The spectrum of Apert syndrome: phenotype, particularities in orthodontic treatment, and characteristics of orthognathic surgery

In the PubMed accessible literature, information on the characteristics of interdisciplinary orthodontic and surgical treatment of patients with Apert syndrome is rare. The aim of the present article is threefold: (1) to show the spectrum of the phenotype, in order (2) to elucidate the scope of hindrances to orthodontic treatment, and (3) to demonstrate the problems of surgery and interdisciplinary approach. Children and adolescents who were born in 1985 or later, who were diagnosed with Apert syndrome, and who sought consultation or treatment at the Departments of Orthodontics or Craniomaxillofacial Surgery at the Dental School of the University Hospital of Münster (n = 22; 9 male, 13 female) were screened. Exemplarily, three of these patients (2 male, 1 female), seeking interdisciplinary (both orthodontic and surgical treatment) are presented. Orthodontic treatment before surgery was performed by one experienced orthodontist (AH), and orthognathic surgery was performed by one experienced surgeon (UJ), who diagnosed the syndrome according to the criteria listed in OMIM™. In the sagittal plane, the patients suffered from a mild to a very severe Angle Class III malocclusion, which was sometimes compensated by the inclination of the lower incisors; in the vertical dimension from an open bite; and transversally from a single tooth in crossbite to a circular crossbite. All patients showed dentitio tarda, some impaction, partial eruption, idopathic root resorption, transposition or other aberrations in the position of the tooth germs, and severe crowding, with sometimes parallel molar tooth buds in each quarter of the upper jaw. Because of the severity of malocclusion, orthodontic treatment needed to be performed with fixed appliances, and mainly with superelastic wires. The therapy was hampered with respect to positioning of bands and brackets because of incomplete tooth eruption, dense gingiva, and mucopolysaccharide ridges. Some teeth did not move, or moved insufficiently (especially with respect to rotations and torque) irrespective of surgical procedures or orthodontic mechanics and materials applied, and without prognostic factors indicating these problems. Establishing occlusal contact of all teeth was difficult. Tooth movement was generally retarded, increasing the duration of orthodontic treatment. Planning of extractions was different from that of patients without this syndrome. In one patient, the sole surgical procedure after orthodontic treatment with fixed appliances in the maxilla and mandible was a genioplasty. Most patients needed two- jaw surgery (bilateral sagittal split osteotomy [BSSO] with mandibular setback and distraction in the maxilla). During the period of distraction, the orthodontist guided the maxilla into final position by means of bite planes and intermaxillary elastics. To our knowledge, this is the first article in the PubMed accessible literature describing the problems with respect to interdisciplinary orthodontic and surgical procedures. Although the treatment results are not perfect, patients undergoing these procedures benefit esthetically to a high degree. Patients need to be informed with respect to the different kinds of extractions that need to be performed, the increased treatment time, and the results, which may be reached using realistic expectations

Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae)

