A New Journal in the Field of Pharmaceutical Technology Is Born

Launching a new journal is always an adventure. There are so many tasks, so many people to convince from the publisher to the authors. After many discussions at the GERPAC’s meetings every year in the south of France, we decided that the game was worth the candle. In fact, few journals are dedicated to the field of Pharmaceutical Technology in Hospitals. Very often the scopes of the scientific journals are wider and it is difficult for authors to communicate over much focused technical questions in those papers. This is why Pharmaceutical Technology in Hospital Pharmacy (PTHP) was launched. We are committed to produce a high-quality scientific international journal because our profession really needs it. This journal will be dedicated to all angles of pharmaceutical technologies in hospitals from sterile compounding to electronic devices related to drug production or distribution. Sterilization and radiopharmacy are also considered in this new journal. Detailed aims and scope are provided in this issue along with the instructions to authors. The editorial board of the journal gather hospital pharmacists and scientific researchers all having a strong background in applied research and scientific publishing, holding also a PhD and being for most of them professors of pharmaceutical technology in Universities from European and extra European Universities. [...

Evaluation of radiopharmaceuticals sorption to 2 and 3-pieces syringes.

International audienc

A proof of principle study using radiopharmaceuticals to quantify and localize container-content interactions in medical syringes

The sorption of drugs onto their contents is a known phenomenon that is difficult to analyse precisely. The purpose of this study was to present a non-invasive method for locating and quantifying sorption phenomena using radiopharmaceuticals. Radiopharmaceutical are medicines armed with a radionuclide enabling quantification and imaging using dedicated scanners. The sorption of nine different radiopharmaceuticals on 2- and 3-part syringes was investigated. These syringes were filled with the studied radiopharmaceutical solutions and stored immobile for 3 h. At different times ranging from 0 to 180 min, 10 µL were taken from the syringes and the radioactivity of these samples was determined by a gamma counter. 5 radiopharmaceuticals exhibited no significant sorption at any time point in both 2 and 3-parts syringes, but 4 radiopharmaceuticals exhibited sorption losses varying from 20 to 33% after 3 h contact with 3-part-syringes, but no sorption on 2-part syringes at any time point. [Tc]Tc-tetrofosmine Single Photon Emission Computed Tomography/Computed Tomography imaging indicated clearly that the interactions were located on the rubber plunger of the 3-part-syringes. The specific nature of radiopharmaceuticals allowed their use as an innovative method to quantify and localize drug sorption phenomena