A study of thrombocytopenia in malaria and its prognostic significance

Background:Malaria is one of the most common infectious diseases of tropics, affecting 300-500 million people and causing over 1 million deaths each year in the world. Malaria is a multisystem infection and can be associated with many complications. Thrombocytopenia is the most common hematological complication of malaria, but association of thrombocytopenia with different types of malaria and its prognostic implications in context with severity of low platelet count has not been evaluated in many of previous studies. Objectives of the study was to study the incidence, correlation of severity and prognostic significance of thrombocytopenia in malaria.Methods: A total of 100 cases were included in the study and identified positive for malaria parasites on peripheral smear examination with conventional microscopy and /or by rapid diagnostic test.Results: Present study includes 100 patient with malaria from which 78% were males and 22% were females. Most of the patients were suffering from P. vivax malaria (65%), and rest suffered from P. falciparum malaria (32%) and mixed infection (03%). Incidence of thrombocytopenia was 79%, of which mild, moderate and severe thrombocytopenia was 35.44%, 41.77% and 22.78% respectively. Complicated and uncomplicated malaria cases were 22.79% and 77.21% respectively.Conclusion: Clinical bleeding in severe malaria is not a common feature and occurred in 5.5% of individuals with severe disease. Unnecessary platelet transfusion is not required for mild to moderate degree of thrombocytopenia in malaria patients which further avoids an unnecessary cost burden in the poor group of patients.

Methodology to map spatial variability of available nutrients in area of intensively growing potato (Solanum tuberosum) using remote sensing and GIS

A methodology is developed for mapping spatial variability of available nutrients of soils of a pocket growing potato (Solanum tuberosum L.) crop using GIS. For this purpose potato growing pockets of the Jalandhar district were demarcated based on the available information, ground truth and classification of the IRS P6 AWiFS image. The classified potato area in the image was taken as background to generate the sampling site map and representative soil samples of potato fields from these sites were collected along with geographical coordinates using GPS receiver(ETREX-VISTA, Garmin). Values of different parameters (like pH, OC, available P and K and micronutrients) were tagged with corresponding points and interpolation maps for each individual parameters were prepared using suitable semivariogram and kriging in remote sensing GIS software. These prepared maps were further classified giving suitable ranges of different soil parameters

Breeding tomato (Solanum lycopersicum L.) for resistance to biotic and abiotic stresses

Tomato (Solanum lycopersicum L.) is an important vegetable crop cultivated in the tropical and sub-tropical regions of the world. Low productivity in India is due to occurrence of both biotic and abiotic stresses. Among the biotic stresses, tomato leaf curl disease, bacterial wilt, early blight and Groundnut Bud Necrosis Virus disease have become serious production constraints causing considerable yield loss in the major tomato growing areas of the country. Adoption of multiple disease resistant varieties or F1 hybrids would be the most appropriate way to address these diseases. At ICAR-IIHR, Bengaluru systematic breeding strategies were employed to pyramid genes for resistance to early blight, bacterial wilt and tomato leaf curl diseases and to develop advanced breeding lines& F1 hybrids with triple disease resistance. Stable source of resistance to early blight and bi-partite begomo-virus (Tomato Leaf Curl New Delhi Virus) has been identified in Solanum habrochaites LA-1777. Validation with molecular markers linked to tomato leaf curl virus resistance revealed that LA-1777 carryTy2 and other putative resistant genes. Several high yielding dual purpose hybrids were also developed for fresh market and processing with high level of resistance to multiple diseases. Cherry tomato lines have also been bred for high TSS, total carotenoids, total phenols, flavonoids, vitamin C, acidity and lycopene content. IIHR-249-1, IIHR-2101 (Solanum habrochaites LA-1777), IIHR- 2866 and IIHR-2864 recorded high values for quality parameters like total carotenoids, lycopene, vitamin C, total phenols, flavonoids and TSS. Drought tolerant root stock has been developed by an interspecific cross between S. habrochaites LA-1777 and S. lycopersicum (15 SB SB). Resistant sources have also been identified against Tuta absoluta, a serious insect pest reported from major tomato growing areas in the country in recent time. High temperature tolerant breeding lines are in pipe line

