PREDICTING FINANCIAL DISTRESS OF PUBLIC COMPANIES LISTED IN AMMAN STOCK EXCHANGE

This study investigates the role of a set of financial ratios in predicting financial distress of publicly listed companies in Jordan. Using Logistic Regression and Discriminant Analysis a comparison has been made between the two models to determine which is more appropriate to use as well as which of the financial ratios are statistically significant in predicting the financial distress of Jordanian companies. During the period 2007 to 2011, the results show that both logistic regression and discriminant analysis can predict financial distress, and that Return on Equity (ROE) and Return on Assets (ROA) are the most important two financial ratios, which help in predicting the financial distress of public companies listed in Amman stock Exchange

Chemical equivalence assessment of three brands of carbamazepine tablets and their anticonvulsant outcome on electrically-induced seizures in chicks

Assay for content of active ingredients is a critical test of drug quality; failure to meet up the standard for content of active ingredients will result to sub therapeutic quantities. Three brands (A, B and C) of carbamazepine were assayed to determine their chemical equivalence as well as their anticonvulsant activities. This was aimed at determining the possible relation between the chemical equivalence of the brands and their anticonvulsant outcomes. The brands were randomly selected from Community Pharmacies in Zaria, Kaduna State, and assayed for chemical equivalence to establish weight uniformity and identity; percentage content of active ingredients, using UV spectrophotometric analysis. Similarly all the brands were evaluated for anticonvulsant activity using maximal electroshock seizure model in chicks at doses of 20, 10 and 5 mg/kg. All the brands passed weight uniformity test as none of the tablets deviated from the mean by more than 7.5%. Similarly, their melting points were found to conform to standard average melting point (191oC) according to B.P. official monograph. However, the content of the active ingredients for Brands B and C did not conform to official standard of 95-105% while brand A conformed. Thus, the percentage contents for brands A, B and C were 99.49%, 76.02% and 87.59% respectively. Also, all the brands at the tested doses offered protection against seizures, ranging from 70-100%; but Brand C at 5 mg/kg offered only 40% quantal protection. The three brands of carbamazepine tablets were not chemically equivalent and their chemical equivalence indices could not be said to be the determinant of anticonvulsant effect.Key words: carbamazepine, anticonvulsant and chemical equivalenc

Effects of Phosphorus Fertilizer Application on Verano Stylo (\u3cem\u3eStylosanthes Hamata\u3c/em\u3e) for Fodder Production in Semi-Arid Nigeria

Profitable ruminant livestock production in Nigeria is often constrained by an inadequate. Although natural grazing lands provide most forage for most animals, these pastures like those throughout most of the tropical world, are grossly deficient in energy, crude protein and minerals, particularly during the dry season, and so cannot meet the requirements for meat and milk production (Akinolai et al. 2010). Sown pastures have proved to a valuable technology to improve livestock nutrition. However, a major limitation to the use of sown tropical species is infertile soil. This is certainly the case in the north western region of Nigeria where soils are very low in the phosphorus (P) content available to plants (Ezekiel and Gabriel 2006). Sakaba (2011) also reported very low available phosphorus content (\u3c 5 ppm) in the soil of the study area in Sokoto. Possible reasons for the low P status include: low pH value, excessive degradation caused by overgrazing and the effects of desertification. This study was conducted to evaluate the performance of Verano under different P fertilizer levels in the semi-arid ecosystem of northwestern Nigeria

Some behavioural studies on methanol root bark extract of Burkea africana (fabaceae) in mice

Burkea africana is a plant that belongs to then family Fabaceae; it is widely spread in tropical Africa including Nigeria. It is of valuable in ethnomedicine especially in the treatment of antidote for venomous stings and bites, cutaneous and sub cutaneous parasitic infection, convulsion and pulmonary troubles. The research was conducted to evaluate some central nervous system properties of the root bark methanol extractof B. africana in mice. It involved the following animal models: diazepam-induced sleep, hole-board and walking beam assay. Results: The methanol extract showed a significant decrease in the onset of sleep at doses of 40 mg/kg and 80 mg/kg (p<0.05); as well as produced significant increase in the duration of sleep (40 and 80 mg/kg) at p<0.05, p<0.005 respectively. The number of head dips significantly increased at 20 and 80 mg/kg (p<0.05 and 0.005 respectively). From the beam walking test for motor deficits, the result showed a significant increase in the number of foot slips at doses of 20 mg/kg (p<0.05); 40 and 80 mg/kg (p<0.005), where as there was no significant difference in the time taken to cross the two ends of the beam (time taken to complete the task). The median lethal dose (LD50) value of B. africana extract was found to be 288.5 mg/kg (i.p) in mice. The preliminary phytochemical screening revealed the presence of carbohydrates, saponins, flavonoid, aglycones, tannins, anthraquinones, cardiac glycosides, unsaturated steroids and triterpenes. Our results suggest that the B. africana extract contains biologically active compounds with potential sedative and anxiolytic properties.Key Words: Sedation, B. Africana, Diazepam, ethnomedicin

Assessment of the effect of dihydroartemisinin-sodium valproate combination on some behavioural activities in mice

Co-morbidity inevitably warrant occurrence of polypharmacy that may result in interactions or modification of either the therapeutic or toxic effect of any of the drugs employed. Malaria and epilepsy have been known to occur concurrently as such may necessitate the co-administration of two or more drugs. This study evaluated the effect of dihydroartemisinin-valproate combination on some behavioral activities related to central nervous system. The study was conducted using animal models as follows: maximal electroshock-induced seizures test in mice, diazepam-induced sleep in mice and mouse beam walking test for motor coordination deficit. Generally, the results showed that there were no statistical significant effects in the test models. Therefore, dihydroartemisinin did not significantly influence the protective effect of sodium valproate in convulsion; and did not significantly cause sedation in animals. Hence, the result of this study suggests that dihydroartemisinin-sodium valproate combination could be considered safe in seizures condition.Keywords: Dihydroartemisinin, Polypharmacy, Valproate, Drugs, Epileps

Effect of Weeding Regimes on Chemical Composition of Lablab Purpureus in Semi-Arid Sokoto, Nigeria

A Field experiment was conducted in 2010 and repeated in 2011 cropping seasons to determine effects of weeding regime on chemical composition of Lablab purpureus. It was planted and weeded at four weeding regimes (weedy check, weeding once, weeding twice and weed free) laid out in a Randomized Complete Block Design (RCBD) replicated thrice. Results revealed that weed free regime produced the highest crude protein (24.8%) while weedy check produced the highest carbohydrate content of 55.9% and the highest lipid content of 24.8%. For 2010 and 2011 seasons and the combined analysis, weeding regime did not show any significant difference (P > 0.05) in all parameters except in crude fibre and weed dry weight. Keywords: Weeding, Chemical Composition, Labla

Time Budget on Major Activities of Livestock Grazing Heterogeneous Natural Range and Crop Fields in Semi-Arid Nigeria

Semi-arid rangelands of West Africa provide herbs, trees and shrubs, which together with crop residues form the main sources of feed for the livestock population. Feed supply in this region is characterised by a progressive decline in quantity and quality with advancing dry season. It was reported that walking ability as well as watering frequencies affect the productivity of grazing livestock (Dicko and Sangare, 1984). This study tests the hypothesis that advancing season increases both time spent walking as well as feeding, with a switch from grazing to browsing