Full phase diagram of isolated skyrmions in a ferromagnet

Magnetic skyrmions are topological quasi particles of great interest for data storage applications because of their small size, high stability, and ease of manipulation via electric current. Theoretically, however, skyrmions are poorly understood since existing theories are not applicable to small skyrmion sizes and finite material thicknesses. Here, we present a complete theoretical framework to determine the energy of any skyrmion in any material, assuming only a circular symmetric 360$^\circ$ domain wall profile and a homogeneous magnetization profile in the out-of-plane direction. Our model precisely agrees with existing experimental data and micromagnetic simulations. Surprisingly, we can prove that there is no topological protection of skyrmions. We discover and confirm new phases, such as bi-stability, a phenomenon unknown in magnetism so far. The outstanding computational performance and precision of our model allow us to obtain the complete phase diagram of static skyrmions and to tackle the inverse problem of finding materials corresponding to given skyrmion properties, a milestone of skyrmion engineering

Stabilisierung sub- und pertrochantärer Femurfrakturen mit dem PFNΑ®

Zusammenfassung: Operationsziel: Primär belastungsstabile Osteosynthese per- und subtrochantärer Femurfrakturen mit intramedullärem Kraftträger, besonders auch in osteoporotischem Knochen. Rasche Wiederherstellung der Anatomie und Funktion des verletzten Beins. Indikationen: Sämtliche per- und subtrochantäre Frakturen der AO-Klassifikation 31-A. Kontraindikationen: Offene Wachstumsfugen und ungeeignete Femuranatomie (pathologische Antekurvation bzw. fehlverheilte Schaftfrakturen). Operationstechnik: Wenn möglich geschlossene, bei Bedarf offene Reposition der Faktur auf dem Extensionstisch. Intramedulläre, unaufgebohrte Nagelung und Frakturfixation durch Einbringen einer Spiralklinge über einen Führungsdraht in das Kopf-Halsfragment. Möglichkeit zur dynamischen oder statischen Verriegelung im Femurschaft. Operative Nachsorge: Rasche Mobilisation ab dem ersten postoperativen Tag mit schmerzadaptierter Vollbelastung. Thromboseprophylaxe für 6Wochen mit Fondaparinux, Rivaroxaban oder niedermolekularem Heparin (NMH), alternativ orale Antikoagulation. Ergebnisse: Im Rahmen einer AO-Multizenterstudie an 11 europäischen Kliniken wurden zwischen April 2004 und Juni 2005 313Patienten (Durchschnittsalter 80,6Jahre, 77% Frauen, 23% Männer) mit 315 instabilen pertrochantären Frakturen mittels PFNΑ® ("proximal femoral nail antirotation") operativ stabilisiert [24]. Bei 82% handelte es sich um 31-A2-Frakturen, bei 18% um 31-A3-Frakturen. Die durchschnittliche Operationszeit betrug 56min für die A2-Frakturen und 66min für die A3-Frakturen. Die durchschnittliche Liegedauer im Akutspital betrug 12Tage. Bei 72% der Patienten konnte ein Repositions- und Stabilisierungsergebnis erreicht werden, welches eine unmittelbare postoperative Vollbelastung erlaubte. Insgesamt wurden 165Komplikationen beobachtet, 117 davon waren nicht auf das Implantat zu beziehen. 46 operationsbedingte Komplikationen führten zu 28 ungeplanten Re-Operationen (u.a. 7Femurschaftfrakturen, 4 azetabuläre Penetrationen). 56% der Patienten konnten über ein ganzes Jahr nachkontrolliert werden. Nach einem Jahr waren 89% der Frakturen konsolidiert. Die höchsten Komplikationsraten wiesen Frakturen der Morphologie 31-A2.3 sowie Patienten älter als 90Jahre auf. Mit dem PFNA® wurde damit eine mit den Resultaten anderer intra- und extramedullärer Implantate vergleichbare Anzahl operationsbedingter Komplikationen (14,6%) beschriebe

Super-resolving multi-photon interferences with independent light sources

We propose to use multi-photon interferences from statistically independent light sources in combination with linear optical detection techniques to enhance the resolution in imaging. Experimental results with up to five independent thermal light sources confirm this approach to improve the spatial resolution. Since no involved quantum state preparation or detection is required the experiment can be considered an extension of the Hanbury Brown and Twiss experiment for spatial intensity correlations of order N>2

Depressed and excluded: Do depressive symptoms moderate recovery from ostracism?