DETECTION OF SOMACLONAL VARIATIONS AMONG MICROPROPAGATED POPULATION OF SOME IMPORTANT MEDICINAL PLANTS

Demand of healthy medicinal planting material in India and international drug market is increasing continually, while, many important medicinal plants have been declared endangered due to less seed viability, low germination percent and vegetative propagation also susceptible for disease. Plant tissue culture has come up as an alternative of poor natural germination of seed and vegetative propagation which provides desired number genetically uniform pest free plants in a short span of time. One of the major problems of in vitro plant cultivation is the high incidence of somaclonal variation. The RAPD analysis was carried out to assess genetic relationship among micropropagated population the basis of scoring of band exhibited by amplified products using NTSYS_pc. RAPD and ISSR marker were used to assess clonal fidelity of medicinal plants viz., Chlorophytum borivilianum, Bacopa monnieri, Rauwolfia serpentina and Oroxylum indicum. Initial screening for somaclonal variation on the basis of morphological traits was carried out starting second month of culture. Among six to eighth month old culture

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Not AvailableThe present study was carried out at Central Potato Research Institute, Shimla for three years to work out the nitrogen requirement of french bean and competition in potato + french bean (1:1) intercropping system. Application of 100% N to French bean, gave 29% higher pod yield than sole cropping, on area basis, however, the mean yield of french bean pods with 100% N was statistically at par with that under 50% N and significantly higher over 0 or 25% N. Land Equivalent Ratio (LER) values were >1 at all N levels to French bean, the highest being 1.296 with 100% of N to french bean. The relative crowding coefficient (RCC) values of both the crops were more than one indicating that both the crops produced greater than ‘expected’ yields under intercropping, however, the aggressivity values indicated that french bean was a dominant species whereas potato was dominated species in intercropping, irrespective of N dose to french bean i.e. the extent of proportionate yield increase of french bean was more than potato in intercropping. The competition ratio also showed that french bean was more competitive than potato when fertilized properly. There was a positive mean balance of NPK and 36-68% of applied N, 64-74% of applied P and 44-77% of applied K was left as residual fertility under various intercropping treatments. Intercropping also gave higher net returns (Rs. 69 to 82 thousand/ha) and benefit:-cost ratio (2.43 to 2.66) than sole cropping of either of the crop. It can be concluded from the study that in potato + French bean (1:1) intercropping in north- western hills, N dose to french bean can be reduced by 50% without impairing soil health in terms of NPK balance Effect of nitrogen application to intercrops on yield, competition, nutrient use efficiency and economics in potato (Solanum Tuberosum L.) + French bean (Phaseolus Vulgaris L.) system in north-western hills of India | Request PDF. Available from: https://www.researchgate.net/publication/317200462_Effect_of_nitrogen_application_to_intercrops_on_yield_competition_nutrient_use_efficiency_and_economics_in_potato_Solanum_Tuberosum_L_French_bean_Phaseolus_Vulgaris_L_system_in_north-western_hills_of_ [accessed Oct 03 2018].Not Availabl

Influence of Socio-Economic Factors on Risk Management Strategies among Generation Z in India pertaining to Health: A Post-Pandemic Analysis

This study aims to examine the factors influencing the adoption of health insurance and buy intention among Generation Z in India during the period after the COVID-19 pandemic. The COVID-19 pandemic has highlighted the significance of healthcare readiness and fiscal stability, hence emphasizing the crucial role of health insurance in the lives of individuals and households. Generation Z, encompassing individuals born approximately from the mid-1990s to the early 2010s, constitutes a noteworthy demographic cohort characterised by distinct inclinations and conduct. This study investigates the demographic features of individuals, their level of knowledge and awareness regarding health insurance, their attitudes towards risk, and the influence of the pandemic on their perceptions. Preliminary data suggest that the Gen Z population in India understands the significance of health insurance. However, some obstacles impede their adoption of such insurance, including a lack of comprehensive knowledge, budgetary limitations, and a tendency to prioritise immediate financial objectives. Moreover, the ongoing global pandemic has significantly impacted individuals’ perception of healthcare risks and financial planning, potentially affecting their inclination to allocate resources towards health insurance investments. This study enhances our comprehension of the changing patterns of health insurance adoption in India, specifically among the youngest cohort, and offers valuable insights for insurers, policymakers, and healthcare providers to customise their offerings and communication approaches in order to effectively address the requirements of Generation Z in the aftermath of the pandemic. In conclusion, promoting the adoption of health insurance among this particular cohort has the potential to enhance financial resilience and facilitate improved access to healthcare for future generations in Indi

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