3,535 research outputs found

    Sensitivity to the KARMEN Timing Anomaly at MiniBooNE

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    We present sensitivities for the MiniBooNE experiment to a rare exotic pion decay producing a massive particle, Q^0. This type of decay represents one possible explanation for the timing anomaly reported by the KARMEN collaboration. MiniBooNE will be able to explore an area of the KARMEN signal that has not yet been investigated

    Paradoxic septal motion during PEEP ventilation

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    Validity of the "Drift without pronation" sign in conversion disorder.

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    BACKGROUND: Conversion disorder (CD) is a psychiatric disorder, yet the diagnosis cannot be established without the expertise of a neurologist, as distinguishing a functional from an organic symptom relies on careful bedside examination. Joseph Babinski considered the absence of pronator drift as a 'positive sign' for hysterical paresis but the validity of this sign has never been evaluated. The aim of this study was to examine the sensitivity and specificity of the "drift without pronation" sign. METHODS: Twenty-six patients with unilateral functional upper limb paresis diagnosed with CD (DSM-IV) and a control group of 28 patients with an organic neurological condition were consecutively included. The arm stabilisation test was performed with arms stretched out in full supination, fingers adducted, eyes closed for 10 seconds. A positive "drift without pronation" sign was defined by the presence of a downward drift without pronation. RESULTS: All CD subjects (100%) displayed a positive sign when only 7.1% of organic subjects did (Fisher's p < 0.001). The sign yielded a sensitivity of 100% (95% CI:84%-100%) and a specificity of 93% (95% CI:76%-98%). CONCLUSION: The observation of a "drift without pronation" sign is specific for Conversion Disorder and can be of help in making a quick distinction between organic and functional paresis at the bedside

    The value of 'positive' clinical signs for weakness, sensory and gait disorders in conversion disorder: a systematic and narrative review.

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    Experts in the field of conversion disorder have suggested for the upcoming DSM-V edition to put less weight on the associated psychological factors and to emphasise the role of clinical findings. Indeed, a critical step in reaching a diagnosis of conversion disorder is careful bedside neurological examination, aimed at excluding organic signs and identifying 'positive' signs suggestive of a functional disorder. These positive signs are well known to all trained neurologists but their validity is still not established. The aim of this study is to provide current evidence regarding their sensitivity and specificity. We conducted a systematic search on motor, sensory and gait functional signs in Embase, Medline, PsycINfo from 1965 to June 2012. Studies in English, German or French reporting objective data on more than 10 participants in a controlled design were included in a systematic review. Other relevant signs are discussed in a narrative review. Eleven controlled studies (out of 147 eligible articles) describing 14 signs (7 motor, 5 sensory, 2 gait) reported low sensitivity of 8-100% but high specificity of 92-100%. Studies were evidence class III, only two had a blinded design and none reported on inter-rater reliability of the signs. Clinical signs for functional neurological symptoms are numerous but only 14 have been validated; overall they have low sensitivity but high specificity and their use should thus be recommended, especially with the introduction of the new DSM-V criteria

    Tight Bounds for MIS in Multichannel Radio Networks

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    Daum et al. [PODC'13] presented an algorithm that computes a maximal independent set (MIS) within O(log2n/F+lognpolyloglogn)O(\log^2 n/F+\log n \mathrm{polyloglog} n) rounds in an nn-node multichannel radio network with FF communication channels. The paper uses a multichannel variant of the standard graph-based radio network model without collision detection and it assumes that the network graph is a polynomially bounded independence graph (BIG), a natural combinatorial generalization of well-known geographic families. The upper bound of that paper is known to be optimal up to a polyloglog factor. In this paper, we adapt algorithm and analysis to improve the result in two ways. Mainly, we get rid of the polyloglog factor in the runtime and we thus obtain an asymptotically optimal multichannel radio network MIS algorithm. In addition, our new analysis allows to generalize the class of graphs from those with polynomially bounded local independence to graphs where the local independence is bounded by an arbitrary function of the neighborhood radius.Comment: 37 pages, to be published in DISC 201

    Orion Capsule Parachute Assembly System (CPAS) Overload Testing Approach and Results

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    The qualification of the Orion Capsule Parachute Assembly System (CPAS) system includes exposure to loads and dynamic pressures above the required values as validation of the parachutes' structural integrity. As outlined in the certification plan, each of the four parachutes of the system are to be subjected to 110% of their respective maximum dynamic pressure requirements. The Main and Drogue parachutes have satisfied this overload condition in drop testing and due to cost and schedule constraints, the Forward Bay Cover Parachute (FBCP) and Pilot parachute were subjected to the overload condition in the ground testing described in this document. The test objectives and pass/fail criteria were established and require the parachutes to achieve and maintain a target riser load (associated with a minimum of 110% dynamic pressure overload) for a minimum of three seconds while sustaining no failures of any structural members (vent hoop, radials, suspension line) or any damage which propagates into catastrophic failure of the canopy. Considering the assumptions and limitations associated with the ground testing (primarily non-uniform flow field of the ground test system and variations in parachute manufacturing), a method of establishing the desired overload condition was determined by the technical community and covers the 2-sigma bounds of the drag area distribution derived from drop testing. On June 27, 2017 the testing was executed at the High Velocity Airflow System (HiVAS) facility located at the Weapon Survivability Laboratory (WSL) at the Naval Air Warfare Center, Weapons Division (NAWCWD) China Lake. Engineering Development Unit (EDU) parachutes were used as pathfinders to gain experience with achieving the test conditions. Additional runs were executed to measure the airflow at the same location as the canopy skirt, although this data is not required to satisfy the test objectives and parachute pass/fail criteria. The qualification parachutes were successfully exposed to the target conditions and sustained only minor damage

    The Heavy-Flavour Contribution to Proton Structure

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    We present theoretical and experimental considerations pertaining to deeply inelastic heavy-flavour production at HERA. The various theoretical uncertainties in the cross section calculation are discussed. Cuts are imposed to determine the fraction of charm production accessible to the detectors. The production of charm at asymptotic Q2Q^2 and bottom production are also covered. Experimental aspects include current charm production data analysis and prospects for future analyses including anticipated high precision and distinguishing photon-gluon fusion charm events from excitation from the charm parton density. The feasibility of measuring F2bb(x,Q2)F_2^{b\overline b}(x,Q^2) is investigated.Comment: 22 total pages with 16 figures. To appear in abbreviated form in the proceedings of the workshop ``Future Physics at HERA'', DESY, Hamburg, 199

    Autobiographical Memory for Emotional Events in Amnesia

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    This study investigated autobiographical memory for emotionally flavoured experiences in amnesia. Ten amnesic patients and 10 matched control subjects completed the Autobiographical Memory Interview and three semi-structured interviews which assessed memory for personal events associated with pain, happiness and fear. Despite retrograde amnesia for autobiographical facts and incidents, amnesics remembered a similar number of emotionally significant personal experiences as control subjects. Their recollections generally lacked elaboration and detail, but pain-related memories appeared to be more mildly impaired than memories associated with happiness and fear. The findings are discussed in relation to recent views on the relationship between affect and memory

    Development of an experimental 10 T Nb3Sn dipole magnet for the CERN LHC

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    An experimental 1-m long twill aperture dipole magnet developed using a high-current Nb3Sn conductor in order to attain a magnetic field well beyond 10 T at 4.2 K is described. The emphasis in this Nb3Sn project is on the highest possible field within the known Large Hadron Collider (LHC) twin-aperture configuration. A design target of 11.5 T was chosen
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