SPATIAL DISTRIBUTION REQUIREMENTS OF REFERENCE GROUND CONTROL FOR ESTIMATING LIDAR/INS BORESIGHT MISALIGNMENT

LiDAR (Light Detection and Ranging, also known as Airborne Laser Scanning – ALS) is a powerful technology for obtaining detailed and accurate terrain models as well as precise description of natural and man-made objects from airborne platforms, with excellent vertical accuracy. High performance integrated GPS/INS systems provide the necessary navigation information for the LiDAR data acquisition platform, and therefore, the proper calibration of the entire Mobile Mapping System (MMS) including individual and inter-sensor calibration, is essential to determine the accurate spatial  relationship of the involved sensors. In particular, the spatial relationship between the INS body frame and the LiDAR body frame is of high importance as it could be the largest source of systematic errors in airborne MMS. The feasibility of using urban areas, especially buildings, for boresight misalignment is still investigated. In this research, regularly or randomly distributed, photogrammetrically restituted buildings are used as reference surfaces, to investigate the impact of  the spatial distribution and the distance between the necessary ‘building-positions’ on boresight’s misalignment parameter estimation. The data used for performance evaluation included LiDAR point clouds Pothou, A. et al  777 and aerial images captured in a test area in London, Ohio, USA. The city includes mainly residential houses and a few bigger buildings

Finite measure for the initial conditions of inflation

We investigate whether inflation requires finely tuned initial conditions in order to explain the degree of flatness and homogeneity observed in the Universe. We achieve this by using the Eisenhart lift, which can be used to write any scalar field theory in a purely geometric manner. Using this formalism, we construct a manifold whose points represent all possible initial conditions for an inflationary theory. After equipping this manifold with a natural metric, we show that the total volume of this manifold is finite for a wide class of inflationary potentials. Hence, we identify a natural measure that enables us to distinguish between generic and finely tuned sets of initial conditions without the need for a regulator, in contrast to previous work in the literature. Using this measure, we find that the initial conditions that allow for sufficient inflation are indeed finely tuned. The degree of fine-tuning also depends crucially on the value of the cosmological constant at the time of inflation. Examining some concrete examples, we find that we require percent-level fine tuning if we allow the cosmological constant during inflation to be much larger than it is today. However, if we fix the cosmological constant to its presently observed value, the degree of fine tuning required is of order $10^{-54}$

Determination of Clinical Outcome in Mitral Regurgitation With Cardiovascular Magnetic Resonance Quantification

Background—Surgery for severe mitral regurgitation is indicated if symptoms or left ventricular dilation or dysfunction occur. However, prognosis is already reduced by this stage, and earlier surgery on asymptomatic patients has been advocated if valve repair is likely, but identifying suitable patients for early surgery is difficult. Quantifying the regurgitation may help, but evidence for its link with outcome is limited. Cardiovascular magnetic resonance (CMR) can accurately quantify mitral regurgitation, and we examined whether this was associated with the future need for surgery. Methods and Results—One hundred nine asymptomatic patients with echocardiographic moderate or severe mitral regurgitation had baseline CMR scans and were followed up for up to 8 years (mean, 2.5±1.9 years). CMR quantification accurately identified patients who progressed to symptoms or other indications for surgery: 91% of subjects with regurgitant volume ≤55 mL survived to 5 years without surgery compared with only 21% with regurgitant volume >55 mL (P40%. CMR-derived end-diastolic volume index showed a weaker association with outcome (proportions surviving without surgery at 5 years, 90% for left ventricular end-diastolic volume index <100 mL/m2 versus 48% for ≥100 mL/m2) and added little to the discriminatory power of regurgitant fraction/volume alone. Conclusions—CMR quantification of mitral regurgitation was associated with the development of symptoms or other indications for surgery and showed better discriminatory ability than the reference-standard CMR-derived ventricular volumes. CMR may be able to identify appropriate patients for early surgery, with the potential to change clinical practice, although the clinical benefits of early surgery require confirmation in a clinical trial

