Probing the Intergalactic Medium with Fast Radio Bursts

The recently discovered fast radio bursts (FRBs), presumably of extra-galactic origin, have the potential to become a powerful probe of the intergalactic medium (IGM). We point out a few such potential applications. We provide expressions for the dispersion measure and rotation measure as a function of redshift, and we discuss the sensitivity of these measures to the HeII reionization and the IGM magnetic field. Finally we calculate the microlensing effect from an isolate, extragalctic stellar-mass compact object on the FRB spectrum. The time delays between the two lensing images will induce constructive and destructive interference, leaving a specific imprint on the spectra of FRBs. With a high all-sky rate, a large statistical sample of FRBs is expected to make these applications feasible.Comment: 4 pages, 1 figure; Typos for the variable x in Eq.6 corrected; Published in ApJ; Originally the Appendix E of arXiv:1402.4766; Separated from the main paper upon the referee's reques

The bb quark fragmentation fractions at LHCb and meson decays with heavy quark spectators

We study the current estimates of $B_c\to B_s \pi$ to extract the fragmentation fraction $f_c/f_s$ at the LHCb. A rather robust estimate of $Br(B_c\to B_s \pi)$ based on factorization and lattice results for the form factor gives $f_c/f_s \sim 0.056$ with a $16\%$ error. We also revisit the extraction of $f_s/f_d$ using $B\to D\pi$ instead of the theoretical cleaner but more suppressed channel $B\to DK$. We also find a tension on the predictions of $Br(B_c\to J/\psi \pi)$ and $Br(B_c\to B_s\pi)$ considering the measurements of these modes at LHCb, and find that, within a $23\%$ uncertainty, only the lower end of the current prediction range $Br(B_c\to J/\psi)\sim 0.4\% - 1.7\%$ would be consistent with the LHCb measurements.Comment: 11 pages, 2 figure

A comparative study of the schizontocidal efficacy and safety of artemether versus chloroquine in uncomplicated malaria

A comparative study of medications being used for malaria treatment in Zimbabwe

Search for sterile neutrinos decaying into pions at the LHC

We study the possibility to observe sterile neutrinos with masses in the range between 5 GeV and 20 GeV at the LHC, using the exclusive semileptonic modes involving pions, namely W to lepton + N to n pions + lepton+lepton (n = 1, 2, 3). The two pion and three pion modes require extrapolations of form factors to large time-like $q^2$, which we do using vector dominance models as well as light front holographic QCD, with remarkable agreement. This mass region is difficult to explore with inclusive dilepton+dijet modes or trilepton modes and impossible to explore in rare meson decays. While particle identification is a real challenge in these modes, vertex displacement due to the long living neutrino in the above mass range can greatly help reduce backgrounds. Assuming a sample of $10^9$ W bosons at the end of the LHC Run 2, these modes could discover a sterile neutrino in the above mass range or improve the current bounds on the heavy-to-light lepton mixings by an order of magnitude, $U_{l N}^2 \sim 2 \times 10^{-6}$. Moreover, by studying the equal sign and opposite sign dileptons, the Majorana or Dirac character of the sterile neutrino may be revealed.Comment: 18 pages, 4 double figure

