1,352 research outputs found

    Taxation

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    Assessment of on-farm, market and wild food diversity in three agro-ecological zones of Western Kenya

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    Poster presented at Tropentag 2014. International Conference on Research on Food Security, Natural Resource Management and Rural Development. "Bridging the Gap between Increasing Knowledge and Decreasing Resources" Prague (Czech Republic) Sep 17-19 2014

    Laser-assisted solar cell metallization processing

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    Laser-assisted processing techniques for producing high-quality solar cell metallization patterns are being investigated, developed, and characterized. The tasks comprising these investigations are outlined

    Fruit consumption and production: habits, preferences and attitudes of rural households in Western Kenya

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    Senior Programmers: Characteristics of Elderly Users from Stack Overflow

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    In this paper we presents results of research about elderly users of Stack Overflow (Question and Answer portal for programmers). They have different roles, different main activities and different habits. They are an important part of the community, as they tend to have higher reputation and they like to share their knowledge. This is a great example of possible way of keeping elderly people active and helpful for society

    Antineutrophil cytoplasmic antibodies in myelodysplasia.

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    Antibodies to neutrophil cytoplasmic antigens (ANCA) are good serological markers for patients with mainly vasculitic conditions. Two main types of ANCAs have been detected, the first termed cytoplasmic antineutrophil cytoplasmic antibody (cANCA) are mainly associated with patients with Wegener's granulomatosis, the other termed perinuclear antineutrophil cytoplasmic antibody (pANCA) are mainly associated with patients with renal vasculitis, rheumatic and collagen disorders. These antibodies are against various constituents of neutrophil granules. In patients with myelodysplasia, defects in normal granulocyte development are seen. We report a series of twelve patients with myelodysplasia of whom at least four showed a low titre and one a high titre of pANCA. Two of these patients also had demonstrable activity against myeloperoxidase (MPO). None of these patients had any evidence of systemic or cutaneous vasculitis or of any autoimmune disorder. There was no pANCA positivity in an age matched control group

    J.S. Bell's Concept of Local Causality

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    John Stewart Bell's famous 1964 theorem is widely regarded as one of the most important developments in the foundations of physics. It has even been described as "the most profound discovery of science." Yet even as we approach the 50th anniversary of Bell's discovery, its meaning and implications remain controversial. Many textbooks and commentators report that Bell's theorem refutes the possibility (suggested especially by Einstein, Podolsky, and Rosen in 1935) of supplementing ordinary quantum theory with additional ("hidden") variables that might restore determinism and/or some notion of an observer-independent reality. On this view, Bell's theorem supports the orthodox Copenhagen interpretation. Bell's own view of his theorem, however, was quite different. He instead took the theorem as establishing an "essential conflict" between the now well-tested empirical predictions of quantum theory and relativistic \emph{local causality}. The goal of the present paper is, in general, to make Bell's own views more widely known and, in particular, to explain in detail Bell's little-known mathematical formulation of the concept of relativistic local causality on which his theorem rests. We thus collect and organize many of Bell's crucial statements on these topics, which are scattered throughout his writings, into a self-contained, pedagogical discussion including elaborations of the concepts "beable", "completeness", and "causality" which figure in the formulation. We also show how local causality (as formulated by Bell) can be used to derive an empirically testable Bell-type inequality, and how it can be used to recapitulate the EPR argument.Comment: 19 pages, 4 figure

    Development of an integrated multi-species and multi-dose route PBPK model for volatile methyl siloxanes – D4 and D5

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    AbstractThere are currently seven published physiologically based pharmacokinetic (PBPK) models describing aspects of the pharmacokinetics of octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5) for various exposure routes in rat and human. Each model addressed the biological and physico-chemical properties of D4 and D5 (highly lipophilic coupled with low blood: air partition coefficient and high liver clearance) that result in unique kinetic behaviors as well differences between D4 and D5. However, the proliferation of these models resulted in challenges for various risk assessment applications when needing to determine the optimum model for estimating dose metrics. To enhance the utility of these PBPK models for risk assessment, we integrated the suite of structures into one coherent model capable of simulating the entire set of existing data equally well as older more limited scope models. In this paper, we describe the steps required to develop this integrated model, the choice of physiological, partitioning and biochemical parameters for the model, and the concordance of the model behavior across key data sets. This integrated model is sufficiently robust to derive relevant dose metrics following individual or combined dermal and inhalation exposures of workers, consumer or the general population to D4 and D5 for route-to-route, interspecies and high to low dose extrapolations for risk assessment

    90GHz and 150GHz observations of the Orion M42 region. A sub-millimeter to radio analysis

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    We have used the new 90GHz MUSTANG camera on the Robert C. Byrd Green Bank Telescope (GBT) to map the bright Huygens region of the star-forming region M42 with a resolution of 9" and a sensitivity of 2.8mJy/beam. 90GHz is an interesting transition frequency, as MUSTANG detects both the free-free emission characteristic of the HII region created by the Trapezium stars, normally seen at lower frequencies, and thermal dust emission from the background OMC1 molecular cloud, normally mapped at higher frequencies. We also present similar data from the 150GHz GISMO camera taken on the IRAM telescope. This map has 15" resolution. By combining the MUSTANG data with 1.4, 8, and 21GHz radio data from the VLA and GBT, we derive a new estimate of the emission measure (EM) averaged electron temperature of Te = 11376K by an original method relating free-free emission intensities at optically thin and optically thick frequencies. Combining ISO-LWS data with our data, we derive a new estimate of the dust temperature and spectral emissivity index within the 80" ISO-LWS beam toward OrionKL/BN, Td = 42K and Beta=1.3. We show that both Td and Beta decrease when going from the HII region and excited OMC1 interface to the denser UV shielded part of OMC1 (OrionKL/BN, Orion S). With a model consisting of only free-free and thermal dust emission we are able to fit data taken at frequencies from 1.5GHz to 854GHz.Comment: 18 pages, 8 figures, submitted to the Astrophysical Journa

    High‐contiguity genome assembly of the chemosynthetic gammaproteobacterial endosymbiont of the cold seep tubeworm Lamellibrachia barhami

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    Symbiotic relationships between vestimentiferan tubeworms and chemosynthetic Gammaproteobacteria build the foundations of many hydrothermal vent and hydrocarbon seep ecosystems in the deep sea. The association between the vent tubeworm Riftia pachyptila and its endosymbiont Candidatus Endoriftia persephone has become a model system for symbiosis research in deep‐sea vestimentiferans, while markedly fewer studies have investigated symbiotic relationships in other tubeworm species, especially at cold seeps. Here we sequenced the endosymbiont genome of the tubeworm Lamellibrachia barhami from a cold seep in the Gulf of California, using short‐ and long‐read sequencing technologies in combination with Hi‐C and Dovetail Chicago libraries. Our final assembly had a size of ~4.17 MB, a GC content of 54.54%, 137X coverage, 4153 coding sequences, and a CheckM completeness score of 97.19%. A single scaffold contained 99.51% of the genome. Comparative genomic analyses indicated that the L. barhami symbiont shares a set of core genes and many metabolic pathways with other vestimentiferan symbionts, while containing 433 unique gene clusters that comprised a variety of transposases, defence‐related genes and a lineage‐specific CRISPR/Cas3 system. This assembly represents the most contiguous tubeworm symbiont genome resource to date and will be particularly valuable for future comparative genomic studies investigating structural genome evolution, physiological adaptations and host‐symbiont communication in chemosynthetic animal‐microbe symbioses
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