Analisis Tingkat Literasi Keuangan terhadap Perilaku Konsumtif pada Remaja Sumbawa

Literasi keuangan sangat erat hubungannya dengan manajemen keuangan. Literasi keuangan merupakan salah satu hal pentingbagi setiap individu, salah satunya bagi remaja. Literasi keuangan bagi remaja bertujuan agar remaja dapat terhindar dari suatumasalah keuangan terutama berkaitan dengan perilaku konsumtif, indikator dari manajemen keuangan yaitu (1) pengetahuanumum pengelolaan keuangan, (2) tabungan dan pinjaman, (3) asuransi, (4) investasi. Indikator dari perilaku konsumtif yaitu (1)iklan, (2) lingkungan, (3) pengaruh teman.Penelitian ini bertujuan untuk menguji tingkat literasi keuangan terhadap perilaku konsumtif remaja Sumbawa. Penelitian inimerupakan penelitian Kuantitatif. Metode pengumpulan data dilakukan dengan membagikan kuesioner pada 100 responden yaituremaja Sumbawa. Teknik pengambilan sampel menggunakan purposive sampling. Analisis data yang digunakan yaitu analisisregresi Logistik. Berdasarkan hasil penelitian dapat disimpulkan bahwa terdapat pengaruh negatif signifikan antaraliterasikeuangan terhadap perilaku konsumtif. Dimana semakin tinggi literasi keuangan maka perilaku konsumtif akan menurun

The Effects of Aqueous Extract of Wild Pistachio (Pistacia Atlantica) leaves on Diabetic Nephropathy in Rat

Background & aim: Due to increased public interest in the use of herbal medicine, their efficacy and safety evaluation have become important. In some studies, Pistacia atlantica leave (PAL) extract suggested as a hypoglycemic agent. However, there is no study about its effects on diabetic nephropathy. Therefore, the present work was conducted to evaluate the effects of aqueous extract of PAL on some biochemical and pathological aspects related to renal function in diabetic rats. Methods: In the present experimental study, 40 severe diabetes male Wistar rats (180-200 gr) with STZ and eight healthy rats at the same age were equally divided into 6 groups and followed for a period of thirty days as the oral treatment respectively. Diabetic groups I ,II and III received 100, 200 and 400 mg/kg of PAL extracts, diabetic group IV received 50 mg/kg Captopril and diabetic group&nbsp; V and healthy group received saline 0.9% as control groups. Finally, fasting blood glucose (FBG), Urine volume and 24 h urine total protein (UTP), blood nitrogen urea (BUN) and plasma creatinine (Cr) were assessed biochemically and also qualitative renal histomorphological alterations were assessed pathologically. Data were analyzed using one-way ANOVA and Tukey post hoc test. Results: In diabetic control group the FBS (383.5 &plusmn; 118.33), BUN (27.17&plusmn; 2.86), Cr (1.3 &plusmn; 0.45), Urine volume (24.66&plusmn; 5.10) and UTP (25.67 &plusmn; 1.51) of groups 1-5 significantly increased in comparison whit normal control group (p<0.0001 each). In addition:&nbsp; severe glomerolosclerosis, mesangial matrix expansion and tuft-capsule adhesion were observed in diabetic rats. Unlike captopril, which could significantly reduce the mean level of urea nitrogen (p <0.001; 12.5 &plusmn; 2.81), creatinine (p=0.034; 0.97&plusmn;0.14) and protein (p=0.002: 13.66 &plusmn; 3.48) compared with diabetic controls the histology of the group was evaluate and confirmed its moderator effects, Conclusion: The results clearly demonstrate that PAL did not have any beneficial effects on diabetic nephropathy in rats

Implantation of human olfactory ecto-mesenchymal stem cells restores locomotion in a rat model of Parkinson's disease

