the last 12 months. Lower income level, lower social status, lower educational level, unemployment, being exposed to parental violence during childhood and being married to husbands exposed to parental violence during childhood were associated risk factors with domestic violence. The study results indicate that domestic violence against women is a common phenomenon in Manisa

Effects of tillage, ridging and row spacing on seedling emergence and yield of cotton

Field experiments were conducted at Harran Plain on a clay silt soil (Xerosol in FAO/UNESCO soil classification) in Southeast of Turkey in 1996 and 1997 to study the effects of cotton planting system, tillage method, and row spacing on the performances of cotton (Gossypium hirsutum L.), such as seedling emergence and yield. The tillage methods evaluated were: traditional (inversion) with a mouldboard plough (M) and conservation (non-inversion) with chisel tine (C). The seedbeds studied were: normal planting system (NS) with no-ridging, and ridge planting system (RS). Results showed that mouldboard plough had slightly greater yield than chisel in each year but the difference was not significance in 1997. Non-ridging had the second best emergence rate and yield according to 2 years mean. Ridging with chisel in 70cm row spacing produced the highest seedling emergence for both years, but the difference was not significance in 1997. The yields obtained for ridging with mouldboard plough from 70cm row spacing in 1996, and for ridging with mouldboard plough from 76cm in 1997 were superior to the other applications. Finally 70cm row spacing produced the highest seedling emergence and yield in both years regardless of the treatment. Row spacing of 90cm resulted in the lowest seedling emergence and yield in both years regardless of the treatment. The results indicate that ridging can be used instead of non-ridging with 76cm row spacing (suitable for mechanical harvesting) which gave similar yield to the ridging with 70cm row spacing in 1997, and both of the planting systems with 76cm seem to be suitable to mechanical harvesting. © 2003 Elsevier B.V. All rights reserved

Dose-dependent effects of specific egg-yolk antibodies on diarrhea of newborn calves

In a field trial on a farm in Turkey, we tested whether specific egg-yolk antibodies had a prophylactic effect on neonatal diarrhea. Owing to its antibody spectrum, this egg powder was very suitable for this farm since mainly rotavirus was identified, Regardless of the dosage (2 g, 4 g, or 8 g egg powder), the calves(n = 164) which received specific egg-yolk antibodies via the whole egg during the first 14 days of life showed significant improvements in risk and duration of diarrhea and in body weight gain compared with calves of the control group (n = 80) which had not received any egg powder, These significant differences in body weight still persisted after 3 months of life, The mortality risk in the control group amounted to 8.8%, while in all egg powder groups (n = 164) only one calf died as a result of diarrhea, Breed-dependent differences in the parameters were not observed

Comparisons of serum somatotropin, 3,5,3 '-triiodothyronine, thyroxine, total protein and free fatty acid levels in newborn Sakiz lambs separated from or suckling their dams

Objective: To determine the effects on serum somatotropin, 3,5,3'-triiodothyronine (T-3), thyroxine (T-4), free fatty acids (FFAs) and total protein levels of different feedings and age in Sakiz sheep that have a high twin-bearing rate supported by estrous synchronization. Methods: 20 newborn lambs were used in the study. Lambs were divided into 2 equal groups. The lambs in 1 group were separated from their dams following parturition, and those in other group were kept together with their dams. Separated lambs were fed commercial cow's milk for 2.5 weeks. After that, they were fed a milk substitute, hay and concentrated supplement for 2 months, and from the end of the 2 months they were fed hay and concentrated supplement. The lambs in other group were kept together with their dams only during the day and in addition were fed hay and concentrated supplement. After 2 months, they were maintained feeding only on hay and concentrated supplement. Blood samples were taken from vena jugularis of lambs at 12 and 24-48 h, and 14, 28, 42 and 56-90 days after parturition. Serum samples were analyzed for somatotropin by enzyme immunoassay, for T-3 and T-4 by radioimmunoassay, and for total protein and FFA by a spectrophotometric method. Results: Serum somatotropin levels were insignificantly different between the lambs with and without their dams. Serum T-3 levels were generally lower in the separated lambs than those in other group. Serum T-4 levels were significantly lower in the separated lambs 48 h and 90 days after parturition than those in other group. Serum FFAs were insignificantly different between 2 groups. Serum total protein concentrations were lower in the separated lambs than lambs kept together with their dams (significantly at 12 and 48 h and 14 days). Conclusion: Ingestion of colostrum and dam milk markedly affected serum total protein levels, but body weight and serum somatotropin levels were insignificantly affected. Also serum T-3 and T-4 levels markedly decreased with advancing age. Serum FFA levels were not affected by the trial. Copyright (C) 2005 S. Karger AG, Basel