Uncertainties in lava flow hazard maps derived from numerical simulations: the case study of Mount Etna

The procedure for the derivation of a hazard map for lava flows at Mount Etna through lava flow simulations is critically reviewed. The DOWNFLOW code is then used to explore the sensitivity of the hazard map with respect to input settings. Three parameters are varied within ranges close to values recently applied to derive similar hazard maps: (i) the spacing between computational vents; (ii) the spatial probability density function (PDF) for future vent opening; and (iii) the expected length of future lava flows. The effect of increasing the spacing between computational vents tends to be compensated at the lower elevations, and a vent spacing smaller than about 500 m warrants an overall difference with respect to a reference map which is smaller than 6–8%. A random subsampling of the elements used to obtain the input vent opening PDF (−20%, −40% and −60%) originates significant but drastically smaller differences in the obtained map with respect to the reference one (~10%, ~12.5% and ~17% respectively, on average). In contrast, our results show that changes in the expected flow length originate, by far, the highest changes in the obtained hazard map, with overall differences ranging between ~20% and ~65%, and between ~30% and ~95% if computed only over inhabited areas. The simulations collected are further processed to derive maps of the confluence/diffluence index,which quantifies the error introduced, locally, when the position of the vent is misplaced by a given distance

A Microscopic Information System (MIS) for petrographic analysis

The database and visualization facilities of Geographic Information System (GIS) software are employed to support the analysis of rock texture from thin section by image processing. A Microscopic Information System (MIS) is hence obtained. The method is applied to transmitted light images of 137 samples obtained from 8 granitoid rocks. A slide scanner and a mount for crossed polarization are used to acquire the input images. For each thin section 5 collimated RGB images are scanned: 4 under different directions of crossed polarization and 1 without polarization. A grain segmentation procedure, based on two region growing functions is applied. The output is converted to vector format and refined using editing tools in the MIS environment, which enables a straightforward match between the input imagery and the final vectorized texture. GIS software provides optimal management of the MIS database, allowing the cumulative measurement of more than 87 000 grains

Capturing full resolution perspective and stereo views of large DEMs

A custom software to capture still views of images draped on digital surfaces is presented. It is called ViCam (for virtual camera). Unlike off the shelf software packages, our system is completely controlled by the user, allowing the visualization of a scene from an arbitrary viewpoint with an arbitrary (virtual) optic geometry (i.e. field of view angle). This software can work in loop over very large tiled datasets handled by a Geographic Information System (GIS) package, providing in output global views of the entire input area as single and seamless image layers at any desired resolution. Output image layers can be derived also in stereo anaglyph mode, allowing a thorough 3-dimensional perception of the landscape morphology as derived by the input elevation dataset. This method is here applied to two test cases showing the performances of the procedure. A website is also addressed where seamless perspective and stereo views of the landscape of the Italian territory preserving the input 10 m or 5 m resolution can be examined

A website to explore the TINITALY/01 DEM

In 2007, a new digital elevation model (DEM) of the whole Italian territory, named TINITALY/01, was presented by Tarquini et al. [2007]. This DEM was the final result of the DIGITALIA project supported by the Italian Ministero dell’Ambiente e della Tutela del Territorio in the framework of a general agreement involving the Istituto Nazionale di Geofisica e Vulcanologia (INGV). The whole database of this DEM, in the form of a 10 m cell size grid, is available to the INGV research community at the web portal Kharita (http://kharita.rm.ingv.it/dmap/). Tarquini et al. [2007] mentioned in short a dedicated website (http://webgis.pi.ingv.it/), where authorized users were allowed to explore full resolution nadiral or perspective shaded relief images (in stereo or conventional format) obtained from the TINITALY/01 DEM. The navigation of this website is now opened to the public. The present technical report illustrates this website, describing its content and unfolding related technological aspects

Multiview 3D reconstruction in geosciences

Multiview three-dimensional (3D) reconstruction is a technology that allows the creation of 3D models of a given scenario from a series of overlapping pictures taken using consumer-grade digital cameras. This type of 3D reconstruction is facilitated by freely available software, which does not require expert-level skills. This technology provides a 3D working environment, which integrates sample/field data visualization and measurement tools. In this study, we test the potential of this method for 3D reconstruction of decimeter-scale objects of geological interest. We generated 3D models of three different outcrops exposed in a marble quarry and two solids: a volcanic bomb and a stalagmite. Comparison of the models obtained in this study using the presented method with those obtained using a precise laser scanner shows that multiview 3D reconstruction yields models that present a root mean square error/average linear dimensions between 0.11 and 0.68%. Thus this technology turns out to be an extremely promising tool, which can be fruitfully applied in geosciences

Release of a 10-m-resolution DEM for the Italian territory: Comparison with global-coverage DEMs and anaglyph-mode exploration via the web