Hypertrophic pulmonary osteoarthropathy secondary to bronchial adenocarcinoma and coexisting pulmonary tuberculosis: a case report

A 44-year-old man presented with painful swelling of wrists and ankles, severe pain at both tibiae, clubbing of fingers and toes and arthritis in wrist and ankle joints. The chest roentgenogram showed consolidation of the right lower lobe, whereas plain roentgenograms revealed solid periosteal reaction at both tibiae. CT and bronchoscopy confirmed the presence of adenocarcinoma of the right lower lobe. Moreover, mycobacterium of tuberculosis was isolated by culture of the patient's sputum

Update of the European Association of Cardiovascular Imaging (EACVI) Core Syllabus for the European Cardiovascular Magnetic Resonance Certification Exam

An updated version of the European Association of Cardiovascular Imaging (EACVI) Core Syllabus for the European Cardiovascular Magnetic Resonance (CMR) Certification Exam is now available online. The syllabus lists key elements of knowledge in CMR. It represents a framework for the development of training curricula and provides expected knowledge-based learning outcomes to the CMR trainees, in particular those intending to demonstrate CMR knowledge in the European CMR exam, a core requirement in the CMR certification process

The AIQ Meta-Testbed: Pragmatically Bridging Academic AI Testing and Industrial Q Needs

AI solutions seem to appear in any and all application domains. As AI becomes more pervasive, the importance of quality assurance increases. Unfortunately, there is no consensus on what artificial intelligence means and interpretations range from simple statistical analysis to sentient humanoid robots. On top of that, quality is a notoriously hard concept to pinpoint. What does this mean for AI quality? In this paper, we share our working definition and a pragmatic approach to address the corresponding quality assurance with a focus on testing. Finally, we present our ongoing work on establishing the AIQ Meta-Testbed.Comment: Accepted for publication in the Proc. of the Software Quality Days 2021, Vienna, Austri

Accelerating global left-ventricular function assessment in mice using reduced slice acquisition and three-dimensional guide-point modelling

<p>Abstract</p> <p>Background</p> <p>To investigate the utility of three-dimensional guide-point modeling (GPM) to reduce the time required for CMR evaluation of global cardiac function in mice, by reducing the number of image slices required for accurate quantification of left-ventricular (LV) mass and volumes.</p> <p>Methods</p> <p>Five female C57Bl/6 mice 8 weeks post myocardial infarction induced by permanent occlusion of the left coronary artery, and six male control (un-operated) C57Bl/6 mice, were subject to CMR examination under isoflurane anaesthesia. Contiguous short axis (SAX) slices (1 mm thick 7-9 slices) were obtained together with two long axis (LAX) slices in two chamber and four chamber orientations. Using a mathematical model of the heart to interpolate information between the available slices, GPM LV mass and volumes were determined using full slice (all SAX and two LAX), six slice (four SAX and two LAX) and four slice (two SAX and two LAX) analysis protocols. All results were compared with standard manual volumetric analysis using all SAX slices.</p> <p>Results</p> <p>Infarct size was 39.1 ± 5.1% of LV myocardium. No significant differences were found in left ventricular mass and volumes between the standard and GPM full and six slice protocols in infarcted mice (113 ± 10, 116 ± 11, and 117 ± 11 mg respectively for mass), or between the standard and GPM full, six and four slice protocols in control mice, (105 ± 14, 106 ± 10, 104 ± 12, and 105 ± 7 mg respectively for mass). Significant differences were found in LV mass (135 ± 18 mg) and EF using the GPM four slice protocol in infarcted mice (p < 0.05).</p> <p>Conclusion</p> <p>GPM enables accurate analysis of LV function in mice with relatively large infarcts using a reduced six slice acquisition protocol, and in mice with normal/symmetrical left-ventricular topology using a four slice protocol.</p