International Evidence Review of Conditional (Suspended) Sentences: Final Report

This report reviews international use of conditional sentences, specifically understood to mean a criminal sentence of imprisonment which is suspended pending a person's satisfaction of specific criteria. These sentences are being considered in jurisdictions seeking ways of managing prison population growth. The laws and any information about use of such sentences among selected countries is considered in the first part. The second part reviews research on perceptions of such sentences, and community-based sentences generally. This research was requested by and submitted to the Scottish Government

Professional decision making and women offenders : containing the chaos?

This article draws on the findings from research undertaken in south-east Scotland in 2008 which sought to identify the characteristics of female offenders and to document the views of policy makers and practitioners regarding the experiences of women involved in the Scottish criminal justice system. Despite Scotland having retained a stronger 'welfare' focus than elsewhere in the UK (e.g. McAra, 2008), this is not reflected in the treatment of women who offend, with the rate of female imprisonment having almost doubled in the last ten years and community based disposals falling short of a welfare-oriented system. This article explores why the treatment that women offenders receive in the criminal justice system may be harsh and disproportionate both in relation to their offending and in relation to the treatment of men. It is argued that interventions with women need to be initiated earlier in their cycle of offending and at an earlier stage in the criminal justice process but also that the wide-ranging health, welfare, financial and behavioural needs of women who offend cannot be met solely within an increasingly risk-averse and punitive criminal justice environment

Strategies to Mitigate Seasonality of Production in Grassland-Based Systems

Key points 1. Fertilisation use and manipulation can cost-effectively alter species composition, increase seasonal herbage production and improve herbage quality. 2. Choice of suitable grassland species, varieties and mixtures offers opportunity to mitigate limitations of seasonal grassland production. 3. Special purpose fodder crops, cereals, shrubs and trees offer alternative or supplementary feed sources. 4. Manipulation of stocking rates, grazing systems, transhumance and pasture management at various times of the season are significant advantageous options. 5. Integration of different strategies is essential to mitigate seasonality in systems of animal production that must be inherently more sustainable over a longer time frame

Strategies to Mitigate Seasonality of Production in Grassland-Based Systems

Fertilisation use and manipulation can cost-effectively alter species composition, increase seasonal herbage production and improve herbage quality. Choice of suitable grassland species, varieties and mixtures offers opportunity to mitigate limitations of seasonal grassland production. Special purpose fodder crops, cereals, shrubs and trees offer alternative or supplementary feed sources. Manipulation of stocking rates, grazing systems, transhumance and pasture management at various times of the season are significant advantageous options. Integration of different strategies is essential to mitigate seasonality in systems of animal production that must be inherently more sustainable over a longer time frame

Managing Grassy Woodlands: Balancing Production and Conservation of Resources

Eastern Australian eucalypt woodlands are important agricultural areas that have been widely modified during two centuries of European-style use. Despite this they contain important natural resources including significant biodiversity. Long term sustainability of production depends on maintaining resources and management must be for both production and conservation. A research program on four properties in south east Queensland showed the properties were in generally good condition although all had some problems, and has highlighted a number of significant costs and barriers to adopting a more balanced approach to production and conservation

Listening and learning : the reciprocal relationship between worker and client

The relationship between worker and client has for the best part of 100 years been the mainstay of probation, and yet has recently been eroded by an increased emphasis on punishment, blame and managerialism. The views of offenders are in direct contradiction to these developments within the criminal justice system and this article argues that only by taking account of the views of those at the 'coal face' will criminologists, policy makers and practitioners be able to effect real change in crime rates. The article thus focuses on the views of a sample of previously persistent offenders in Scotland about offending, desistance and how the system can help them. It explores not only their need for friendship and support in youth but also the close association between relationships and the likelihood of offending. It also demonstrates the views of offenders themselves about the importance of the working relationship with supervising officers in helping them desist from crime. The article concludes that the most effective way of reducing offending is to re-engage with the message of the Probation Act of 100 years ago, namely, to 'advise, assist and befriend' offenders rather than to 'confront, challenge and change' offending behaviour

Contagious risk taking: social information and context influence wild jackdaws' responses to novelty and risk.