The 10-m-resolution TINITALY/01 DEM (Tarquini et al., 2007) is compared with the two, coarser-resolution, global-coverage, spaceborne-based SRTM and ASTER DEMs and with a high-resolution, LIDAR-derived DEM. Afterwards, we presented a webGIS which allows to explore a 10-m-resolution anaglyph layer showing the landforms of the whole Italian territory in 3D. The webGIS (http://tinitaly.pi.ingv.it/) is open to the public, and can be used to carry out a preliminary analysis of landforms. The TINITALY/01 DEM is available for scientific purposes on the basis of a research agreement (see the above website or write to [email protected])

First evaluation of neutron induced single event effects on the CMS barrel muon electronics

Neutron irradiation tests of the currently available electronics for the CMS barrel muon detector were performed using Thermal and fast neutrons at E< 11MeV. The Single Event Upset rate on the Static RAM was measured, while upper limits are derived for events having experienced no failure. The results are used to guess the upper limits on the mean time between failures in the whole barrel muon detector

The combined use of VIGl@ct (R) (bioMerieux) and fluorescent amplified length fragment polymorphisms in the investigation of potential outbreaks

Even with good surveillance programmes, hospital-acquired infections (HAls) are not always recognized and this may lead to an outbreak. In order to reduce this risk, we propose a model for prompt detection of HAls, based on the use of a real-time epidemiological information system called VIGI@ct (R) (bioMerieux, Las Balmas, France) and on the rapid confirmation or exclusion of the genetic relationship among pathogens using fluorescent amplified length fragment polymorphism (f-AFLP) microbial fingerprinting. We present the results of one year's experience with the system, which identified a total, of 306 suspicious HAls. Of these, 281 (92%) were 'confirmed' by clinical evidence, 16 (5%) were considered to be simple colonization and the tatter nine (3%) were archived as 'not answered' because of the absence of the physician's cooperation. There were seven suspected outbreaks; of these, f-AFLP analysis confirmed the clonal relationship among the isolates in four cases: outbreak 1 (four isolates of Pseudomonas aeruginosa), outbreak 2 (three Escherichia coli isolates), outbreak 6 (two Candida parapsilosis isolates) and outbreak 7 (30 ESPL-producing Klebsiella pneumoniae subsp. pneumoniae). Based on our results, we conclude that the combination of VIGI@ct (R) and f-AFLP is useful in the rapid assessment of an outbreak due to Gram-positive or Gramnegative bacteria and yeasts. (C) 2007 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved

TINITALY/01: a new Triangular Irregular Network of Italy

A new Digital Elevation Model (DEM) of the natural landforms of Italy is presented. A methodology is discussed to build a DEM over wide areas where elevation data from non-homogeneous (in density and accuracy) input sources are available. The input elevation data include contour lines and spot heights derived from the Italian Regional topographic maps, satellite-based global positioning system points, ground based and radar altimetry data. Owing to the great heterogeneity of the input data density, the DEM format that better preserves the original accuracy is a Triangular Irregular Network (TIN). A Delaunay-based TIN structure is improved by using the DEST algorithm that enhances input data by evaluating inferred break-lines. Accordingly to this approach, biased distributions in slopes and elevations are absent. To prevent discontinuities at the boundary between regions characterized by data with different resolution a cubic Hermite blending weight S-shaped function is adopted. The TIN of Italy consists of 1.39×109 triangles. The average triangle area ranges from 12 to about 13000 m2 accordingly to different morphologies and different sources. About 50% of the model has a local average triangle area <500 m2. The vertical accuracy of the obtained DEM is evaluated by more than 200000 sparse control points. The overall Root Mean Square Error (RMSE) is less than 3.5 m. The obtained national-scale DEM constitutes an useful support to carry out accurate geomorphological and geological investigations over large areas. The problem of choosing the best step size in deriving a grid from a TIN is then discussed and a method to quantify the loss of vertical information is presented as a function of the grid step. Some examples of DEM application are outlined. Under request, an high resolution stereo image database of the whole Italian territory (derived from the presented DEM) is available to browse via internet

Treatment comparison in rheumatoid arthritis : head-to-head trials and innovative study designs

Over the last decades, the increasing knowledge in the area of rheumatoid arthritis has progressively expanded the arsenal of available drugs, especially with the introduction of novel targeted therapies such as biological disease modifying antirheumatic drugs (DMARDs). In this situation, rheumatologists are offered a wide range of treatment options, but on the other side the need for comparisons between available drugs becomes more and more crucial in order to better define the strategies for the choice and the optimal sequencing. Indirect comparisons ormeta-analyses of data coming fromdifferent randomised controlled trials (RCTs) are not immune to conceptual and technical challenges and often provide inconsistent results. In this review we examine some of the possible evolutions of traditional RCTs, such as the inclusion of active comparators, aimed at individualising treatments in real-life conditions. Although head-to-head RCTs may be considered the best tool to directly compare the efficacy and safety of two different DMARDs, surprisingly only 20 studies with such design have been published in the last 25 years. Given the recent advent of the first RCTs truly comparing biological DMARDs, we also review the state of the art of head-to-head trials in RA