Atmospheric environment for Space Shuttle (STS-3) launch

Selected atmospheric conditions observed near Space Shuttle STS-3 launch time on March 22, 1982, at Kennedy Space Center, Florida are summarized. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud), and winds aloft are included. The sequence of prlaunch Jimsphere measured vertical wind profiles and the wind and thermodynamic parameters measured at the surface and aloft in the SRB descent/impact ocean area are presented. Final meteorological tapes, which consist of wind and thermodynamic parameters versus altitude, for STS-3 vehicle ascent and SRB descent were constructed. The STS-3 ascent meteorological data tape is constructed

Wind models for the NSTS ascent trajectory biasing for wind load alleviation

New concepts are presented for aerospace vehicle ascent wind profile biasing. The purpose for wind biasing the ascent trajectory is to provide ascent wind loads relief and thus decrease the probability for launch delays due to wind loads exceeding critical limits. Wind biasing trajectories to the profile of monthly mean winds have been widely used for this purpose. The wind profile models presented give additional alternatives for wind biased trajectories. They are derived from the properties of the bivariate normal probability function using the available wind statistical parameters for the launch site. The analytical expressions are presented to permit generalizations. Specific examples are given to illustrate the procedures. The wind profile models can be used to establish the ascent trajectory steering commands to guide the vehicle through the first stage. For the National Space Transportation System (NSTS) program these steering commands are called I-loads

Absence of force suppression in rabbit bladder correlates with low expression of heat shock protein 20

BACKGROUND: Nitroglycerin can induce relaxation of swine carotid artery without sustained reductions in [Ca(2+)](i )or myosin regulatory light chain (MRLC) phosphorylation. This has been termed force suppression and been found to correlate with ser(16)-phosphorylation of heat shock protein 20 (HSP20). We tested for the existence of this mechanism in a smooth muscle that is not responsive to nitric oxide. METHODS: Isometrically mounted mucosa free rabbit bladder strips were contracted with carbachol and relaxed with 8-Br-cGMP, forskolin, or isoprenaline. RESULTS: Contraction was associated with a highly cooperative relation between MRLC phosphorylation and force such that very small increases in MRLC phosphorylation induced large increases in force. Relaxation induced by 8-Br-cGMP, forskolin, or isoprenaline did not shift the MRLC phosphorylation-force relation from that observed with carbachol alone, i.e. there was no force suppression. HSP20 content was negligible (approximately two hundred-fold less than swine carotid). CONCLUSION: The lack of force suppression in the absence of HSP20 is consistent with the hypothesized role for HSP20 in the force suppression observed in tonic smooth muscles

Atmospheric observations for STS-3 landing

Synoptic weather conditions existing over the western United States for the time of Shuttle descent are presented. The techniques and methods used to furnish synoptic atmospheric data at the surface and aloft for flight verification of the STS 3 orbiter during its descent are specified. Examples of the upper level data set are given

Importance of the Natural Terrestrial Environment with Regard to Advanced Launch Vehicle Design and Development

The terrestrial environment is an important forcing function in the design and development of the launch vehicle. The scope of the terrestrial environment includes the following phenomena: Winds; Atmospheric Thermodynamic Models and Properties; Thermal Radiation; U.S. and World Surface Environment Extremes; Humidity; Precipitation, Fog, and Icing; Cloud Characteristics and Cloud Cover Models; Atmospheric Electricity; Atmospheric Constituents; Vehicle Engine Exhaust and Toxic Chemical Release; Occurrences of Tornadoes and Hurricanes; Geological Hazards, and Sea States. One must remember that the flight profile of any launch vehicle is in the terrestrial environment. Terrestrial environment definitions are usually limited to information below 90 km. Thus, a launch vehicle's operations will always be influenced to some degree by the terrestrial environment with which it interacts. As a result, the definition of the terrestrial environment and its interpretation is one of the key launch vehicle design and development inputs. This definition is a significant role, for example, in the areas of structures, control systems, trajectory shaping (performance), aerodynamic heating and take off/landing capabilities. The launch vehicle's capabilities which result from the design, in turn, determines the constraints and flight opportunities for tests and operations

Hepatitis E Virus Variant in Farmed Mink, Denmark

Hepatitis E virus (HEV) is a zoonotic virus for which pigs are the primary animal reservoir. To investigate whether HEV occurs in mink in Denmark, we screened feces and tissues from domestic and wild mink. Our finding of a novel HEV variant supports previous findings of HEV variants in a variety of species

Expressions 1984

https://openspace.dmacc.edu/expressions/1008/thumbnail.jp