Background. Prior studies show that depressed individuals react with more immediate reflexive need threat to ostracism than healthy controls. However, it remains unclear whether the observed difference between depressed individuals and healthy controls is caused by ostracism. To find out, the exclusion condition needs to be compared to a baseline condition: inclusion. Methods. We assessed depressive symptoms in N = 426 participants in an experimental study. Participants were included or excluded in Cyberball and indicated both their immediate reflexive need satisfaction level and their reflective need satisfaction level several minutes later to assess recovery. Results. Being excluded decreased reflexive need satisfaction levels for all participants. At the same time, the strength of depressive symptoms negatively predicted reflexive and reflective need satisfaction and was associated with slower recovery. Importantly, no moderation was observed: individuals with more depressive symptoms reported reduced need satisfaction levels regardless of being included or excluded in Cyberball. Limitations. The present findings were obtained with one paradigm only, albeit the most commonly used one: Cyberball. Depressive symptoms were assessed as self-report; future studies may wish to replicate the effects using structured clinical interviews. Conclusions. Depressive symptoms come with lowered need satisfaction levels, irrespective of whether individuals are socially excluded or included. Clinical practitioners should be aware of the relationship between chronic need threat and depression in order to help their patients overcome it

Stable Magnetostatic Solitons in Yttrium Iron Garnet Film Waveguides for Tilted in-Plane Magnetic Fields

The possibility of nonlinear pulses generation in Yttrium Iron Garnet thin films for arbitrary direction between waveguide and applied static in-plane magnetic field is considered. Up to now only the cases of in-plane magnetic fields either perpendicular or parallel to waveguide direction have been studied both experimentally and theoretically. In the present paper it is shown that also for other angles (besides 0 or 90 degrees) between a waveguide and static in-plane magnetic field the stable bright or dark (depending on magnitude of magnetic field) solitons could be created.Comment: Phys. Rev. B (accepted, April 1, 2002

Investigation of the Dzyaloshinskii-Moriya interaction and room temperature skyrmions in W/CoFeB/MgO thin films and microwires

Recent studies have shown that material structures, which lack structural inversion symmetry and have high spin-orbit coupling can exhibit chiral magnetic textures and skyrmions which could be a key component for next generation storage devices. The Dzyaloshinskii-Moriya Interaction (DMI) that stabilizes skyrmions is an anti-symmetric exchange interaction favoring non-collinear orientation of neighboring spins. It has been shown that material systems with high DMI can lead to very efficient domain wall and skyrmion motion by spin-orbit torques. To engineer such devices, it is important to quantify the DMI for a given material system. Here we extract the DMI at the Heavy Metal (HM) /Ferromagnet (FM) interface using two complementary measurement schemes namely asymmetric domain wall motion and the magnetic stripe annihilation. By using the two different measurement schemes, we find for W(5 nm)/Co20Fe60B20(0.6 nm)/MgO(2 nm) the DMI to be 0.68 +/- 0.05 mJ/m2 and 0.73 +/- 0.5 mJ/m2, respectively. Furthermore, we show that this DMI stabilizes skyrmions at room temperature and that there is a strong dependence of the DMI on the relative composition of the CoFeB alloy. Finally we optimize the layers and the interfaces using different growth conditions and demonstrate that a higher deposition rate leads to a more uniform film with reduced pinning and skyrmions that can be manipulated by Spin-Orbit Torques

Personalized Hepatobiliary Cancer Treatment

Personalized treatments for biliary tract carcinoma patients could improve the overall outcomes, mainly by withholding treatments from patients who are unlikely to benefit from surgery or chemotherapy. In order to determine the best treatment, at the optimal time in the disease course, in the center with the best outcomes, for each individual patient, large databases have to be utilized to construct appropriate validated models. The works included in this thesis aim to contribute to the development of personalized medicine using accurate prognostication and prediction rules

Field-free deterministic ultra fast creation of skyrmions by spin orbit torques

Magnetic skyrmions are currently the most promising option to realize current-driven magnetic shift registers. A variety of concepts to create skyrmions were proposed and demonstrated. However, none of the reported experiments show controlled creation of single skyrmions using integrated designs. Here, we demonstrate that skyrmions can be generated deterministically on subnanosecond timescales in magnetic racetracks at artificial or natural defects using spin orbit torque (SOT) pulses. The mechanism is largely similar to SOT-induced switching of uniformly magnetized elements, but due to the effect of the Dzyaloshinskii-Moriya interaction (DMI), external fields are not required. Our observations provide a simple and reliable means for skyrmion writing that can be readily integrated into racetrack devices