Este artículo contiene 138 páginas, 213 figuras, 14 tablas.Diplura is a group of entognathous hexapods, often considered a sister group to insects. They play an important role in recycling organic matter in soil and subterranean terrestrial ecosystems. The Campodeidae is the most diverse family, divided into four subfamilies. The subfamily Plusiocampinae has a subterranean life-style with many species distributed in the Euro-Mediterranean area. The incertae sedis tachycampoids (“lignée Tachycampoïde”) is a group within the family Campodeidae that share with the Plusiocampinae a strong preference for subterranean habitats and several morphological characters, such as slender body shape, elongated appendages, considerable increment in the number of antennomeres and cercal articles, and complexity of sensorial structures. The present monograph provides a taxonomic revision of the subfamily Plusiocampinae and the genera belonging to the tachycampoid lineage from Europe and the Mediterranean region. It comprises detailed morphological descriptions and illustrations together with data on the habitats and distributions of 87 species, 10 subspecies and 11 affinis forms. Seven new species are described among those, namely: Plusiocampa (Plusiocampa) apollo Sendra, Giachino & Vailati sp. nov., P. (P.) chiosensis Sendra & Gasparo sp. nov., P. (P.) dublanskii Sendra & Turbanov sp. nov., P. (P.) hoffmanni Sendra & Paragamian sp. nov., P. (P.) rhea Sendra sp. nov., P. (P.) ternovensis Sendra & Borko sp. nov. and P. (Venetocampa) ferrani Sendra & Delić sp. nov.DS’s field trips were funded by the Serbian Ministry of Education, Science and Technology (Grant 173038); KP was partially funded by the HISR project “Conservation of the Cave Fauna of Greece” funded by the MAVA Foundation and WWF Greece; PMG and DV carried out sampling in Greece using permits from the Ministry of Environment no. 124085/1362/2015, 135366/373/2016 and 166238/248/2018; IT was funded within the framework of the state assignment of FASO Russia (themes no. АААА-А18-118012690106-7 and АААА-А18-118012690105), supported in part by RFBR (project no. 17-54-40017Абх_а); sampling efforts by AF and colleagues resulted from various projects on the evolution of cave fauna diversity, some of them funded by the German Research Foundation, DFG (DFG FA 1042/1-1 and DFG BA 2152/14-1); PMG and DV were partly supported by the program “Research Missions in the Mediterranean Basin” sponsored by the World Biodiversity Association onlus XLI contribution; ASPSR was supported by a research grant (15471) from Villum Fonden.Peer reviewe

Figs 155–156 in Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae)

Figs 155–156. Plusiocampa (Plusiocampa) ternovensis Sendra & Borko sp. nov. 155. Paratype, ♂, 4.7 mm long (PMSL Diplura-002); urosternite I, left side. 156. ♀, 5.3 mm long (Coll. AS); urosternite I, left side. Scale bar: 0.1 mm.Published as part of Sendra, Alberto, Antić, Dragan, Barranco, Pablo, Borko, Špela, Christian, Erhard, Delić, Teo, Fadrique, Floren, Faille, Arnaud, Galli, Loris, Gasparo, Fulvio, Georgiev, Dilian, Giachino, Pier Mauro, Lukić, Marko, Marcia, Paolo, Miculinić, Kazimir, Nicolosi, Giuseppe, Palero, Ferran, Paragamian, Kaloust, Pérez, Toni, Polak, Slavko, Prieto, Carlos E., Turbanov, Ilya, Vailati, Dante & Reboleira, Ana Sofia P. S., 2020, Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae), pp. 1-138 in European Journal of Taxonomy 591 on page 94, DOI: 10.5852/ejt.2020.591, http://zenodo.org/record/365982

Figs 71–76 in Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae)

Figs 71–76. Plusiocampa (Plusiocampa) hoffmanni Sendra & Paragamian sp. nov., from Varathro Stou Bokou ton Poro, Krousonas, Crete (71–74) and Varathro Mythia Kabathoura, Rethymno, Crete (75–76) (Coll. AS). 71. Femur of metathoracic leg. 72. Dorsal femoral macroseta, metathoracic leg. 73. Dorsolateral view of pretarsus, posterior claw in the foreground. 74. Detail of preceding, posterior claw in the foreground. 75. End of tarsus, with pretarsus in ventral view. 76. Pretarsus, ventral view.Published as part of Sendra, Alberto, Antić, Dragan, Barranco, Pablo, Borko, Špela, Christian, Erhard, Delić, Teo, Fadrique, Floren, Faille, Arnaud, Galli, Loris, Gasparo, Fulvio, Georgiev, Dilian, Giachino, Pier Mauro, Lukić, Marko, Marcia, Paolo, Miculinić, Kazimir, Nicolosi, Giuseppe, Palero, Ferran, Paragamian, Kaloust, Pérez, Toni, Polak, Slavko, Prieto, Carlos E., Turbanov, Ilya, Vailati, Dante & Reboleira, Ana Sofia P. S., 2020, Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae), pp. 1-138 in European Journal of Taxonomy 591 on page 59, DOI: 10.5852/ejt.2020.591, http://zenodo.org/record/365982