One of the complex neurodegenerative disorders is Parkinson disease (PD). PD is mainly caused by dopaminergic (DAergic) neuron degeneration in the midbrain. The loss of DAergic neurons is considered as a key reason of motor functional defects in PD patients. Cell replacement strategies are considered as an alternative remedy to effectively address neurodegeneration in PD. In this report, we evaluated the restorative effect of human olfactory ecto-mesenchymal stem cells (OE-MSCs) in rat models of PD. Accordingly, human OE-MSCs were isolated and phenotypically characterized by flow cytometry and immunocytochemistry. Next, the undifferentiated OE-MSCs were unilaterally transplanted into the striatum of 6-hydroxydopamine (6-OHDA)-lesioned rat models, followed by molecular and histological analyzes as well as assessment of motor skills. Our results displayed that the grafting of OE-MSCs increased the expression of DAergic markers namely dopamine transporter (DAT), tyrosine hydroxylase (TH), nuclear receptor related-1 (Nurr1) in a 6-OHDA model compared with that of control, detected by immunohistochemical staining and western blot. Moreover, noticeable improvements in motor coordination, muscle activity and locomotor performance were observed in 6-OHDA model of PD following OE-MSCs transplantation. Taken together, our finding indicates that undifferentiated OE-MSCs might be counted as an appropriate source for cell replacement therapy particularly aimed at PD. © 2021 Elsevier B.V

Chronic administration of methylphenidate did not affect memory and GDNF levels but increase astrogliosis in adult male rat's hippocampus

Background: ADHD is the most common developmental disorder affecting approximately three to seven percent of school-aged children and 2.5 percent of adults worldwide. The drug of choice for the pharmacotherapy of ADHD is Methylphenidate (MPH). However, there is growing concerns about side effects resulting from its potential interference with brain anatomical and behavioral development. Aim: This article focuses on the adverse effects of MPH on the rat's hippocampus. Methods: The animals received an oral dose of 5 mg/kg MPH or normal saline, as the vehicle, on a daily basis for 30 days. Y-maze test, passive avoidance, Barnes maze and field potential recording were conducted. Western blot for detecting the neurotrophic factor of GDNF and immunohistochemistry of astrogliosis were performed. Results: Our results revealed that MPH treatment suppressed the willingness of rats to explore new environments. Also, it had no effect on improving long-term potentiation, long-term memory and spatial memory in the MPH group as opposed to the control group. There was also a significant increase of astrogliosis in the treated rats� hippocampi. On the other hand, there was not a significant relationship between MPH administration and the decrement of the GDNF level. Conclusion: We encourage the need to conduct more research on the adverse effects of MPH on the brain. © 2020 Elsevier B.V

Recent advances in chromosome capture techniques unraveling 3D genome architecture in germ cells, health, and disease

Abstract In eukaryotes, the genome does not emerge in a specific shape but rather as a hierarchial bundle within the nucleus. This multifaceted genome organization consists of multiresolution cellular structures, such as chromosome territories, compartments, and topologically associating domains, which are frequently defined by architecture, design proteins including CTCF and cohesin, and chromatin loops. This review briefly discusses the advances in understanding the basic rules of control, chromatin folding, and functional areas in early embryogenesis. With the use of chromosome capture techniques, the latest advancements in technologies for visualizing chromatin interactions come close to revealing 3D genome formation frameworks with incredible detail throughout all genomic levels, including at single-cell resolution. The possibility of detecting variations in chromatin architecture might open up new opportunities for disease diagnosis and prevention, infertility treatments, therapeutic approaches, desired exploration, and many other application scenarios

Rice Data Systems for Sub-Saharan Africa: Contribution to the Japan-AfricaRice Emergency Rice Project

The rice data system for sub-Saharan Africa, which is a contribution to the Japan-AfricaRice Emergency Rice Initiative, is funded by the government of Japan. The project was coordinated at the regional level by Africa Rice Center (AfricaRice) and implemented at national levels by the national focal points. Throughout the course of the project implementation, the country focal points have made substantial and active contributions to ensure a smooth coordination of the project in-country activities. The national focal points are from the national agricultural research systems (NARS) and the national agricultural statistical services (NASS) of the countries that are members of the Coalition for African Rice Development (CARD). To ensure an effective communication between the project coordination unit and the countries, an intensive networking was established, which included sending of quarterly progress reports by the countries. Overall, the implementation of the project activities went well and it demonstrated the feasibility of building long-term collaborative working relationships between several national stakeholders to sustainably develop a multipurpose rice data systems. The surveys helped the countries develop well-structured rice statistical databases. Overall, the project activities went well and the national surveys were successfully conducted in the majority of the countries leading to the development of up-to-date and accessible rice data and information. In fact, as future project activities, the country teams will work to conduct in-depth analysis of the data collected in this project to update the national rice development strategies (NRDS), conduct rice research priority setting exercises and publish papers and policy briefs. AfricaRice discussed with the main donor in Japan who accepted that in-depth analysis of the data collected can continue after 30 April 2010, to publish the data in Google Map and transform the country reports into final and more comprehensive reports