Although wild animals increasingly encounter human-produced food and objects, it is unknown how they learn to discriminate beneficial from dangerous novelty. Since social learning allows animals to capitalize on the risk-taking of others, and avoid endangering themselves, social learning should be used around novel and unpredictable stimuli. However, it is unclear whether animals use social cues equally around all types of novelty and at all times of year. We assessed whether wild, individually marked jackdaws-a highly neophobic, yet adaptable species-are equally influenced by social cues to consume novel, palatable foods and to approach a startling object. We conducted these tests across two seasons, and found that in both seasons observers were more likely to consume novel foods after seeing a demonstrator do so. In contrast, observers only followed the demonstrator in foraging next to the object during breeding season. Throughout the year more birds were wary of consuming novel foods than wary of approaching the object, potentially leading to jackdaws' greater reliance on social information about food. Jackdaws' dynamic social cue usage demonstrates the importance of context in predicting how social information is used around novelty, and potentially indicates the conditions that facilitate animals' adjustment to anthropogenic disturbance.A.L.G. is supported by the generosity of the Gates-Cambridge Trust. A.T. was supported by a BBSRC David Phillips Fellowship (BB/H021817/1).This is the final version of the article. It first appeared from Nature Publishing Group via http://dx.doi.org/10.1038/srep2776

An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells.

Duchenne muscular dystrophy is a progressive and incurable neuromuscular disease caused by genetic and biochemical defects of the dystrophin-glycoprotein complex. Here we show the regenerative potential of myogenic progenitors derived from corrected dystrophic induced pluripotent stem cells generated from fibroblasts of mice lacking both dystrophin and utrophin. We correct the phenotype of dystrophic induced pluripotent stem cells using a Sleeping Beauty transposon system carrying the micro-utrophin gene, differentiate these cells into skeletal muscle progenitors and transplant them back into dystrophic mice. Engrafted muscles displayed large numbers of micro-utrophin-positive myofibers, with biochemically restored dystrophin-glycoprotein complex and improved contractile strength. The transplanted cells seed the satellite cell compartment, responded properly to injury and exhibit neuromuscular synapses. We also detect muscle engraftment after systemic delivery of these corrected progenitors. These results represent an important advance towards the future treatment of muscular dystrophies using genetically corrected autologous induced pluripotent stem cells

Reducing the risk of iatrogenic Creutzfeldt–Jakob disease by improving the cleaning of neurosurgical instruments

Background: In all, there have been 178 variant Creutzfeldt–Jakob disease (vCJD) patients diagnosed in the UK, with an estimated maximum 1:2000 carriage rate based on archived appendix and tonsil tissue, implying that infection may be rare but carriage relatively frequent. Previous workers have identified that maintenance of surgical instruments in a humid atmosphere after use and prior to cleaning assists cleaning efficacy. Recently the Department of Health/Advisory Committee on Dangerous Pathogens UK have recommended a surgical instrument cleanliness threshold post cleaning of <5 μg protein per instrument side. Aim: To quantify cleanliness of neurosurgical instruments and to investigate cost-effective measures for improved cleaning. Methods: Two instrument protein quantification methods were used: one based on the International Standard (15883 series) using sodium dodecyl sulphate elution and ortho-phthalaldehyde reaction, and a second in-situ protein fluorescence detection system (ProReveal) providing results per instrument side. In-vitro investigation of the efficacy of some commercial and in-house pre-clean wetting agents was undertaken using artificial test soil and stainless steel discs under standard conditions. In-vivo evaluation of best-performing in-vitro agents was undertaken on craniotomy sets. Findings: ProReveal technology demonstrated that 163 out of 187 (87%) neurosurgical instruments had <5 μg residual protein per instrument side. The use of proprietary National Health Service plastic bags and sterile water-soaked wound pads were equivalent in efficacy to commercial pre-cleaning wetting products and significantly less expensive. Conclusion: Although we demonstrate low in-situ protein levels on neurosurgical instruments and the beneficial effects of keeping instruments moist, other cleaning critical-control points such as instrument loading patterns should also be monitored