18 research outputs found

    POWERING CUSTOMER CONNECTIVITY OF PRODUCTS WITH LAST MILE SUPPORT SERVICES: EVIDENCES FROM INDIAN PASSENGER CAR MANUFACTURING

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    The paper highlights post-production customer connectivity processes in an automobile manufacturing set-up. Identity of post-production processes has been established as a unique in company service operations or pseudo-manufacturing activities. Consequently this research observes that handling these activities purely with a manufacturing focus or with a pure service focus would not be that effective. This paper in-turn proposes a new approach to powering the customer connectivity process in the last mile of a product’s journey from manufacturing to market. The scenario has been addressed in three domains, viz., Post-Production pre-market functions, Product Installation, and Product Liabilities. Through a composite process map of the post-production situations it captures the order winning elements  to pick up opportunities for the possible reinforcement of adding value for money in the last mile activities on the product from company to customer.

    The distribution of standard deviations applied to high throughput screening

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    High throughput screening (HTS) assesses compound libraries for “activity” using target assays. A subset of HTS data contains a large number of sample measurements replicated a small number of times providing an opportunity to introduce the distribution of standard deviations (DSD). Applying the DSD to some HTS data sets revealed signs of bias in some of the data and discovered a sub-population of compounds exhibiting high variability which may be difficult to screen. In the data examined, 21% of 1189 such compounds were pan-assay interference compounds. This proportion reached 57% for the most closely related compounds within the sub-population. Using the DSD, large HTS data sets can be modelled in many cases as two distributions: a large group of nearly normally distributed “inactive” compounds and a residual distribution of “active” compounds. The latter were not normally distributed, overlapped inactive distributions – on both sides –, and were larger than typically assumed. As such, a large number of compounds are being misclassified as “inactive” or are invisible to current methods which could become the next generation of drugs. Although applied here to HTS, it is applicable to data sets with a large number of samples measured a small number of times

    Inter relationship between some routine semen evaluation parameters in Jersey X local hill cattle crossbred bulls

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    The present study was conducted with an objective of establishing a relationship between various routine semen evaluation parameters. Work was conducted at Sperm Station Palampur, Himachal Pradesh, on the semen from five Jersey X local hill cattle crossbred breeding bulls. A total of 40 ejaculates (8 from each bull), were analysed at five different stages of processing namely post dilution, post equilibration, post thaw and after 1 and 2 hours incubation post thaw at 37°C for progressive motility, live dead count, reaction to hypo-osmotic solution, acrosomal integrity and gross morphological abnormalities. The results of the study revealed a highly significant (P<0.01) correlation between the various semen evaluation parameters except for the gross morphological abnormalities where there was a significant (P<0.05) negative correlation between the acrosomal integrity and gross morphological abnormalities

    Inter relationship between some routine semen evaluation parameters in Jersey X local hill cattle crossbred bulls

    Get PDF
    The present study was conducted with an objective of establishing a relationship between various routine  semen evaluation parameters. Work was conducted at Sperm Station Palampur, Himachal Pradesh, on the  semen from five Jersey X local hill cattle crossbred breeding bulls. A total of 40 ejaculates (8 from each bull),  were analysed at five different stages of processing namely post dilution, post equilibration, post thaw and  after 1 and 2 hours incubation post thaw at 37°C for progressive motility, live dead count, reaction to  hypo-osmotic solution, acrosomal integrity and gross morphological abnormalities. The results of the study  revealed a highly significant (P&lt;0.01) correlation between the various semen evaluation parameters except for  the gross morphological abnormalities where there was a significant (P&lt;0.05) negative correlation  between the acrosomal integrity and gross morphological abnormalities.Keywords: Acrosome, Crossbred bulls, HOST, Semen
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