2,388 research outputs found

    "Foodies" and their travel preferences

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    This articles examines the propensity of Australian food lovers, or “foodies,” to travel both domestically and internationally for food-related experiences. Data are analyzed from a survey of food lovers in Australia, profiling their characteristics, pertinent travel behavior, desired experiences, trip and destination preferences, with special attention given to isolating characteristics and preferences of those who had already traveled for food-related experiences. In the conclusions we make recommendations for destinations seeking to develop food tourism, in effect providing a demand-based planning and marketing approach. A principal conclusion is that they are highly involved with food, think of themselves as gourmets, and they desire a multifaceted holiday. Core experiences include consumption of authentic cuisine, learning about food/beverages and gastronomic traditions, and socializing. These must be augmented through opportunities for broader cultural, natural, touring, and shopping experiences. Recommendations are made for extending this line of research and theory development

    Cantilever-based Resonant Gas Sensors with Integrated Recesses for Localized Sensing Layer Deposition

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    This work presents mass-sensitive hammerhead resonators with integrated recesses as a gas-phase chemical microsensor platform. Recesses are etched into the head region of the resonator to locally deposit chemically sensitive polymers by ink-jet printing. This permits the sensing films to be confined to areas that (a) are most effective in detecting mass loading and (b) are not strained during the in-plane vibrations of the resonator. As a result of the second point, even 5-μm thick polymer coatings on resonators with a 9-12 μm silicon thickness barely affect the Q-factor in air. This translates into higher frequency stability and ultimately higher sensor resolution compared to uniformly coated devices

    Cytoplasmic inheritance of rutamycin resistance in mouse fibroblasts.

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    Development of a high-throughput microsatellite typing approach for forensic and population genetic analysis of wild and domestic African Bovini

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    Conservation management and forensic traceability of African buffalo and cattle rely on the timely provision of unbiased and accurate genetic information. An approach in which 17 cattle microsatellite markers are co-electrophoresed, following amplification in three core multiplex reactions was established for this purpose. Mean allelic richness per locus was 8.24 and 6.47, for buffalo and Bonsmara cattle, respectively, whilst an unbiased match probability of 6.5x×10-17 and 1.03 × 10-16 was obtained for each. These results confirm the usefulness of this rapid, cost-effective typing approach for forensic, paternity and fine-scale genetic analyses of wild and domestic African Bovini tribe member

    Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis

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    Cardiovascular disease remains a major cause of morbidity and mortality in the westernized world. Atherosclerosis is the underlying cause of most cardiovascular diseases. Atherosclerosis is a slowly evolving chronic inflammatory disorder involving the intima of large and medium sized arteries that is initiated in response to high plasma lipid levels, especially LDL. Cells of both the innate and adaptive immunity are involved in this chronic inflammation. Although high plasma LDL levels are a major contributor to most stages of the evolution of atherosclerosis, HDL and its major protein apoA-I possess properties that attenuate and may even reverse atherosclerosis. Two major functions are the ability to induce the efflux of cholesterol from cells, particularly lipid-loaded macrophages, in the artery wall for transfer to the liver, a process referred to as reverse cholesterol transport, and the ability to attenuate the pro-inflammatory properties of LDL. The removal of cellular cholesterol from lipid-loaded macrophages may also be anti-inflammatory. One of the most promising therapies to enhance the anti-atherogenic, anti-inflammatory properties of HDL is apoA-I mimetic peptides. Several of these peptides have been shown to promote cellular cholesterol efflux, attenuate the production of pro-inflammatory cytokines by macrophages, and to attenuate the pro-inflammatory properties of LDL. This latter effect may be related to their high affinity for oxidized lipids present in LDL. This review discusses the functional properties of the peptides and their effect on experimental atherosclerosis and the results of initial clinical studies in humans

    Food events in lifestyle and travel

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    A large-scale survey of food lovers revealed the critical importance of planned events in their lifestyles and travel. Details provided in this article include participation frequencies for various food-related events, segmentation based on food-event attendance, and the differences between segments in terms of preferences for enjoyment events versus learning events. The small segment most likely to travel for food experiences, called dynamic foodies, prefers specialist learning events. The much larger segment, called active foodies, prefers enjoyment events, suggesting that higher levels of involvement translate into demand for more specialized benefits. Conclusions are drawn for food events and their marketing, and for destination development and marketing to food tourists. Research needs are identified

    Suite of simple metrics reveals common movement syndromes across vertebrate taxa

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    ecause empirical studies of animal movement are most-often site- and species-specific, we lack understanding of the level of consistency in movement patterns across diverse taxa, as well as a framework for quantitatively classifying movement patterns. We aim to address this gap by determining the extent to which statistical signatures of animal movement patterns recur across ecological systems. We assessed a suite of movement metrics derived from GPS trajectories of thirteen marine and terrestrial vertebrate species spanning three taxonomic classes, orders of magnitude in body size, and modes of movement (swimming, flying, walking). Using these metrics, we performed a principal components analysis and cluster analysis to determine if individuals organized into statistically distinct clusters. Finally, to identify and interpret commonalities within clusters, we compared them to computer-simulated idealized movement syndromes representing suites of correlated movement traits observed across taxa (migration, nomadism, territoriality, and central place foraging)

    PCSK9 in South African Variants of Familial Hypercholesterolemia∗

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