Figs 9–11 in Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae)

Figs 9–11. Plusiocampa (Plusiocampa) apollo Sendra, Giachino & Vailati sp. nov. 9–10. Holotype, ♀, 4.8 mm long, from Viotìa, O. Pamassós, Greece (MZB 2019-1032). 9. Pronotum, mesonotum and metanotum (s = setiform sensillum). 10. Urotergites I–VII and abdominal segment IX, right side (s = setiform sensillum). 11. Paratype, ♂, 6.4 mm long, from the type locality (Coll. AS); urosternite I, left side. Scale bars: 9–10 = 30 μm; 11 = 10 μm.Published as part of Sendra, Alberto, Antić, Dragan, Barranco, Pablo, Borko, Špela, Christian, Erhard, Delić, Teo, Fadrique, Floren, Faille, Arnaud, Galli, Loris, Gasparo, Fulvio, Georgiev, Dilian, Giachino, Pier Mauro, Lukić, Marko, Marcia, Paolo, Miculinić, Kazimir, Nicolosi, Giuseppe, Palero, Ferran, Paragamian, Kaloust, Pérez, Toni, Polak, Slavko, Prieto, Carlos E., Turbanov, Ilya, Vailati, Dante & Reboleira, Ana Sofia P. S., 2020, Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae), pp. 1-138 in European Journal of Taxonomy 591 on page 27, DOI: 10.5852/ejt.2020.591, http://zenodo.org/record/365982

Quality issues in georeferencing: from physical collections to digital data repositories for ecological research

Natural history collections constitute an enormous wealth of information of Life on Earth. It is estimated that over 2 billion specimens are preserved at institutions worldwide, of which less than 10% are accessible via biodiversity data aggregators such as GBIF. Moreover, they are a very important resource for eco¿evolutionary research, which greatly depends on knowing the precise location where the specimens were collected in order to characterize the environment in which they lived. Yet, only about 55% of the accessible records are georeferenced and only 31% have coordinate uncertainty information, which is critical for conducting rigorous studies. The awareness of this gap of knowledge which hinders the enormous potential of such data in research led to the organization of a workshop which brought together key players in georeferencing of natural history collections. The discussion and outcomes of this workshop are here presented

A collaborative backbone resource for comparative studies of subterranean evolution: The World Asellidae database

Abstract Transition to novel environments, such as groundwater colonization by surface organisms, provides an excellent research ground to study phenotypic evolution. However, interspecific comparative studies on evolution to groundwater life are few because of the challenge in assembling large ecological and molecular resources for species‐rich taxa comprised of surface and subterranean species. Here, we make available to the scientific community an operational set of working tools and resources for the Asellidae, a family of freshwater isopods containing hundreds of surface and subterranean species. First, we release the World Asellidae database (WAD) and its web application, a sustainable and FAIR solution to producing and sharing data and biological material. WAD provides access to thousands of species occurrences, specimens, DNA extracts and DNA sequences with rich metadata ensuring full scientific traceability. Second, we perform a large‐scale dated phylogenetic reconstruction of Asellidae to support phylogenetic comparative analyses. Of 424 terminal branches, we identify 34 pairs of surface and subterranean species representing independent replicates of the transition from surface water to groundwater. Third, we exemplify the usefulness of WAD for documenting phenotypic shifts associated with colonization of subterranean habitats. We provide the first phylogenetically controlled evidence that body size of males decreases relative to that of females upon groundwater colonization, suggesting competition for rare receptive females selects for smaller, more agile males in groundwater. By making these tools and resources widely accessible, we open up new opportunities for exploring how phenotypic traits evolve in response to changes in selective pressures and trade‐offs during groundwater colonization