Precision Pointing of IBEX-Lo Observations

Post-launch boresight of the IBEX-Lo instrument onboard the Interstellar Boundary Explorer (IBEX) is determined based on IBEX-Lo Star Sensor observations. Accurate information on the boresight of the neutral gas camera is essential for precise determination of interstellar gas flow parameters. Utilizing spin-phase information from the spacecraft attitude control system (ACS), positions of stars observed by the Star Sensor during two years of IBEX measurements were analyzed and compared with positions obtained from a star catalog. No statistically significant differences were observed beyond those expected from the pre-launch uncertainty in the Star Sensor mounting. Based on the star observations and their positions in the spacecraft reference system, pointing of the IBEX satellite spin axis was determined and compared with the pointing obtained from the ACS. Again, no statistically significant deviations were observed. We conclude that no systematic correction for boresight geometry is needed in the analysis of IBEX-Lo observations to determine neutral interstellar gas flow properties. A stack-up of uncertainties in attitude knowledge shows that the instantaneous IBEX-Lo pointing is determined to within \sim 0.1\degr in both spin angle and elevation using either the Star Sensor or the ACS. Further, the Star Sensor can be used to independently determine the spacecraft spin axis. Thus, Star Sensor data can be used reliably to correct the spin phase when the Star Tracker (used by the ACS) is disabled by bright objects in its field-of-view. The Star Sensor can also determine the spin axis during most orbits and thus provides redundancy for the Star Tracker.Comment: 22 pages, 18 figure

Comet assay to measure DNA repair: approach and applications

Cellular repair enzymes remove virtually all DNA damage before it is fixed; repair therefore plays a crucial role in preventing cancer. Repair studied at the level of transcription correlates poorly with enzyme activity, and so assays of phenotype are needed. In a biochemical approach, substrate nucleoids containing specific DNA lesions are incubated with cell extract; repair enzymes in the extract induce breaks at damage sites and the breaks are measured with the comet assay. The nature of the substrate lesions defines the repair pathway to be studied. This in vitro DNA repair assay has been modified for use in animal tissues, specifically to study the effects of aging and nutritional intervention on repair. Recently, the assay was applied to different strains of Drosophila melanogaster proficient and deficient in DNA repair. Most applications of the repair assay have been in human biomonitoring. Individual DNA repair activity may be a marker of cancer susceptibility; alternatively, high repair activity may result from induction of repair enzymes by exposure to DNA-damaging agents. Studies to date have examined effects of environment, nutrition, lifestyle and occupation, in addition to clinical investigations

Concerted changes in tropical forest structure and dynamics: evidence from 50 South American long-term plots

Several widespread changes in the ecology of old-growth tropical forests have recently been documented for the late twentieth century, in particular an increase in stem turnover (pan-tropical), and an increase in above-ground biomass (neotropical). Whether these changes are synchronous and whether changes in growth are also occurring is not known. We analysed stand-level changes within 50 long-term. monitoring plots from across South America spanning 1971-2002. We show that: (i) basal area (BA: sum of the cross-sectional areas of all trees in a plot) increased significantly over time (by 0.10 +/- 0.04 m(2) ha(-1) yr(-1), mean +/- 95% CI); as did both (ii) stand-level BA growth rates (sum of the increments of BA of surviving trees and BA of new trees that recruited into a plot); and (iii) stand-level BA mortality rates (sum of the cross-sectional areas of all trees that died in a plot). Similar patterns were observed on a per-stem basis: (i) stem density (number of stems per hectare; 1 hectare is 10(4) m(2)) increased significantly over time (0.94 +/- 0.63 stems ha(-1) yr(-1)); as did both (ii) stem recruitment rates; and (iii) stem mortality rates. In relative terms, the pools of BA and stem density increased by 0.38 +/- 0.15% and 0.18 +/- 0.12% yr(-1), respectively. The fluxes into and out of these pools-stand-level BA growth, stand-level BA mortality, stem recruitment and stem mortality rates-increased, in relative terms, by an order of magnitude more. The gain terms (BA growth, stem recruitment) consistently exceeded the loss terms (BA loss, stem mortality) throughout the period, suggesting that whatever process is driving these changes was already acting before the plot network was established. Large long-term increases in stand-level BA growth and simultaneous increases in stand BA and stem density imply a continent-wide increase in resource availability which is increasing net primary productivity and altering forest dynamics. Continent-wide changes in incoming solar radiation, and increases in atmospheric concentrations of CO2 and air temperatures may have increased resource supply over recent decades, thus causing accelerated growth and increased dynamism across the world's largest tract of tropical forest